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85 Cards in this Set

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Most common inflammatory skin disorder. Marked by intercellular edema, epidermal breakdown, three stages (acute, subacute, chronic), scratching causing crust.
Eczematous Dermatitis
Three forms of Eczema
Irritant contact dermatitis
Allergic contact dermatitis
Atopic dermatitis
Three phases of Eczema.
Acute = erythematous, pruritic, weeping vesicles
Subacute = erythema and scaling
Chronic = thick, lichenified, pruritic plaques
Atopic dermatitis
During childhood, lesions involve flexures, the nape and dorsal aspects of the limbs.

Adolescence and adulthood = lichenified plaques affect the flexures, head and neck
Inflammation and infection of the hair follicle and surrounding dermis. Follucular based pustules. Can result in scarring and permanent hair loss.
Folliculitis
Risk factors for folliculitis:
Frequent shaving, immunosuppression, dermatoses, long-term antibiotic use, occlusive clothing or dressings, hot/humid temps, diabetes mellitus, obesity, EGRF inhibitor meds
A deep seating infection of the pilosebaceous unit, that starts as a small perifollicular abscess that spreads to the surrounding dermis and subcutaneous tissue.
Furuncle (boil)
What is the most common organism that causes furuncles?
Staphylococcus aureus
Diffuse, acute, infection of the skin and subcutaneous tissue caused by Streptococcus pyogenes or S. aureus.
Cellulitis
Group of noncandidal fungal infections that involve the stratum corneum, nails or hair.
Tinea (dermatophytosis)
Tinea is caused by?
Infection by dermatophytes, acquired by direct contact with infected humans or animals. Invade the skin and survive on dead keratin.
Where does tinea corporis occur?
On nonhairy parts of the body.
Where does tiniea cruris occur?
On the groin and inner thigh
Where does tinea unguium occur?
On the nails.
How can you test for tinea hyphae?
Skin scraping treated with KOH solution.
What is a self-limiting inflammation of an unknown cause?
Pityriasis rosea
What condition has a "herald" or mother patch followed by an eruption 1-3 weeks later?
Pityriasis rosea
What is a chronic and recurrent disease of keratin synthesis, often a genetic component/immune regulation disorder?
Psoriasis
Characterized by well-circumscribed, dry, silvery, scaling papules and plaques.
Psoriasis
What is a chronic inflammatory skin disorder that lasts for years, with episodes of activity that are not itchy, but painful?
Rosacea
In what disorder can tissue hypertrophy of the nose (rhinophyma) occur?
Rosacea
What is caused by the varicella-zoster infection?
Herpes Zoster (Shingles)
What is characterized by a single dermatome consisting of red swollen plaques or vesicles that become filled with purulent fluid?
Shingles
What is characterized by a group of vesicles with an erythematous base and then erode forming a crust lasting 2-6 weeks?
Herpes simplex
Characterized by discrete or confluent erythematous macules and papules, caused by a reaction
Drug eruptions
A nonspecific reaction pattern associate with obesity, certain endocrine syndromes, or malignancies or as an inherited disorder.
Acanthosis nigricans (AN)
What is characterized by symmetric, brown thickening of the skin with plaques or patches of thickened skin with a velvety or slightly verrucous texture?
Acanothosis nigricans (AN)
What forms of acanothosis are there?
Hyperinsulinism

Inherited form (dominant)

Malignant form
Where is the most common site for acanthosis nigricans?
Armpit, other flexural areas
What is the incubation period for anthrax?
up to 12 days following deposition of organism into skin
What is characterized by a pruitic macule or papule that enlarges to a round ulcer in 2 days and is necrotic in the middle.
Anthrax
What is spread through saliva droplets?
Smallpox (variola virus)
What is the incubation period for smallpox?
12 days (7-17 days)
What does smallpox start as?
Red, flat lesions around mouth and pharynx, face and forearms. High fever, fatigue, headache, and backache.
What is the most common form of skin cancer?
Basal cell carcinoma
What is the second most common form of skin cancer?
Squamous cell carcinoma
Where does a squamous cell carcinoma arise?
In the epithelium = can become an open sore with crusting
What is the most lethal form of skin cancer and where does it arise from?
Malignant melanoma, melanocytes
What are the ABCs of melanomas?
A = Asymmetry
B = boarders
C = Color
D = Diameter
E = Evolution
What is a neoplasm of the endothelium and epithelial layer of the skin?
Kaposi's Sarcoma (herpe's virus 8)
What is Kaposki's commonly associated with?
HIV infection
Lesions are usually soft, vascular, bluish-purple, and painless
Kaposi's sarcoma
Sudden, rapid, patchy loss of hair, usually from the scalp or face, also associated with nail pitting
Alopecia Areata
What are two types of alopecia?
Scarring = destruction
Traction = prolongued tension on hair causes hair loss
Growth of terminal hair in women in the male distribution pattern on the face, body and pubic areas?
Hirsutism
What is hirsutism caused by?
High androgen levels, genetic, physiologic, drugs, systemic disorders
Inflammation of the paronychium?
Invasion of the bacteria between the nail fold and the nail plate = paronychia
Fungal infection of the nail, causing it to crumble
Onychomycosis
Caused by lateral pressure of poorly fitting shoes, improper or excessive trimming of the lateral nail plate or trauma
Ingrown nails - nail pierces the lateral nail fold and grows into the dermis
Trauma to the nail plate severe enough to cause immediate bleeding and pain, often causes seperation of the nail plate.
Subungual hematoma
What is leukonychia punctata?
White spots on the nail plate caused by minor injury or manipulation of the cuticle
What is median nail dystrophy?
Nail deformity as a result of nail picking or biting habit = horizontal sharp grooving ina band that extends to the tip of the nail
Loosening of the nail plate with separation from the nail bed that begins at the distal groove?
Onycholysis = caused by minor trauma, long fingernails, candida or pseudomonals infections, meds, allergies, hyperthyroidism
How does psoriasis affect the nails?
Pitting, onycholysis, discoloration, and sublingual thickening, yellow scaly debris elevate the nail plate, splinter hemorrhages
What are digital mucous cysts?
Cystlike structures contain a clear jelly-like substance
What are two types of digital mucous cysts?
Proximal nail fold not connected to joint space = localized fibroblast proliferation.

Cysts located on teh dorsal-lateral finger at the distal interphalangeal joint = herniation of tendon sheaths or joint lining.
What are warts?
Epidermal neoplasms caused by viral infection.
A benign dermatosis that usually arises late in the third trimester of a first pregnancy.
Pruritic urticarial papules and plaques of pregnancy (PUPPP)
Where does PUPPP begin? When?
Abodomen, spreads to thighs buttocks and armsm periumbilical area is spared. Shortly after delivery.
What is a rare autoimmune disorder of pregnancy marked by urticarial patches and periumbilica plaques?
Herpes Gestationis (Pemphigoid gestationis)
What is the difference between PUPPP and herpes gestationitis?
PUPPP = no lesions on face, palms or soles. Herpes = lesions on palms and soles.
Can infants be born with a herpes rash?
Yes, but usually clears within a few weeks without treatment.
What is chronic, recurrent, erythematous scaling eruption localized in areas where sebaceous glands are concentrated (scalp, back, inertringinous and diaper areas)?
Seborrheic dermatitis
What factors are associated with seborrheic dermatitis?
Hormone levels, fungal infections, nutritional deficits, neurogenic factors, infants (first 3 months of life).
What is a yellow crusted rash on the scalp of an infant called?
Cradle cap
What is Miliaria Rubra?
"Prickly heat" caused by sweat retention from occlusion of sweat ducts during periods of heat and high humidity. Overstressed babies get this.
What is a common, contagious superficial skin infection caused by staph?
Impetigo
What does impetigo begin as?
Small erythematous macule that changes into a vesicle or bulla with a thin roof, have a honey color, regional lymphadenopathy.
What is caused by androgens stimulating pilosebaceous units at the time of puberty to secrete large amounts of sebum?
Acne Vulgaris
What is characterized by open blackheads and closed whiteheads "comedones", inflammatory papules, neutrophils causing an inflammatory response, and "ice pick" scarring?
Acne Vulgaris
An acute highly communicable disease common in children and young adults?
Chickenpox (Varicella)
How is chickenpox spread?
Droplet transmission, airborne. Incubation period of 2 to 3 weeks, 1-2 days contagious and then onset of rash.
What is characterized by maculopapular and vesicular lesions on trunk, extremities, face, buccal mucosa, palate or conjunctiva, accompanied by headache, sore throat, mild malaise?
Chickenpox
How does measles virus infect a person?
Through the respiratory epithelium, primary viremia where the virus spreads in leukocytes to teh reticuloendothelial system, thymus, spleen, lymphnodes, liver, skin, conjunctiva, and lung.
What is the incubation period for measles?
18 days, contagious a few days before fever and 4 days after rash.
What characterizes measles?
Prodromal fever, conjuncivitis, coryza and bronchitis, blotchy rash (Koplik spots), macular rash.
How long does a measles rash last?
4-7 days
What is the incubation period of german measles (rubella)
14-23 days. Infectious while rash is erupting, can shed virus from throat from 10-15 days after the onset of the rash.
What is characterized by a light pink to red maculopapular rash, and appears on the soft palate (Forschheimer spots)?
German measles
What is loss of scalp hair from pulling called?
Trichotillomania.
What are 4 patterns of physical abuse?
Bruises, lacerations, burns, hair loss.
Where does stasis dermatitis occur?
Lower legs = venous insufficiency.
What are the causes of stasis dermatitis?
Venous insufficiency, incompetent valves, inflammatory responses, genetic or environmental factors, allergic response to an epidermal protein antigen
What is characterized by increases in pigmentation and redness, itchyness, scaling weeping patches and ulcers on lower extremities?
Stasis dermatitis
Squamous cell carcinoma confined to the epidermis, occurs secondary to chronic sun damage.
Solar keratosis (Actinic keratosis)