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9 Cards in this Set
- Front
- Back
Aminoglycosides |
Sai Dead Kanji translator under 30S clock = bind onto bacterial ribosome subunit 30 making it bacteriocidal Smeared Kanji = misreading of mRNA Beta-lactam bomb = coupled with cell wall active drugs (beta-lactams, vancomycin) Bellows = transported into bacteria via oxygen dependant process (aerobic bacteria) Innctivating ninja stars = Innactivated by acetylation enzyme(faecium) |
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Aminoglycoside Targets |
Red bacilli bricks = activity against aerobic gram negative bacilli Double purple taiko drums = activity against enterococcus when coupled with cell wall active agent (vancomycin, penicillin) |
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Neomycin |
Ninjitsue master Secret colon tunnel = neomycin remains active in GI tract Scalpel shuriken = neomycin used in bowel prep before colorectal surgery |
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Paromycin |
Pair of mice Luminal agent against parasites |
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Streptomycin |
Sai master Rabbit ears = treats tularemia caused by Francisella tularenis Squirrels with fleas = treats plague caused by Yersinia pestis |
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Gentamicin |
Judo master = treats resistant gram negative infections (enterobactor, seratia, klebesella) Red Shogun = systemic gram negative infections (septicemia, nosocomial RTI, UIT, intra-abdominal infection) Mona Lisa = activity against Pseudomonas |
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Tobramycin |
Cobra ninja Similar spectrum to gentamicin) |
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Amikacin |
Katana Master Mona Lisa = activity against Pseudomonas |
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Amikacin Side effects |
Cracked gong = ototoxicity (vestibular or cochlear damage) Sai in kidney shaped flank armor = nephrotoxicity Rusty downspout draining muddy water = acute tubular necrosis (ATN) Peak and troughs = monitoring of serum drug levels Sai in electrical outlet = myesthenia gravis is an absolute contraindication to amino glycoside use Tarantula on gong = teratogenic - deafness in newborn |