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52 Cards in this Set
- Front
- Back
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Layers of the skin
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S.basalis
S.spinosum S.granulosum S/coreum |
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Stem cell division occurs in this layer
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S.Basalis
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site for superficial dermatophyte infections
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S.corneum
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Dermis consist of what layers
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Papillary(loose CT beneath epidermis)
Reticular (dense dermal collagen) |
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Melanocytes are derived from
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Neural crest cells
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steps of melanin synthesis
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Tyrosinase converts Tyrosin ---> 3,4-dihydroxyphenylalanine(DOPA)-->converted to Melanin
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Define: MACULE,PAPULE,NODULE
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Macule: Pigmented or erythematous flat lesions on epidermis
Papule:Peaked or dome-shaped lesion <5mm in diameter Nodule: Elevated,dome shaped lesion >5mm in diameter |
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Define:PLAQUE,VESICLE,BULLA
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Plaque: flattned,elevated area on epidermis
Vesicle:fulid-filled blister < 5mm in diameter Bulla:fluid filled blister >5mm in diameter |
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Define:PUSTULE,HIVE,SCALES
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Pustule: fluid filled blister w/ inflmmatory cells
Hive: edematous,transient papule or plaque caused by infiltration of dermis by fluid Scales: excessive number of dead keratinocytes produced by abnormal keratinization |
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Common warts are caused by?
Common sites are found at? Treatment? |
Caused by HPV; DNA virus
Common sites: fingers and soles Rx: liquid nitrogen |
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Molluscum contagiosum is caused by? looks like? transmission? RX?
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Caused by poxvirus(dna virus)
Umbilcated lesions with viral particles Sexually transmitted(common in AIDS) Cell-mediated immunity |
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Rubeola(measles)
signs and symptoms, RX? |
Paramyxovirus(RNA)
Koplik spots develop on bucall mucosa NOT TERATOGENIC Can be prevented thru vaccination |
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What do you develop after Koplik spots disappear
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Maculopapular rash develops
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Rubella(german Measles)
Signs symptoms rx? |
RNA Togavirus
full blown in 3 days Forchheimer spots Maculopapular rash lasts 3 days |
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Erythema infectiosum(Fifth disease)
Signs and symptoms |
Caused by Parvovirus B19
occus in school age children slapped face appearance |
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Skin Infections caused by Staph Aureus
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A.skin abcess
B.Hidradenitis suppurativa C.Postsurgical wound infection D.Impetigo |
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Define Impetigo
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a contagious bacterial skin infection forming pustules and yellow, crusty sores. • This disease is caused by the bacteria Streptococcus pyogenes or S. aureus(most common cause)
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Strep Pyogenes skin infection
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scarlet fever
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Leprosy is caused by
Rx |
Mycobacterium laprae
Rx: dapsone + rifampin |
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chronic inflmmation of pilisebaceous unit
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Acne vulgaris
Rx:topical agents,hormonal terapy |
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what receptors are found in Acne Vulgaris
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Angrogen receptors located on sebaceous gland
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wheres does superficial dermatophytes live in
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Stratum corneum
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Wood's Lamp test dectes?
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Detects fluorescent fungal metabolites
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Tinea capits caused by?
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Trichophyton tonsuran #1
Negative wood's lamp Microspoirum canis and audouinni Positive wood's lam |
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Oral terbinafine; topical imidazoles dont work on what kind of tinea
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tinea capitis
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most common cause of all other tineas(except vesicolor
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T. rubrum
rx:topical agents(ex: miconazole,clotrimazole) |
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Most common tinea infection; sweating importan cause
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Tinea Pedis ("athler's foot)
rx:topical agents(ex: miconazole,clotrimazole) |
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Sweat is important pathogenis in this tenia
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Tinea Cruis ( groin, "jock itch)
Scrotum is involved rx:topical agents(ex: miconazole,clotrimazole) |
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what is Onychomycosis
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Ring worm of the nail
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Most common dermatophytes
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t.Rubrum(most) t. mentagrophytes
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You see Raised,Discoloted nail; nailpate white,thick, crumbly in this tinea
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Tenea unguium(nail,Onychomycosis)
Rx: topical agents don't work oral therapy w/ terbinafine |
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Alterations in skin pigmentation, hypopigmentation or hyperpigmentation is by
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Tinea versicolor
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T.vesicolor is caused by
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Malassezia furfur
Spaghetti and meatballs like apperance in KOH |
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Rx for t vesicolor
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topical selenium sulfide
oral ketoconazole (best treatment |
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Infections caused by Candida Albicans
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Intertrigo,Onychomycosis
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most common cause of all other tineas(except vesicolor
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T. rubrum
rx:topical agents(ex: miconazole,clotrimazole) |
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Most common tinea infection; sweating importan cause
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Tinea Pedis ("athler's foot)
rx:topical agents(ex: miconazole,clotrimazole) |
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Sweat is important pathogenis in this tenia
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Tinea Cruis ( groin, "jock itch)
Scrotum is involved rx:topical agents(ex: miconazole,clotrimazole) |
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what is Onychomycosis
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Ring worm of the nail
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Most common dermatophytes
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t.Rubrum(most) t. mentagrophytes
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You see Raised,Discoloted nail; nailpate white,thick, crumbly in this tinea
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Tenea unguium(nail,Onychomycosis)
Rx: topical agents don't work oral therapy w/ terbinafine |
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Alterations in skin pigmentation, hypopigmentation or hyperpigmentation is by
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Tinea versicolor
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T.vesicolor is caused by
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Malassezia furfur
Spaghetti and meatballs like apperance in KOH |
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Rx for t vesicolor
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topical selenium sulfide
oral ketoconazole (best treatment |
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Infections caused by Candida Albicans
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Intertrigo,Onychomycosis
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seborrheic dermatitis(dandruff) is caused by
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Malassezia furfur
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dandruff in newborns is called
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cradle cap
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Sporotrichosis is caused by
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sporothrix schenckii (rose garderner)
-subcutaneous mycotic infection -dimorphic fungus |
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Cutaneous larva migrans caused by
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ancyclostoma braziliense
-dog/cat hookworm:nematode Rx:ivermectin |
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what are chiggers
signs? |
small,red mite
cause intensly pruritic,red papular/versicular rash |
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types of lice
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pediculus humanis capitis (head louse)
Phthirus pubis (pubic louse,crabs |
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common bedbug
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cimex lectularius
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