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19 Cards in this Set
- Front
- Back
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Streptococcus pyogenes: structural virulence factors
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Capsule
Fibrils Peptidoglycan layer T/R proteins |
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Streptococcus pyogenes: soluble virulence factors
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Streptokinase
Streptodornase Hyaluronidase Erythrogenic toxin NADase Streptolysins: Streptolysin O/S |
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Pseudomonas aeruginosa: virulence factors
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Pili
Polysaccharide capsule Endotoxin Extracellular enzymes Exotoxin A Tissue necrosis |
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general properties of streptococci
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gram +
catalase - chains |
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classification of streptococci
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C-carbohydrate (Lancefield groups)
Hemolysis of 5% sheep blood (beta, alpha, gamma) |
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localized infections caused by S. pyogenes
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pharyngitis (sore throat)
scarlet fever impetigo |
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invasive infections caused by S. pyogenes
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wounds
erysipelas cellulitis puerperal fever endocarditis |
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postinfection diseases caused by S. pyogenes
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rheumatic fever
glumerulonephritis |
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general characteristics of pseudomonas aeruginosa
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gram -
motile w/ polar flagella oxidase + obligate aerobes grow at 42 C colonies produce a fruity odor and are usually pigmented |
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Gram-negative, nonfermenter:
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pseudomonas aeruginosa
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Produce pyocyanin pigment
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Pseudomonas aeruginosa
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ecthyma gangrenosum:
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Pseudomonas aeruginosa
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Pt w/ cystic fibrosis pneumonia, colonies produce blue pigment
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Pseudomonas aeruginosa
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Other diseases caused by pseudomonas aeruginosa:
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otitis externa
folliculitis |
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Streptokinase:
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activates plasminogen, breaks down clots
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Streptodornase:
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breaks down DNA
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Hyaluronidase:
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breaks down hyaluronic acid (ground substance b/w cells)
allows organism to invade |
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Erythrogenic toxin:
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exotoxin
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Streptolysins:
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RBC's lyses
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