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31 Cards in this Set

  • Front
  • Back
what are the 2 types of melanocytic nevi?
congenital and acquired
what are the 3 types of acquired melanocytic nevi? **
Junctional- nevus cells remain at DE junction

Compound- nevus cells found at DE junction and in the dermis

Dermal- nevus cells found in the dermis
where do you commonly find dermal nevi?
on the face :)
how do congenital nevi grow ?
they grow as the child grows
Small congenital nevi: size? malignant potential?
<1.5cm

not normally malignant
Medium congenital nevi: size? malignant potential?
1.5cm-19.9cm

Malignant potential controversial

if it is in an easily visualized place, leave it, if not easily monitored, take it out
Large congenital nevi: size? malignant potential?
5% or greater body surface; usually on trunk (>20 cm)

Malignant transformation occurs
Incidence 1.8-7.1%
Half of the melanomas occur by age 3-5


Removal if possible
are blue nevi more likely to be melanoma?
no, they are only blue because of the the Tyndall Effect
what is a dysplastic nevi?
Marker for increased risk of melanoma
NOT a true “pre-cancer”
May have “fried egg” appearance
Irregular and dark pigmentation
Irregular borders
if you have a nevi with “fried egg” appearance
Irregular and dark pigmentation
Irregular borders what type of nevi is it? what is it a marker for
dysplastic

marker for increased risk of melanoma
**** What is a Becker's Nevus?

TEST
Hamartomatous growth of smooth muscle fibers

Can consist of a brown macule, a patch of hair, or both

Can be assosiated with hypoplasia of ipsilateral limb or breast, or skeletal anomalies

Malignancy has never been reported
a patient has a Hamartomatous growth of smooth muscle fibers

what is this?

TEST*
Becker's Nevus
are there increased melanocytes in a Becker's Nevus
NO!
patient comes in with a depigmented area with a mole in the middle. What is this? what caused it
Halo Nevus

immune reaction to nevus
between the age of 25-30 what is the most commonly occurring cancer in women/
melanoma
what is the most common type of melanoma? ***TEST

occurs where?
Superficial spreading Type


back and legs
the 2nd most common melanoma is very aggressive. What is it?
nodular type
a patient comes in with what looks like a button mushroom growing on the back of the leg. After biopsy there was still pigment in the dermis. What does this patient have?
nodular type melanoma
a liver spot is what? what causes it? is it likely to kill you
lentigo maligna

sun damage

no
a man comes into the office with a melanoma on the toe and and part of the sole of their foot. What is this? What type of patient was it? is it aggressive?
Acral lentiginous type malignant melanoma

likely a black or asian person

VERY AGGRESSIVE cut that shit out
what is Hutchinson's sign?
What is it a sign of?

**TEST
Appearance of a pigmented band with extension into the proximal or lateral nail fold


Suggests acral lentiginous melanoma (ALM)
what are the ABCDE's of malignant melanoma
Asymmetry
Border (is it smooth?)
Color (more color=bad)
Diameter (larger=bad)
Evolving (any changes noted by the patient)
do all melanomas have pigment in them?
not necessarily
when you suspect a melanoma, what is the thing you MUST do?
BIOPSY
what is the recommended biopsy?
biopsy down to fascial plane (when possible)
what is the Breslow Depth?

****MUST KNOW
Measured from the granular layer to the deepest portion of malignant cells
what is the determinant of prognosis for melanoma?
The Breslow Depth
Higher Breslow Depth means?
MORE LIKELY TO BE MALIGNANT
Breslow Depth greater than 1mm means what?
higher risk for metastasis

Recommend sentinel lymph node biopsy

this shit is serious
what is a sentinel lymph node?
1st lymph node in the LN basin to which the primary drains
Lymph node most at risk for metastasis


put in dye, see where it goes to with the most dye, and cut that bad boy out

this is a diagnostic test for malignant melanoma
if you have a >1mm Breslow thickness what are you going to do?

**TEST
sentinel lymph node biopsy