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47 Cards in this Set

  • Front
  • Back

Type 1 Size

Small

Type 1 Energy Supply

Oxidative phosphorylation (aerobic)

Type 1 Mitochondria

Greater and larger

Type 1 Color

Red

Type 1 SR

Less

Type 1 Contraction and Conduction

Slow

Type 1 Fatigue

High Resistance

Soleus muscle

Type 1

Maintaining posture

Type 1

Type 1 Nerve supply

Innervated by small nerve fibers

Myoglobin

Red pigment - oxygen binding (in type 1)

Type II A Energy Supply

Fast Oxidative

Type II B Energy Supply

Fast Glycolytic

Gastrocnemius muscle

Combo of Type 1 and Type II A

Fatigue

Glycogen is consumed


Accumulation of extracellular K+


lactic acid accumulation


nerve fibers use up Ach

Passive tension

Tension when stretching a muscle

Total tension

Tension when muscle is contracted to different loads

Active tension

Total tension - Passive tension

Isometric contraction

Static work - no change in length but tension increases

Isotonic contraction

Change in length but constant tension

Creatine Phosphate

ADP -> ATP


Enzyme: Creatine Phosphokinase


ADP + Creatine Phosphate -> ATP + Creatine

Glycolysis

Breakdown of glycogen -> pyruvic & lactic acid


Glycolysis: ADP -> ADP


Cytosol


2.5 times faster than aerobic


can occur without oxygen

Fenn effect

Greater amount of work performed = greater amount of ATP cleaved


Phosphagen System

4 moles/min


8-10 seconds

Glycogen lactic acid system

2.5 moles/min


1.3 - 1.6 min

Oxidative system

1 mole/min


unlimited

Activation Heat

Release of heat during twitch/tetanus


1. release of Ca from SR


2. binding of Ca to Troponin C

Shortening Heat

Heat due to crossbridge cycling and breakdown of glycogen

Maintenance Heat

Calcium accumulation

Recovert Heat

Heat released when resynthesizing substances after they were broken down

Labile meaintenance heat

binding Ca to sarcoplasmic proteins

Stable maintenance heat

Crossbridge turnover and reuptake of calcium

Heat of Relaxation

Heat produced when muscle lengthens during relaxation

Shape and nuclei of skeletal muscle

Cylindrical, multinucleated

Shape and nuclei of smooth muscle

Spindle, mononucleated

Shape and nuclei of cardiac muscle

Cylindrical and branched, mononucleated and binucleated

Intercalated disks

In Cardiac muscle

Unitary smooth muscle

Connectional units

Multiunit smooth muscle

No connectional units

Malignant Hyperthermia

Defect in SR


Ca release channels (RYR) becomes activated


Muscle rigidity, tachycardia, hyperthermia, and hyperventilation

Central Core Disease

Defect in RYR


Increases intracellular Ca which leads to overload of Ca and loss of mitochondria


muscle weakness

Brody Disease

Decreased activity in Sarcoplasmic/Endoplasmic reticulum


Results in Muscle camping

Rigor Mortis

Absence of ATP which is required to release myosin head from actin

Effect of Denervation

muscle atrophy


fibrillation - jerky stimulation

Fasciculation

jerky contractions that ocur due to discharge of spinal motor neuron

Myasthenia Gravis

muscle weakness due to destruction of acetylcholine receptors at NMJ

Summation

Adding individual twitch contractions to increase overall muscle contraction