Skin Disorders

Front 1

multiple lesions blending together

Back 1

confluent or coalescent

Front 2

flat discoloration < 1cm

Back 2

macule

Front 3

circumscribed area of skin edema

Back 3

wheal

Front 4

narrow linear crack into epidermis, exposing dermis

Back 4

fissure

Front 5

vesicle-like lesion with purulent content

Back 5

pustule

Front 6

flat discoloration >1cm

Back 6

patch

Front 7

raised lesion, >1cm, may be same or different color from surrounding skin

Back 7

plaque

Front 8

netlike cluster

Back 8

reticular

Front 9

loss of epidermis and dermis

Back 9

ulcer

Front 10

loss of skin markings and full skin thickness

Back 10

atrophy

Front 11

skin thickening usually found over pruritic or friction areas

Back 11

lichenification

Front 12

in a ring formation

Back 12

annular

Front 13

Grams of topical cream or ointment needed for a single application to the hands?

Back 13

2g

Front 14

Grams of topical cream or ointment needed for a single application to an arm?

Back 14

3g

Front 15

Grams of topical cream or ointment needed for a single application to the entire body?

Back 15

30-60g

Front 16

example of a patch:

Back 16

vitiligo

Front 17

example of a papule:

Back 17

raised nevus

Front 18

example of vesicle:

Back 18

varicella (fluid-filled, <1cm)

Front 19

example of purpura:

Back 19

petechiae, ecchymosis (lesions caused by RBCs leaving circulation and becoming trapped in skin)

Front 20

example of nodule:

Back 20

epidermal cyst (raised lesion, >1cm, usually mobile)

Front 21

example of excoriation:

Back 21

pruritic skin disease (marks made by scratching)

Front 22

greatest topical med. absorption from which part of the body?

Back 22

face

Front 23

topical medication vehicle with maximum absorption?

Back 23

ointment

Front 24

most permeable skin of body for topical med absorption:

Back 24

face, axillae, genital (palms and soles are almost non-absorbable)

Front 25

amount of topical med in grams needed for one application to a leg:

Back 25

6g

Front 26

topical corticosteroids:

Back 26

are vasoconstrictive (their potency is based upon this), anti-inflammatory, immunosuppressive; best applied and covered with occlusive dressing

Front 27

low potency topical corticosteroids:

Back 27

hydrocortisone (0.5%, 1%, 2%)
triamcinolone acetonide 0.01%

Front 28

mid-range topical corticosteroids:

Back 28

betamehtasone dipropionate, augmented 0.05%

Front 29

high potency topical corticosteroids:

Back 29

fluocinolone acetonide 0.2%

Front 30

Super-High potency topical corticosteroids:

Back 30

betamethasone dipropionate 0.05% ointment or gel

Front 31

antihistmines MoA:

Back 31

block activity at histamine-1 receptor sites

Front 32

Low potency topical corticosteroids:

Back 32

hydrocortisone 0.5%, 1%, 2%

Front 33

midrange potency topical corticosteroids:

Back 33

betamethasone dipropionate, augmented 0.05%

Front 34

High potency topical corticosteroids:

Back 34

fluocinolone acetonide 0.2%

Front 35

super-high potency topical corticosteroids

Back 35

betamethasone dipropionate, augmented 0.05%, gel, ointment

Front 36

1st gen antihistamines:

Back 36

cross BBB readily, sedation and other anticholinergics effects: drying of secretions, visual changes, urinary retention

Front 37

causative agent in non-bullous impetigo:

Back 37

GABHS, Staph Aureus

Front 38

mupirocin / Bactroban spectrum is:

Back 38

select G+

Front 39

common oral antibiotic for tx of MRSA cutaneous infection:

Back 39

TMP-SMX

Front 40

At what point can a child with impetigo return to school after beginning antimicrobials?

Back 40

24 hours

Front 41

impetigo:

Back 41

peak in 2-5y/o; usually GABSA or Staph Aureus; localized; bullous type from S. Aureus; non-bullous type from Streptococcus; improve personal hygiene; mean duration 10d; tx for small topical area with mupirocin / Bactroban; tx for numerous lesions PO dicloxacillin, 1st or 2nd gen cephalosporin, azithromycin or clarithromycin (all are stable in presence of beta-lactamase; good against G+)

Front 42

MRSA immune to % of mupirocin:

Back 42

50% resistance

Front 43

in case of erythromycin resistant strains of S. Aureus and S. pyogenies use:

Back 43

HG TMP-SMX and clindamycin

Front 44

Lithium contributes to:

Back 44

acne vulgaris

Front 45

acne lesions that respond best to topical antibiotics are:

Back 45

inflammatory lesions

Front 46

tx of rosacea:

Back 46

metronidazole gel / MetroGel

Front 47

best candidate for isotretinoin / Accutane:

Back 47

cystic lesions who has used various therapies with little effect

Front 48

follow which labs with isotretinoin use:

Back 48

pregnancy status, hepatic enzymes, TG's
always ask about suicideality / depression change

Front 49

acne vulgaris:

Back 49

Propionibacterium acnes overgrowth leading to inflammatory reaction

Front 50

tx of acne vulgaris, benzoyl peroxide:

Back 50

benzoyl peroxide: low risk of skin irritation; agains P. acnes; usually with a topical antibiotic

Front 51

tx of acne vulgaris with tretinoin / Retin-A:

Back 51

increases epidermal cell turnover, transforms closed to open comedones; takes 6 weeks, photosensitizing

Front 52

tx of acne vulgaris with oral abx:

Back 52

clindamycin, erythromycin (macrolides), tetracycline (tetracyclines), azithromycin (, etc.; for moderate papular inflammatory acne; often needed long-term

Front 53

tx of acne vulgaris with topical abx:

Back 53

clindamycin, erythromycin, tetracycline; against P acnes, anti-inflammatory; for mild-moderate inflammatory acne vulgaris; less effective than oral abx

Front 54

OCP use in tx of acne:

Back 54

reduction in ovarian androgen production, decreased sebum production

Front 55

tx of acne vulgaris with isotretinoin / Accutane:

Back 55

inhibits sebaceous gland function, for tx of non-responsive CYSTIC acne; 4-6m; many SE's: cheilitis, conjunctivitis, hypertriglyceridemia, xerosis, photsenstiviity, TERATOGEN; women must use 2 birth control methods

Front 56

SE's of isotretinoin / Accutane:

Back 56

pseudo tumor cerebri. altered mood, suicideality, cheilitis, conjunctivitis, hypertriglyceridemia, xerosis, photsenstiviity, TERATOGEN; women must use 2 birth control methods

Front 57

acne-inducing medications:

Back 57

lithium and phenytoin / Dilantin

Front 58

tx of cat bite:

Back 58

Pasteurella multocida: oral amox-clavulante 500-125 3xd OR cefuroxime 0.5 g 2xd

Front 59

1st degree burn:

Back 59

affected sin blanches with ease

Front 60

2nd degree burn:

Back 60

blisters and a raw, moist surface

Front 61

3rd degree burn:

Back 61

white and leathery surface

Front 62

anterior head % of skin surface:

Back 62

4.5%

Front 63

posterior torso % of skin surface:

Back 63

10%

Front 64

anterior thigh % of skin surface:

Back 64

9%

Front 65

palmar surface BSA measurement is approximately %?

Back 65

1%

Front 66

traits of a burn that can be treated outpatient include:

Back 66

small (<10% BSA), minor (2nd degree or less), NOT a high-functioning area such as the hand or foot, of less cosmetic consequence (not the face or head)

Front 67

tx of outpatient burns:

Back 67

topical abx like mafenide acetate / Sulfamylon or silver suladiazine / Silvadene; petroleum gauze dressing

Front 68

Rule of Nines:

Back 68

for estimating BSA affected by burn; ant arm 4.5%, post arm 4.5%, ant thigh 9%, post thigh9%, ant head 4.5%, post head 4.5%, ant toss 10%, post torso 10%, palmar hand 1%

Front 69

atopic derm:

Back 69

Type I hypersens. reaction (IgE Abs occupy receptor sites on mast cells to release histamine), apply Lubricants!, COMMON SITES: flexor surfaces on adults; face on infants

Front 70

tx for atopic derm:

Back 70

pimecrolimus / Elidel: topical immunomodulator (block T-Cell stim. by APC's and inhibit mast cell activation); increase CA risk; acute: interned-potency topical corticosteroid; cool, wet dressings, avoid offending agents; in Atop Derm, the pruritus is often worse than the pain; give antihistamine at night to aid in sleep --> hydorxyzine / Atarax (Cetirizine / Zyrtec is a less sedating metabolite of hydroxyzine)

Front 71

atopic derm also has increased incidence of which diseases?

Back 71

allergic rhinitis, allergic gastroenteropathy, allergy-based asthma

Front 72

atopic derm AKA

Back 72

eczema