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19 Cards in this Set
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Superficial, Cutaneous, and Subcutaneous Fungal Infections
Lecture 1 Dugan 5/4/09 |
Superficial, Cutaneous, and Subcutaneous Fungal Infections
Lecture 1 Dugan 5/4/09 |
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1,2Q:
Pityriasis Versicolor |
Organism: Malassezia furfur
-on outermost layer of dead skin - normal flora on humans -no inflammatory response -likes sweat (sebum)--> armpits, groin -doesn't use keratin for growth -shows up when sunburned |
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1,2Q:
Name three superficial fungal infections |
Pitiriasis vesicolor,
tinea nigra, black piedra/white piedra |
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1,2Q:
Tenia Nigra |
Organism: Exophiala weneckii
-same characteristics as malassezia but produces a dark pigment -resembles melanoma -likes keratin tx: salicylic acid, benzoic acid |
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1,2Q:
Spaghetti and Meatballs |
diagnosis for pityriasis versicolor
-dimorphic morphology after KOH digestion of skin scraping -use fluorescence under Wood's Lamp |
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1,2Q:
Consequence of Malassezia overgrowth |
Seborrheic Dermatitis:
Dandruff Cradle Cap *sebum overproduction and the normal flora malassezia gets trapped. |
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1,2Q:
What does DIMORPHIC mean? and give an example, please. |
grow as yeast or mold. an example is pityiasis versicolor, which looks like spaghetti and meatballs
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1,2Q:
Black piedra, White piedra |
Organism: Piedraia hortae
-really likes keratin in the hair -grow on the surface of the hair, causes black or white nodules on the hair tx: shave head, antifungal |
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1,2Q:
How do you differentiate Superficial from Cutaneous Fungal Infections? |
Superficial:
-Sweat/sebum for nutrition -non inflammatory metabolites Cutaneous: -keratin for nutrition -inflammatory metabolites |
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1,2Q:
3 major genuses of cutaneous fungal infections |
Trichophyton (most common)
Microsporum Epidermophyton *all same causation of disease **not normal flora ***communicable |
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1,2Q:
Name some cutaneous fungal infections (dermatophytoses) |
Based on where they are on the body:
Tinea corporis: ringworm of trunk and legs Tinea imbricate: concentric rings of scales over trunk, legs, forearms Tinea pedis “athlete’s foot”: scaling between toes, lateral side of the foot Tinea cruris “jock itch”: rash, scaling, inner thighs Tinea capitis: disease of children, hair loss, scaling, inflammation of the scalp skin Tinea barbae: infection of the hair and skin around the bearded areas of neck and face Tinea unguium: infection of nails, thickening, fissuring, colorization *ringworm is most common fungal infection in the US. Mostly caused by trichophyton rubrum |
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1,2Q:
Ids |
Diagnostic Papules- noninflammatory papullar eruptions (small) distant form the infection
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1,2Q:
Copper Penny Spores |
Chromoblastomycosis:
diagnostic; brown pigmented yeast form -spores implant and adapted form must grow Organism: Fonsecaea, Cladosporium -dimorphic conversion (can take up to years before symptoms) |
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1,2Q:
Rose Thorn |
Sporotrichosis:
-most common in the US. - named b/c acquired from bark of the rose bushes -ulcerative papule spread through lymphatics Oraganism: Sporothrix |
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1,2Q:
Asteroid Body |
Diagnostic for sporotrichosis:
adaption to a true yeast, multiple buds that migrate away from the lesion |
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1,2Q:
Name 3 Subcutaneous Infections |
Chromoblastomycosis (most common worldwide)
Sporotrichosis (most common in US) Mycetoma *99% fungi can't survive subcuntaneously, so these are more rare and difficult to treat **most be physically implanted into/under skin |
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1,2Q:
Mycetoma |
Madura Foot
Organism: Madurella (and pseudoallescheria) -painless papules and nodules -most destructive: sinus tracts formation will lead to spread and deeper tissue infiltratoin |
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1,2Q:
Endothrix vs Ectothrix |
Exothrix- conidia outside of hair shaft
Endothrix- conidia inside hair shaft *way to classify tinea capitis |
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1,2Q:
Condition for growth in yeast form? In hyphal form? |
yeast--37 degrees
hyphae- 25 degrees Yeast is touching the skin Hyphae is farther away |
