Skin

Front 1

what langerhan cells display

Back 1

MHC Class I & II, CD40, CAMs, B7

Front 2

Dendritic shaped cells

Back 2

langerhan cells

Front 3

langerhan cells are...

Back 3

APC's

Front 4

major cell type of the epidermis

Back 4

keratinocytes

Front 5

keratinocytes present/produce?

Back 5

MHC Class I & II, cytokines, and prostaglandins

Front 6

what type of hypersensitivity is allergic contact dermatitis

Back 6

Type 4

Front 7

is an inflammatory skin disease caused by cell-mediated hypersensitivity to external agents that contact the skin

Back 7

Contact dermatitis
(Sensitization may take days or years)

Front 8

Blisters > AB > immunofluorescence

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Immunobollous disease

Front 9

Bullous Pemphigoid

Back 9

subepidermal: IgG and complement

Front 10

Pemphigus

Back 10

intraepidermal: most serious immunobollous disease

Front 11

Dermatitis herpetiformis

Back 11

subepidermal: IgA, complement, and enteropathy

Front 12

Strong association with HLA-DRB1*0402

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Pemphigus

Front 13

Widespread blistering of skin and mucous membranes

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Pemphigus

Front 14

Intensely pruritic vesicles

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Dermatitis Herpetiformis

Front 15

Dermatitis Herpetiformis is associated with...

Back 15

gluten-sensitive enteropathy

Front 16

Chronic relapsing skin disease

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Psoriasis

Front 17

Typical features of psoriasis lesions...

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Sharply demarcated with clear-cut borders;
Noncoherent silvery scales;
Glossy homogeneous erythema;
Positive Auspitz sign

Front 18

The skin changes in psoriasis stem from

Back 18

increased rate of proliferation and shedding of keratinocytes.

Front 19

Keratinocytes gone Baaaaadddd?
T-cell mediated process
Role of cytokines

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Pathogenesis of Psoriasis

Front 20

Superficial Fungal Diseases

Back 20

Pityriasis versicolor;
Tinea nigra;
Black/White piedra

Front 21

Cutaneous fungal diseases

Back 21

tineas (dermatophytoses)

Front 22

Subcutaneous fungal diseases

Back 22

Chromoblastomycosis;
Sporotrichosis;
Mycetoma

Front 23

chronic, mild infection of stratum corneum, results in scaly lesions.

Back 23

Pityriasis (or tinea) versicolor

Front 24

Is there an inflammatory response in pityriasis versicolor?

Back 24

hell nah

Front 25

pityriasis versicolor is caused by?

Back 25

Malassezia furfur

Front 26

treatment of Malassezia overgrowth

Back 26

Itraconazole/ketoconazole;
Selenium Sulfide;
Pyrithione zinc

Front 27

brown/black macular lesions usually on hands and/or feet. May resemble melanoma

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tinea nigra

Front 28

is tinea nigra non scaling?

Back 28

yep

Front 29

(T-F) tinea nigra is non inflammatory

Back 29

TRUE

Front 30

brown-black pigmented yeasts, found in soil, shower curtains

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Exophiala werneckii

Front 31

Phaeohyphomycoses

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diseases caused by unrelated dark pigmented fungi

Front 32

infection on external hair shaft, forming either black nodules or white nodules

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Black piedra, White piedra

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black piedra

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Piedraia hortae

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white piedra

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Trichosporon beigelli

Front 35

classified based on location of infection. Will induce an inflammatory response. Metabolize keratin

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dermatophytoses,(ringworms)

Front 36

ringworm of trunk, legs

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tinea corporis

Front 37

concentric rings of scales over trunk, legs, forearms

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tinea imbricata

Front 38

scaling between the toes, lateral side of the foot. “Moccasin pattern”. Itching, skin cracks.

Back 38

tinea pedis (athlete's foot)

Front 39

rash, scaling, inner thighs

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tinea cruris (jock itch)

Front 40

disease of children, classified as ectothrix or endothrix

Back 40

tinea capitis (scalp ringworm, favus)

Front 41

ectothrix

Back 41

conidia outside of hair shaft

Front 42

endothrix

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conidia inside of shaft

Front 43

hair loss, scaling, and inflammation of the scalp skin,
itching; can be confused with dandruff, seborrheic dermatitis

Back 43

tinea capitis (scalp ringworm, favus)

Front 44

infection of the hair and skin around the bearded areas of the neck and face

Back 44

tinea barbae

Front 45

fungal infection of the nails, causing thickening, fissuring, colorization (brown, white, yellow).

Back 45

tinea unguium (onychomycosis)

Front 46

wart-like, cauliflower, pigmented lesions, usually of the foot.

Back 46

chromoblastomycosis

Front 47

chromoblastomycosis

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Fonsecaea pedrosoi, Cladosporium carrionii, Phialophora verrucosa

Front 48

- ulcerative papule, spreads via draining lymph channels, nodular granulomas, chronic

Back 48

sporotrichosis (rose thorn disease)

Front 49

sporotrichosis (rose thorn disease)

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Sporothrix schenckii

Front 50

infection via thorns and
splinters. Small, painless papules and nodules, sinus
tract formation leads to spread, deeper tissue infiltration. Can lead to bone destruction over a period of months/years

Back 50

mycetoma (Madura foot)

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mycetoma (Madura foot)

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Pseudoallescheria boydii, Madurella mycetomatis

Front 52

tineas (dermatophytoses)

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Trichophyton, Epidermophyton and Microsporum sp. Candida sp.

Front 53

Chromoblastomycosis

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Fonsecaea, Cladosporium, Phialophora sp

Front 54

Mycetoma

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Pseudoallescheria, Madurella sp.

Front 55

a distinct acute variant of psoriasis noted for fever which may last several days, sudden generalized eruption of sterile pustules 2-3 mm in diameter, usually over the trunk; also weight loss, muscle weakness, leukocytosis, and congestive heart failure.

Back 55

Generalized pustular Psoriasis

Front 56

a generalized form of the disease which affects all body sites; erythema is the most prominent feature with less scaling.

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Psoriatic erythroderma

Front 57

small lesions over the upper trunk and proximal extremities; characteristic of psoriasis at an early age; may be preceded by streptococcal throat infection.

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Eruptive (Guttate) Psoriasis

Front 58

the most frequent clinical pattern, characterized by red scaly lesions that persist for months to years, usually on the elbows, knees, the scalp, behind the ears, and around the navel.

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Plaque Psoriasis