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203 Cards in this Set
- Front
- Back
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List all the different primary skin lesions
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Macule, Patch, Papule, Plaque, Nodule, Tumor, Vesicle, Bulla, Pustule, Wheal
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A primary nonpalpable, circumscribed lesion of the skin <1cm across might be a
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Macule
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A primary nonpalpable, circumscribed lesion of the skin >1cm across might be a
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Patch
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A primary elevated, circumscribed lesion of the skin <1cm across without fluid might be a
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Papule
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A primary elevated, circumscribed lesion of the skin >1cm across without fluid might be a
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Plaque
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A primary palpable, solid, round lesion, >1cm, arising from dermis might be a
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Nodule
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A primary large mass >2cm, with potentially variable depth, shape, and consistency might be a
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Tumor
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A primary, circumscribed, clear fluid filled elevation, <1cm might be called a
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Vesicle
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A primary, circumscribed, clear fluid filled elevation, >1cm might be called a
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Bulla
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A primary circumscribed, superficial pus-filled lesion might be called a
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Pustule
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A primary transient edematous plateau-like elevation, oval-arcuate, pink-red lesion might be called a
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Wheal
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List the eight secondary skin lesions
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Scale, erosion, ulcer, crust, fissure, excoriation, atrophy, scar
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A secondary skin lesion with a collection of dead stratum corneum might be a
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Scale
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A secondary lesion with loss of epidermis that heals without scarring might be a
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Erosion
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A secondary lesion with a loss of all epidermis and some dermis might be a
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Ulcer
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A secondary lesion with a dried collection of serum and blood cells on the surface
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Crust (scab)
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A secondary lesion that is a linear cleft through the epidermis into the dermis
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Fissure
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A secondary lesion that is an erosion caused by scratching is known as
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Excoriation
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A secondary lesion that has thinning of the skin leading to a depression is known as
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Atrophy
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A special skin lesion that has thickening of the skin from scratching is known as
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Lichenification
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A special skin lesion that has a narrow elevated tortuous lesion from burrowing parasite is known as
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Burrow
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A blanchable skin lesion is blanchable because
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It has dilated vessels
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An example of a blanchable skin lesion is
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Telangiectasias (Rosacea, spider angioma)
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A non-blanchable skin lesion is not blanchable because
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There is hemorrhage/RBCs in the dermis
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A non-blanchable red macule might be called
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petechia
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A non-blanchable red-purple patch from intradermal hemorrhage>1cm is
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Ecchymoses
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A palpable non-blanchable lesion associated with leukocytoclastic vasculitis
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Palpable purpura
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A KOH test is used to diagnose what
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Tinea (hyphae in skin or hair)
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A Tzanck test is used to diagnose what
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HSV and VZV caused skin issues
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In phototherapy, UVA/UVB does what
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Targets lymphocytes in the skin
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Phototherapy treats what skin lesions/issues
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Psoriasis, atopic dermatitis, generalized pruritis, mycosis fungiodes, acne
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Describe transient synovitis in children
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3-7yo
M>F Acute onset of hip pain with a limp Often follows URI Resolves in 1-2 weeks Treat with antibiotics |
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What musculoskeletal disease is often preceded by an upper respiratory tract infection
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Transient synovitis
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Describe septic arthritis of the hip in children
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Patient looks ill and refuses to walk/bear weight on joint
Knee is very often involved STAPH and strep Treat with antibiotics |
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Describe osteomyelitis of the hip in children
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Like septic hip, except child will allow joint movement
Increased opacity and edema of affected bone on MRI |
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Describe Legg-Calve-Perthes disease in children
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Idiopathic avascular necrosis of femoral head
M>F A limp is the primary issue, less hip pain |
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Describe slipped capital femoral epiphysis in children
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Slippage of the femoral head posteriorly
Obesity association Early adolescence Patients have a limp and abnormal internal rotation of hip |
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Describe osteoid osteoma in children
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Common
Nighttime pain resolved with NSAIDs Xray - ovoid lesion w/ surrouding cortical thickening |
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Describe patellofemoral pain syndrome ("patellar tracking") in children
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Pain on anterior knee and patellar tenderness
F>M Adolescents Pain descending stairs Associated with weak quadriceps |
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Describe Osgood-Schlatter disease in children
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Repeated trauma to tibial tuberosity
Adolescent athletes M>F |
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Describe benign hypermobility syndrome
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Pain with hypermobility
Primarily at night, mainly in legs |
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Describe oligoarthritis in children
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asymmetric arthritis
Very often momoarticular at onset F>M Early childhood onset Typically in large joints May have silent uveitis and untreated can have leg asymetry |
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Describe polyarthritis in children
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Like adult RA, but doesn't spare DIPs and impacts the cervical spine
F>M Onset in late childhood RF+ and RF- varients RF- has earlier onset and less agressive |
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Describe systemic arthritis in children
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Quotidian fever
Small, discrete, salmon-colored flat spot rash primarily on trunk that is not pruritic Diagnosis based on fever, rash, lymphadenopathy, hepatomegaly, splenomegaly, serosistis |
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Describe enthesitis related arthritis in children
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Seronegative spondyloarthropathies
Suspected with arthritis in male over 6yo and family history of spondyloarthritis, anterior uveitis, or sacroiliitis with IBD |
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A 7yo male with arthritis and a family history of spondyloarthritis, anterior uveitis, or sacroiliitis with IBD might be suspected of having
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Enthesitis related arthritis
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Describe juvenile scleroderma
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Usually localized
Usually linear with a red, itchy, scaly border and hypopigmented center that can extend to bone possible "coup de sabre" |
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What are the general features of seronegative spondyloarthropathies
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Absence of RF
Associated with HLA-B27 Insidious onset of inflammatory spinal pain with morning stiffness Uveitis, lower back pain/sacroiliitis, enthesitis, dactylitis Treat with NSAIDs, anti-TNF, SSZ, and steroids |
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Enthesitis is
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Inflammation where tendon, ligament, or fascia insert into bone
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What are the clinical aspects of ankylosing spondylitis
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Enthesitis
Back pain from sacroiliac joint Girdle (hips and shoulders) might be involved and hip pain might be primary symptom Fatigue, weight loss, acute anterior uveitis, risk of spine fracture |
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What are some physical exams for ankylosing spondylitis
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Shober test - forward flexion increasing length of lower back curve
Chest expansion below breasts C-spine - distance between occiput and wall |
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What is seen on imaging of ankylosing spondylitis
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Bamboo spine
Sacroiliitis Calcification of anterior longitudinal ligament |
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Reactive arthritis is caused by what
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1-3 weeks after venereal infections or gastroenteritis
- Chlamydia, shigella, salmonella, yersinia, campylobacter |
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What are the clinical aspects of reactive arthritis
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Asymmetric lower extremity arthritis
Enthesitis Pleurisy Conjunctivitis Urethritis Circinate balanitis Keratoderma blennorrhagica Oral ulcer GI inflammation like Crohns |
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What are the possible clinical courses in reactive arthritis
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Monocyclic
Polycyclic Chronic progressive Severe mutilans |
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How are skin and eye problems in reactive arthritis treated
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Skin - methotrexate, retinoids, phototherapy
Eye - Topical steroids, mydriatics, cycloplegics |
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What is seen on radiologic examination of psoriatic arthritis
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Erosive changes and new bone at distal joints (pencil in cup)
C-spine involvement Marginal syndesmophytes Asymmetric features |
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What are the clinical features of psoriatic arthritis
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Many patterns
Possible spondyloarthropathy Less tender than RA Unilateral sacroiliitis Nail lesions |
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Describe enteropathic arthritis
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Due to GI problems (Crohns and UC)
Axial arthritis (similar to AS) Peripheral joint arthritis (Crohns, coincide with gut activity) Clubbing or uveitis Can use azathioprine |
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What is Forestier's disease (DISH)
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Diffuse Idiopathic Skeletal Hyperostosis
Sparing of sacroiliac joints The osteophytes that form are less smooth/symmetric Classically has right sided thoracic vertebral body ossification |
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Describe seborrheic keratosis
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Benign tumor
Greasy "stuck on" papule that flakes when scratched Pseudo-horn cysts |
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What is Stucco keratosis
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A benign skin tumor like seborrheic keratosis
Whiter than SK On lower extremities of elderly patients |
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What is dermatosis papulosis nigricans
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A benign tumor of the skin, subtype of SK
Many small SKs on cheek/temple More common in African Americans |
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Describe basal cell carcinoma
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Most common skin malignancy
Rarely metastasize Mutation of PTCH Pearly pink papules with a rolled border overlying telangiectasias Rounded nests of basaloid cells, peripheral palisading, clefts |
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A pearly pink papule with a rolled border overlying telangiectasias might be a lesion associated with what
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Basal cell carcinoma
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Describe the appearance of squamous cell carcinoma
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Pink/red indurated crusted papules or a scaly non-healing patch
Large, intact cells at surface of skin Keratin pearls |
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Describe actinic keratosis
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A precancerous lesion that can progress to SCC
Rogh scaly pink macule that feels like sandpaper |
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Describe an ephelis
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Freckle
Red-brown macule Increased melanin in basal layer NO increase in melanocytes NO elongation of rete ridges |
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Describe a solar (senile) lentigo
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Brown macule from sun damage
Increased melanin at base YES elongated rete ridges |
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Describe a Nevus in general
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A mole
Aggregate of melanocytes throughout rete ridges |
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What are the types of nevus
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Congenital
Acquired Atypical |
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Describe a melanoma
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Most malignant skin tumor
ABCDEs Treat with surgical excision |
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What is the most important prognostic factor of a melanoma
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Breslow depth (of invasion)
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Describe a sebaceous hyperplasia
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Yellow umbilicated papules
See prominent sebaceous gland lobules surrounding a dilated hair follicle |
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Describe the histologic appearance of a lipoma
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Encapsulated, lobulated, and lacking the fibrous septae of normal tissue
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Describe a neurofibroma
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Soft, pink-white nodule with "button-hole sign"
Many spindle cells within dermis and mast cells |
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Describe an epidermoid cyst
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Most common cutaneous cyst primarily on face and upper trunk
Due to plugging of a follicular orifice A compressible nodule with central punctum full of a cheesy white pungent material |
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Describe a pilar cyst
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Like EIC, no punctum, no discharge
Contains keratin 90% occur on scalp |
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Describe the etiology of a lichen planus
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Idiopathic inflammation from basal cell damage
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Describe the microscopic characteristics of lichen planus
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Compact hyperkeratosis
Wedge shaped hypergranulosis Epidermal acanthosis with saw tooth rete ridges Basal cell damage resulting in dyskeratotic keratinocytes Band-like lymphocytic infiltrates |
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Describe the primary lesion of lichen planus
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4Ps
Purple Polygonal Pruritic Papule (flat topped) |
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What is psoriasis
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Chronic, recurrent, inflammatory disease characterized by well-demarcated, pink plaques with silvery scales
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What are the microscopic characteristics of psoriasis
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Hyperkeratosis and parakeratosis
Neutrophils within stratum corneum and spinosum Regular epidermal hyperplasia with thickened corneum Dilated capillary loops Dermal inflammatory infiltration by lymphocytes and neutrophils |
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What is a proposed mechanism for the pathogenesis of psoriasis
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Th1 mediated release of cytokines (TNF)
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What drugs can make psoriasis worse
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Lithium
Beta blockers NSAIDs |
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What is Auspitz sign
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pinpoint bleeding occurring as scales of psoriasis are scraped off
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What psoriasis variant is associated with strep infection
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Guttate
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Spongiotic dermatitis displays what
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intraepithelial vesicles
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What are the types of spongiotic/eczematous inflammatory dermatoses
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Atopic dermatitis
Contact dermatitis Seborrheic dermatitis |
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Describe the morphology of atopic dermatitis
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Erythematous and papulovesicular
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Describe the morphology of contact dermatitis
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Erythematous and scaling
+/- fissures and lichenification |
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What is the triad associated with atopic dermatitis
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Atopic dermatitis
Allergic rhinitis Asthma |
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Describe some clinical features of atopic dermatitis
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IgE elevation
STRONG pruritis <18mo - extensor associated >2yo flexor associated Prone to secondary infection with staph or virus |
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What are the types of contact dermatitis
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Irritant
Allergic |
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Describe seborrheic dermatitis
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Possibly from overgrowth of pityrosporum
Infantile often involves ears and neck Adult typically involves scalp, face, neck, and upper chest |
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What are the types of vesiculobullous dermatoses
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Pemphigus vulgaris
Bullous pemphigoid |
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Describe Pemphigus vulgaris
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Intraepidermal involvement (blister)
Autoantibodies against desmoglein Anthylosis Tomb stone formation Erosions Fishnet pattern on immunofluorescence |
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Describe bullous pemphigoid
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Subepidermal bullae
Autoantibodies against basal hemidesmosomes Blisters Linear pattern on immunofluorescence |
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Describe granuloma annulare
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Idiopathic chronic granulomatous inflammation
Necrobiosis (granuloma with central collagen with mucin deposition) Localized and Generalized types |
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Describe localized and generalized appearances of grauloma annulare
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Localized - Pink-purple thinly bordered annular papules and plaques on hand and feet
Generalized - Diffuse, symmetric, papular or annular with 10-100s of lesions on neck, trunk, and upper extremities |
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Describe the main/general feature of panniculitis
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Inflammation of subcutaneous tissue
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Describe erythema nodosum
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Painful, erythematous, non-ulcerated deep nodules
Often on anterior tibial surface Progresses from bright red to brown-yellow Many causes |
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Alopecia areata may be associated with
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vitiligo
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Malassezia furfur causes...
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Tinea versicolor
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Describe the appearance of the lesions caused by molluscum contagiosum
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Flesh colored dome shaped umbilicated papules/nodules
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Type 1 "Postmenopausal" osteoporosis will be benefited by what type of therapies
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Antiresorptive therapies
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Types 2 "Senile" osteoporosis will be benefited by what therapies
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Bone formation therapies
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Bisphosphonates can be used for what (and how do they function)
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Treating osteoporosis
Act on FPP synthetase to decrease the ability of osteoclasts to attach to bone by disrupting their membranes |
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Denosumab is used for what and how does it work
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Treats osteoporosis
Antibody that stimulates fxn of osteoprotegerin to inhibit differentiation of osteoclast progenitors into osteoclasts |
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What are the stages of gout
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Asymptomatic hyperuricemia
Acute intermittent gout Intercritical gout Chronic tophaceous gout |
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What is the presumptive triad for the diagnosis of gout
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Acute monoarticular arthritis
Hyperuricemia Good colchicine response |
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Monosodium urate crystals have what appearance in lab relevant analysis
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Needle shaped crystal
Strong negative birefringence under polarized light (yellow) |
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Gout might have what radiographic appearance
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Erosions with an overhanging edge "rat-bite" appearance with preserved joint space
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How is acute gout treated
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Anti-inflammatory
NOT anti-hyperuricemic |
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How is chronic gout treated
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Anti-hyperuremics:
Xanthine oxidase inhibitor (allopurinol) Uricosuric agents Pegloticase |
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CPPD deposition disease is associated with what other metabolic diseases in particular
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Hyperparathyroid disease
Hemochromatosis |
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CPPD crystals have what appearance in lab relevant analysis
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Rhomboid/rod-shaped
Weak positive birefringence (blue) under polarized light |
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CPPD deposition disease classically affects what joints
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Large joints, especially the knee
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BCP disease... DESCRIBE IT NOW!!!
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Calcium deposition can be seen
Milwaukee shoulder Calcific periarthritis |
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Describe subacute lupus erythematosus
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Typically 15-40yo
Non-scarring, photo-distributed, scaly, erythematous psoriasiform or annular plaques Can cause lupus like issues in fetus |
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Describe discoid lupus erythematosus
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Scarring photo-distributed rash of dull red macules/plaques
Adherent scale Heals with atrophy, dyspigmentation, and telangiectasias |
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Describe the skin manifestations of dermatomyositis
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Heliotrope rash, Gottron's papules
Photodistribution with capillary loops |
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Describe the skin manifestations of CREST
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Calcinosis, Raynaud's, Sclerodactyly, Telangiectasias
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Describe a heliotrope rash
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Eyelids swollen and pink/purple rash
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Describe Gottron's papules
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Red/purple scaling eruption over knuckles, knees, and elbows
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Taut skin and a decreased oral aperture with a "neck sign" is indicative of what
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Progressive Systemic Sclerosis
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What are the differences between phototoxic and photo-allergic drug reactions
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Photo-toxic: No prior exposure, looks like sunburn
Photo-allergic: Prior exposure required, looks like a rash |
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Hepatitis C has what skin signs
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Cryglobulinemia (leukocytoclastic vasculitis)
Telangiectasias PAN Lichen planus Porphyria cutanea tarda Necrolytic acral erythema |
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Describe lyme disease
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Primary (erythema chronicum migrans) - bull's eye
Secondary - Bell's palsy, pericarditis Tertiary - acrodermatitis chronica atrophicans - purple acral plaques --> shiny cigarette paper atrophic plaques |
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Describe rocky mountain spotted fever
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Petichial eruption with centripital spread
Fever Large pink-purple rash Treat with doxycycline |
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Describe the skin lesions of blastomycosis
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Papulopustules or verrucous plaques
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Describe the skin lesions of cryptococcosis
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Molluscum-like lesions on face
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Describe the skin lesions of fusarium
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Vesiculonecrotic lesions
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What skin lesions are associated with small vessel disease
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Uticarial lesions and palpable purpura
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What skin lesions are associated with small artery disease
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Subcutaneous nodules
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What skin lesions are associated with medium artery disease
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Necrosis of major organs
livedo reticularis Purpura |
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What is Livedo reticularis
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Lace-like purplish discoloration of skin
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What skin lesions are associated with large artery disease
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Claudication and necrosis
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Memorize the Leukocytoclastic vasculitis mnemonic
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VASCULITIS
Remember it!!! |
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Endocarditis has what lesions resulting from septic emboli
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Janeway lesions
Roth spots Osler's nodes |
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What are Janeway lesions
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Endocarditis associated non-tender purpuric macules on palms and soles
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What are Roth spots
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Endocarditis associated retinal hemorrhages with pale or yellow centers
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What are Osler's nodes
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Endocarditis associated immune complexes causing the formation of tender purpuric lesions
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Describe Necrobiosis Lipoidica Diabeticorum
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Collagen degeneration with a granulomatous response
Asymptomatic shiny patches that slowly enlarge Depressed atrophic plaques that can ulcerate |
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Describe diabetic dermopathy
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Changes in small vessels with small blood leakage
Light brown, oval, slightly indented scaly patches "Pretibial pigmented patches" |
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Describe acanthosis nigricans
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Hyperpigmented, velvety plaques on face, neck, axilla, and groin
Associated with malignancy, obesity, and diabetes |
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Describe acrodermatitis enteropathica
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sever zinc deficiency
Scaly erythematous, eczematous, macerated/erosive plaque |
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Describe hereditary hemorrhagic telangiectasia
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Dilated capillaries
Often appears on tongue and nose Can have nose-bleeds and melena |
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Sign of leser-trelat is associated with what
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Adenocarcinomas of stomach and colon
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How does sign of leser-trelat appear
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Large eroptions of seborrheic keratosis +/- acanthosis nigricans
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Paraneoplastic pemphigus is associated with what
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Blistering of mucosae
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What are the two neutrophilic dermatosis
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Sweet's Syndrome
Pyoderma Gangrenosum |
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Describe Sweet's Syndrome
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Acute febrile neutrophilic dermatosis
"Juicy plaques" |
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Describe pyoderma gangrenosum
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Begins as inflammatory pustule with surrounding halo that can ulcerate
Associated with IBD Appears like a systemic fungal infection |
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What are the most common causes of drug induced skin reactions
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Aminopenicillins, sulfonamides, and NSAIDs (also anticonvulsants)
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What are the Seven "I"s
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Drug history mneominc
Instilled Inhaled Ingested Inserted Injected Incognito Intermittent |
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Immediate type drug reaction have what skin manifestations
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Uticaria
Angioedema Anaphylaxis |
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Delayed type drug reactions have what skin manifestations
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Exanthematous Drug Eruption
Fixed Drug Reactions Drug-Induced Hypersensitivity Syndrome Stevens Johnson Syndrome Toxic Epidermal Necrolysis Erythema Multiforme |
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What is the most common delayed type skin manifestation of drug reaction
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Exanthemous Drug Eruption
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Describe the presentation of exanthematous drug eruption
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Small erythematous papules and macules coalescing into patches and plaques
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Describe the presentation of fixed drug reactions
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Solitary erythematous patch that occurs in the same spot on re-exposure
Often on face, and oral and genital mucosa May blister and erode |
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HLA-B22 may increase the risk of what type of skin disease
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Fixed drug reaction
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Describe drug-induced hypersensitivity syndrome
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Eosinophilia, DRESS, and increased IL-5
Rash and facial edema and fever May persist long after exposure ends |
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Describe Stevens Johnson Syndrome
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Erythema multiforme with oral mucosa involvement and fever
Painful Blisters break to reveal red, oozing dermis |
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Describe toxic epidermal necrolysis
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Severe form of SJS
Diffuse sloughing of skin resembling a large burn |
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Describe erythema multiforme
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Associated with HSV, mycoplasma, drugs, AI, and malignancy
Hypersensitivity rxn with targetoid rash and bullae Central epidermal necrosis surrounded by erythema |
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Describe cellulitis
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Dermal/subcutaneous infection beginning from wound, insect bite, or fungal infection
Staph, or strep pyogenes Red, tender, swollen rash w/ fever Can progress to necrotizing fasciitis, sepsis and death |
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Describe erysipelas
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Superficial cellulitis involving dermal lymphatics
Beta-hemolytic strep Characteristic raised indurations |
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What are the medium vessel vasculitises
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Polyarteritis nodosa
Kawasaki's disease |
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What are the large vessel vasculitises
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Giant Cell Arteritis
Takayasu's Arteritis |
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What are the ANCA associated small vessel vasculitises
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Wegener's granulomatosis (Granulomatosis with polyangiitis)
Churg-Strauss Syndrome Microscopic Polyangiitis |
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What are the Non-ANCA small vessel vasculitises
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HSP
Essential Mixed Cryoglobulinemia Bechet's Syndrome |
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Describe PAN and its clinical features
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Necrotizing vasculitis that spares the lungs
Hypertension, abdominal pain with melena and painful rash on ankles and fingers Livedo reticularis Associated with Hep B |
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Describe Kawasaki's Disease
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Asian children <5yo
Erythematous rash on palms and soles Dry cracked lips and peeling fingertips Leading cause of acquired heart disease in children Thrombocytosis and hypoalbuminemia |
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Describe GCA
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Granulomatous inflammation around branches of carotid arteries
Older adults Flu-like presentation Risk of blindness Inflamed vessel wall with giant cells |
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Describe Takayasu's arteritis
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Granulomatous inflammation of aortic arch at branch points
Adults <50yo (Young, asian females) Weak/absent pulse in upper extremities New onset HTN |
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Describe Wegener's Granulomatosis
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Necrotizing granulomas in nasopharynx, lungs, and kidneys
Sinusitis, hemoptysis, hematuria Skin nodules in crops Hypertrophic gingivitis (Strawberry gums) c-ANCA - anti-proteinase 3 |
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Describe Churg-Strauss Syndrome
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Necrotizing granulomatous inflammation with eosinophils
Lots of heart and lung involvement ASTHMA p-ANCA - anti-MPO |
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Describe microscopic polyangiitis
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Necrotizing vasculitis - lungs and kidneys
Like Wegener's, but without nasopharyngeal involvement p-ANCA - anti-MPO |
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Describe HSP
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IgA immune complex deposition
Buttocks and legs - palpable purpura GI pain and bleeding Hematuria Often follows URI |
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Essential Mixed Cryoglobulinemia is associated with what
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Hep C
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Describe Bechet's Syndrome
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Seen after viral infection
Recurrent oral, nasal, and genital ulcers More common in mediterranean descent More aggressive in males |
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Polymyositis presents with what
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Proximal muscle weakness
Elevated CK Endomysial inflammation due to CD8+ t-cells |
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Dermatomyositis presents with what
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Proximal muscle weakness
Elevated CK Perimysial inflammation due to CD4+ t-cells |
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What types of rash are associated with dermatomyositis
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Heliotrope rash
Gottron's papules Malar rash |
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What antibody is associated with dermatomyositis
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Anti-jo-1
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Dermatomyositis is associated with what cancer
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Gastric carcinoma
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Describe statin associated myopathy
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HMG-CoA reductase inhibitors
Increased serum CK Myalgias, muscle tenderness and weakness occur |
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What markers are associated with Sjogren's
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RF+
ANA+ SSA and/or SSB |
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Patients with Sjogren's are at risk for developing what other disease
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B-cell lymphoma (esp MALT)
Oral candidiasis PBC association |
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Describe diffuse systemic scleroderma
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Proximal skin thickening
Rapid onset Involves lungs, heart, GI, and/or kidneys Poor prognosis **Anti-topoisomerase** (Anti-Scl70) |
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Describe limited systemic scleroderma
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Symmetric distal skin thickening
Slow progression Less severe CREST **Anti-centromere** |
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Describe the skin involvement of systemic scleroderma
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Puffy hands and fingers
Pruritis Hyperpigmentation Telangiectasias Calcinosis Digital ulcers |
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What are the classification criteria for SLE
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I'M DAMN SHARP
Immunoglobulins Malar rash Discoid rash Antinuclear antibody Mucositis Neurologic disorders Serositis Hematologic disorders Arthritis Renal disorders Photosensitivity |
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What are the immunoglobulins associated with SLE
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anti-dsDNA
anti-Smith anti-histone (drug induced lupus-like) anti-SSA or SSB anti-ribosomal phosphoproteins ANA |
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What are the drug treatments for the arthralgias associated with SLE
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Hydroxychloroquinone
Methotrexate Belimumab |
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The primary problem in osteoarthritis is what
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Cartilage degeneration at stress points leading to further degradation of the joint
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Heberden's nodes and Bouchard's nodes are features of what disease
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Osteoarthritis
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Is the joint space narrowing of osteoarthritis uniform or non-uniform
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Non-uniform
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What is gull-wing deformity
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A feature of erosive OA
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RA presents with what (relating to joints)
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Symmetric synovitis with bone erosion at joint margins
Bone edema and flexor tenosynovitis |
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Felty's syndrome is what
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The triad of:
RA Splenomegaly Neutropenia |
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RA is associated with what labs
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RF+
anti-CCP Normochromic normocytic anemia 5k-25k WBCs/mm3, highly PMN |
