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9 Cards in this Set

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  • Back

Aminoglycosides

Sai


Dead Kanji translator under 30S clock = bind onto bacterial ribosome subunit 30 making it bacteriocidal


Smeared Kanji = misreading of mRNA


Beta-lactam bomb = coupled with cell wall active drugs (beta-lactams, vancomycin)


Bellows = transported into bacteria via oxygen dependant process (aerobic bacteria)


Innctivating ninja stars = Innactivated by acetylation enzyme(faecium)

Aminoglycoside Targets

Red bacilli bricks = activity against aerobic gram negative bacilli




Double purple taiko drums = activity against enterococcus when coupled with cell wall active agent (vancomycin, penicillin)

Neomycin

Ninjitsue master


Secret colon tunnel = neomycin remains active in GI tract


Scalpel shuriken = neomycin used in bowel prep before colorectal surgery

Paromycin

Pair of mice


Luminal agent against parasites

Streptomycin

Sai master


Rabbit ears = treats tularemia caused by Francisella tularenis


Squirrels with fleas = treats plague caused by Yersinia pestis

Gentamicin

Judo master = treats resistant gram negative infections (enterobactor, seratia, klebesella)


Red Shogun = systemic gram negative infections (septicemia, nosocomial RTI, UIT, intra-abdominal infection)


Mona Lisa = activity against Pseudomonas

Tobramycin

Cobra ninja


Similar spectrum to gentamicin)

Amikacin

Katana Master


Mona Lisa = activity against Pseudomonas

Amikacin Side effects

Cracked gong = ototoxicity (vestibular or cochlear damage)


Sai in kidney shaped flank armor = nephrotoxicity


Rusty downspout draining muddy water = acute tubular necrosis (ATN)


Peak and troughs = monitoring of serum drug levels


Sai in electrical outlet = myesthenia gravis is an absolute contraindication to amino glycoside use


Tarantula on gong = teratogenic - deafness in newborn