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30 Cards in this Set
- Front
- Back
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choline + acetate ----> acetylcholine
----> = ? |
choline acetylase (CoA)
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gas retention
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anti-flatulant
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stimulate GI tract without significant impact on secretions
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prokinetic agent
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CNS + peripheral
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antidopamine effect
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GERD
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gastroesphogeal reflux disease (heart burn)
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used in combination to decrease nausea and vomitting associated with cancer chemotherapy
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antiemetic
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abnormal muscle twitching (cause by metaclopramide)
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dyskineasias
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are lipid soluble and distribute into CNS which is not a desirable effect
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secondary and tertiary amines
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constriction of the pupil
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miotic
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agents inhibit cholinesterase which increases concentration of ACh
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indirect acting cholinergic agents
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generally carbamic acid esters
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reversible ChE Inhibitors
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increase IOP leads to degernation of the optic nerve and retina
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glaucoma
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obstructed drainage of aqueous humor
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angle closure or narrow angle glaucoma
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drainage problem usually due to increae resistance in the canal of schlemm or tobecular meshwork
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wide angle or open angle glaucoma
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some identifiable cause such as tumors or trauma to the eye, not really common
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secondary glaucoma
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infantile glaucoma, may affect canal of schlemm, may or may not be correctable, extremely rare
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congenital glaucoma
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decrease IOP by increasing drainage of aqueous humor, used in combo with miotic agent
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sympathomimetic agents
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decrease formation of aqueous humor, may increase drainage a small amount
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alpha 2 adrenergic receptor agonist
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reduce IOP formation by reducing availability of HCO3-
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carbonic anhydrase inhibitors
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decrease IOP by increasing drainage of aqueous humor
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prostaglandin analogs
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underdosing
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myasthenic crisis
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overdosing
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cholinergic crisis
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removes source of antibodies in combination with plasmapheresis
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thymectomy
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decline in memory and cognitive function
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dementia
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filaments present in cytoplasmic space
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tangles
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clusters of degernating neurons associated with amyloid protein
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neuritic plaques
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more direct effect will effect not only early on but longer into the disease
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M1 receptor agonists
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pupil dialation
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mydriasis
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paralysis of accomodation
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cycloplegia
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use to suppress HCl acid secretion to allow ulcers to heal
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H2 receptor inhibitors
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