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21 Cards in this Set
- Front
- Back
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Where does Staph pseudintermedius normally hang out
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Hair vs skin
anal region nasal carriage |
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What are the important byproducts of Staph pseudintermedius
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-Beta-lactamase
-Protein A: degranulates mast cells, fixes complement -*Proteases -Slime |
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What is the pathogenesis of bacterial infection
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-increase adherence of Staph to skin cells in atopic animals
-inflammatory mediators change microclimate -permeability changes allow serum leakage and increased humidity -cutaneous temp change |
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What are predisposing physical factors for pyoderma
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Signalment - short coated
anatomic - multiple folds Environmental - humidity, temperature |
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What are predisposing diseases for pyoderma
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-*Atopic dermatitis
-*Endocrine: hypothyroidism -Ectoparasites -Cornification disorder -Immunodeficiency |
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What are Clinical features of pyoderma
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erythema
crust / scale exudate fistulous draining tract patchy alopecia |
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How do papules progress
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papule
pustule epidermal collarette |
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What are clinical features of pyoderma
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pruritis (2-4 itch)
patchy alopecia to diffuse thinning folliculitis signs do vary |
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What are differentials for pustules
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pyoderma
autoimmune disease sterile eosinophilic pustules dermatophytosis sterile pyogranulomatous dermatitis |
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What are appropriate diagnostics
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Cytology!
history PE dermatology data base CBC/Chem |
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What indicates presence of bacteria on a slide
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in pairs / cluster
indicate Staph |
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What are indications for bacterial culture and sensitivity
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Recurring cases
Unexpected cytology (ex: rod bacteria) Failure to respond to SOC therapy (indicate reistant bacteria) |
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What are topical antimicrobial therapy options
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Benzoyl peroxide
Mupirocin |
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What are best shampoo therapy options
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Benzyol peroxide (best - 48 hours efficacy) > Chlorhex > organiz iodine > triclosan-sulfur-salicylic acid > control
Kwochka 1991 study |
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When are shampoo therapy indicated
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superficial infections only
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What shampoo product was shown to be the best against Staph in dogs
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Benzoyl peroxide > Chlorhexidine > Organic iodine > triclosan-sulfur-salicyclic acid > control
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What is the benefit of whirlpool therapy
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Remove surface debris
reduce pain increase blood flow to skin |
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What are the indications of a good antimicrobial drug
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-Effective against causative organism (Staph)
-Bactericidal -reach appropriate concentration in affected tissues / cells -proper dose -treat for sufficient time |
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What ab should you NOT use against Staph pseud
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TAPAS
Tetracycline ampicllin penicllin amoxicillin sulfas |
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How long should most pyoderma be treated (Starting point)
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30 days
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What ab are effective against Staph pseud
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Fluroquinolones
potentiated amoxicillin synthetic penicillin Cephalexin / Cephadroxil / Cefpodoxime |
