Skin Disorders

Front 1

Impetigo

Back 1

superficial skin infection, honey crusting, highly contagious
SA, GAS

Front 2

Dermatitis

Back 2

a group of inflammatory pruritic skin disorders; allergy (IV HS), chemical injury of infection

Front 3

Atopic dermatitis (eczema)

Back 3

pruritic eruption, commonly on flexor surfaces, often associated with other atopic disease (asthma, allergic rhinitis)

Front 4

Allergic contact dermatitis

Back 4

type IV HS reaction that follows exposure to allergen (poison ivy, poison oak, nickel, rubber, chemicals)
lesions occur at site of contact

Front 5

psoriasis

Back 5

epidermal hyperplasia (acanthosis) with parakeratotic scaling (nuclei still stratum corneum), esp on knees on elbows
increased stratum spinosum, decreased stratum granulosum; aspitz sigh
silvery scale

Front 6

Dermatitis herpetiformis

Back 6

pruritic papules and vesicles; deposits of IgA at tips of dermal papillae. Associated with celiac disease

Front 7

lichen planus

Back 7

pruritic, purple, polygonal papules; infiltrate of lymphocytes at dermoepidermal junction.

Front 8

Steven Johnson syndrome

Back 8

caused by sulfa and anticonvulsant drugs- major form of erythema multiforme. Characterized by high fever, bulla formation, and necrosis, ulceration of skin and high mortality rate

Front 9

Erythema multiforme

Back 9

Associated with infections, drugs, cancers and AI disease. Presents with multiple types of lesions, including macules, papules and vesicles and target lesions (red papules with a pale central area)

Front 10

seborrheic keratosis

Back 10

flat, pigmented squamous epithelial proliferation with keratin-filled cysts (horn cysts) benign

Front 11

actinic keratosis

Back 11

caused by sun expsoure; small rough erythematous or brown papules. Premalignant lesion. Risk of carcinoma is proportional to epithelial dysplasia

Front 12

keloid

Back 12

tumor of connective tissue elements of dermis that causes raised, thickened scars. Follows trauma to skin, especially in AA
tx: intralesional steroids to thin the skin

Front 13

Bullous pemphigoid

Back 13

AI disorder with IgG antibody against epidermal basement membrane hemidesmosomes (linear IF). Similar to but less severe than pemphigous vulgaris- affects skin but spares oral mucosa

Front 14

Pemphigus vulgaris

Back 14

potental fatal AI skin disorder. Intraepidermal bullae involving oral mucosa and skin. Findings: acatholysis (breakdown of epithelial cell to cell junctions), IgG antibody against epidermal cell surface desmosomes (IF throughout epidermis)

Front 15

Verrucae (warts)

Back 15

soft tan colored cauliflower like lesions. epidermal hyperplasia, hyperkeratosis, kiolocytes
verruca vulgaris on hands, condyloma acuminatum on gentials

Front 16

sq cell carcinoma

Back 16

very common; associated with excessive sun exps and arsenic. commonly appear on hands and face. locally invasive but rare mets. see keratin pearls
precusor: actinic keratosis

Front 17

basal cell carcinoma

Back 17

most common in sun exps areas. locally invasive but rare mets. see pearly papules
shiny dome
telangiectasias, palisading nuclei

Front 18

melanoma

Back 18

common tumor with significant risk of mets; associated with sunlight expsoure; fair skinned persons at increased risk. incidence high. depth of tumor correlates with risk of mets

Front 19

acne

Back 19

hyperkeratosis, sebum overproduction, proprionibacterium acnes proliferation, inflammation
tx: topical vit A, estrogens, steroids, isotrenitoin (accutane), benzoyl peroxide, topical/oral AB