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23 Cards in this Set
- Front
- Back
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malignancy of malanocytes
majority in skin cancer related deaths |
malignant melanoma
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MC subtype of MM
flat or slightly raised pigmented lesion |
superficial spreading MM
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subtype of MM
papulonodule, variable pigmentation, often friable (bleeds) Rapid growth |
Nodular Melanoma
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MM subtype
flat, irregular patch with eccentric atypical papule or nodule slow growth over years (older population) |
lentigo maligna melanoma
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MM subtype - least common, most common for darker skin tones
diffusion of pigment onto periungual region |
acral lentigionous
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Dx and Tx of malignant melanoma
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Dx: excisional bx when possible!!
Tx: Surgery and Sentinel node biopsy |
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non-melanoma skin cancer includes
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BCC and SCC
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most common human malignancy
slow growing excellent prognosis with therapy **Pearly papule with telangiectasias** |
BCC
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6 subtypes of BCC
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nodular
pigmented cystic superficial multifocal micronodular morpheaform |
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MC BCC
pearly or waxy erosion or ulceration, raised border |
nodular BCC
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BCC
brown or black pigment (nodular) MC in darker skins slow growing |
pigmented BCC
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BCC
transulcent cystic nodules mimic benign cysts |
Cystic BCC
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BCC
scaley patches/papules - pink to red to brown common on trunk commonly confused for eczema |
superficial BCC
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Tx for BCC
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Surgical excision - gold standard
electrodessication and curettage - ok radiation topical immunotherapy for large areas cryotherapy |
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premalignant precursor to SCC - rarely turns into cancer
scaly keratotic macules (yellow and raised) face, dorsal hands, ears, scalp |
Actinic Keratosis
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Tx for actinic keratosis
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spot therapy: LN2, dessication, spot TCA (tichloroacetic acid)
Field therapy: 5-flurouracil, imoquimod, photodynamic therapy |
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rapidly growing nodule with clinical appearance of a low grade SCC
dome-shaped papulonodule with central keratinous crater (wart core) |
Keratacanthoma
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tx for keratacanthoma
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surgery
5-flurouracil or methotrexate |
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2nd MC form of skin cancer
Men, middle age - elderly more severe, higher mortality on sun-exposed skin and cervix |
SCC
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presentation of SCC and tx
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CP: more warty than BCC, FASTER growing
Tx: surgery - gold standard, ed&c, radiation often needed, chemo, immunosuppression |
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found in older men, mediterranean origin
HHV-8 commonly occurs with HIV |
Classic Kaposi's Sarcoma
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CP of Classic kaposi's sarcoma
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purplish, reddish blue, dark brown/black lesion
macules, nodules, plaques LE often with lymphedema |
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Tx of kaposi's sarcoma
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surgery - single lesions
radiation - all forms are sensitive cyrotherapy and laser intralesional therapy - inj of chemo |
