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32 Cards in this Set

  • Front
  • Back
What are the 4 basic levels of sleep:
1) Wakefulness
2) Slow-Wave sleep (4 stages)
3) REM
4) Coma
At what point would a EEG exhibit a discharge of
High frequency
Low amplitude
During an awake and alert state or REM sleep
What sort of waves are at a frequency of 8-13/sec and are observed whence eyes are closed?
alpha waves
Low frequency, low amplitude waves:
what are they called?
what is their rate?
and what stage are they observed in?
-Theta waves
-4-7/sec
-Stage 1 (slow wave sleep
When is cortical firing coordinated rather than acting individually?
during sleep
What are sleep spindles and in what stage are they observed?
Intermittent, higher amplitude higher frequency alpha waves
Stage II
Slow waves of increasing amplitude with frequency (<5/sec) and what stage are they present?
Delta waves
at what stage of sleep is bruxism common?
REM
how much of an adult's sleeping cycle is spent in the REM stage?
15-20%
how much of an infants sleeping cycle is spent in the REM stage?
50%
Low serotonin levels resemble what phenomenon of sleep?
dreaming
What is a serotonergic transmission source in the brain that stimulates the early stages of sleep?
Dorsal Raphe nucleus
During REM sleep what regions of the brain are most active and slowed?
Locus Coerulus - active firing
Dorsal Raphe nucleus - low activity
What is the transmission of the Locus Coerulus?
Noradrenergic
High Norepinephrine
Low Serotonin
REM
What drug inhibits the Dorsal Raphe nucleus?
LSD (Lysergic Acid Diethylamide)
What region is important in arousal from sleep?
Reticular Formation of RAS (Reticular Activating System)
what is demonstrated as the relay center for the midbrain --> cortex that can produce Theta waves
NST (Non-Specific Thalamic Nuclei)
Lesion to the brainstem reticular formation results in?
Delta wave production blocking any arousal sensory input.
The inability to wake naturally by arousal is called?
Coma
What neurons comprise the RAS and thus lead to sensitization for arousal?
Gigantocellular and Tegmental fields
So the 3 consecutive regions for arousal out of sleep are?
RAS
NST
Cortex
what kind of mechanism is seen to amplify the sensitizing of the cortex to awake by stimulus from the lower regions?
Positive Feedback
Damage to the RAS would resutl in?
a Coma
what is an important Dopamine source in the brain involved with arousal?
Substantia Nigra
What part of Hypothalamus might be involved with sleep arousal?
Pineal gland
What region is involved in focusing the body to do one thing by stimulating the NST to convey this in the cortex?
Pontine Reticular Formation
The neurons of the ____ _____ inhibit RAS by Dorsal Raphe nucleus stimulation and cause one to fall asleep.
Area Prostrema
_________ is sleep walking that is observed in 1-6% of the population and is seen in what stages of sleep____?
Sonambulism
3/4
A severe nightmare occuring during Stage 4 sleep for 1-2 min?
Night Terrors
What is an example of Sleep apnea in children?
SIDS (Sudden Infant Death Syndrome)
A sudden sleep attack accompanied by:
cataplexy
sleep paralysis
hypnogogic hallucinations
Narcolepsy