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17 Cards in this Set
- Front
- Back
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How do you dose Ivermectin therapy
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0.5 mg/kg dosed orally SID for 90-120 days
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how many mls of 1% Ivermectin should be given for 44 lb dog once you achieve induction for every day treatment (maintenance)
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1% ivermectin = 1g/100 ml = 10mg/ml (concentration)
44 lb dog / 2.2 kg/lb = 20 kg 0.5 mg/kg x 20kg = 10 mg 10 mg x 10 mg/ml = 1 ml / day |
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What are adverse effects of oral ivermectin treatment
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neurotoxicity - ataxia, gi upset, weakness, seizures
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how long do you treat with Ivermectin for
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30 days past 2nd negative scraping
if (+) treat for 2 weeks then recheck |
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What dogs can be affected by MDR1 gene mutation
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collies
shelties whippets australian shepard rottweiller herding breed dogs |
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How can you check for MRD1 gene mutation when using oral Ivermectin dosing
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start with gradual dosing and check for effects
send out blood sample for WSU |
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How do you use Milbemycin oxime (Interceptor, Sentinel) for demodicosis
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0.5-1.0 mg/kg BID for 90-180 days
$$$ not for use in avermectin sensitive Collies |
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What drugs should you not use to treat Demodicosis
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Doramectin (low response, dont use in off label species = death)
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How do you treat Demodicosis in dogs
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Ivermectin
Amitraz Milbemycin |
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How does D.gatoi present in cats
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alopecia
pruritis self induced alopecia - symmetrical hair loss |
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How do you diagnose D.gatoi in cats
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skin scraping - clip hair first (10 x objective)
fecal floatation histopathology history and CS / response to weekly lime sulfur dips (D. gatoi) |
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How do you treat D. gatoi in cats
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Lime sulfur rinses - weekly up to 5 treatments
Moxidectin / Advantage multi - not effective in every case: every 2 weeks Topical amitraz (careful cats sensitive) |
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What are important client ed points with Demodicosis
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castrate - heriditary
usually good prognosis dont use glucocorticoids search for underlying disease in older patients |
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A collie walks into your clinic with a known MDR1 gene mutation..what drugs can you NEVER give it
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LIViD CAD
L: Loperamide I: Ivermectin V: vincristine/vinblastine D: Doxorubricin C: Cyclosporin A: Acepromazine D: Digoxin |
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what is the biggest failure for demodicosis
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stopping treatment too early
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What are adverse effects of Amitraz / Mitaban
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lethargy
bradycardia depression |
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How do you use Moxidectin / Advantage multi for Demodicosis
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applied every week
$$$ off label |
