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30 Cards in this Set

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choline + acetate ----> acetylcholine

----> = ?
choline acetylase (CoA)
gas retention
anti-flatulant
stimulate GI tract without significant impact on secretions
prokinetic agent
CNS + peripheral
antidopamine effect
GERD
gastroesphogeal reflux disease (heart burn)
used in combination to decrease nausea and vomitting associated with cancer chemotherapy
antiemetic
abnormal muscle twitching (cause by metaclopramide)
dyskineasias
are lipid soluble and distribute into CNS which is not a desirable effect
secondary and tertiary amines
constriction of the pupil
miotic
agents inhibit cholinesterase which increases concentration of ACh
indirect acting cholinergic agents
generally carbamic acid esters
reversible ChE Inhibitors
increase IOP leads to degernation of the optic nerve and retina
glaucoma
obstructed drainage of aqueous humor
angle closure or narrow angle glaucoma
drainage problem usually due to increae resistance in the canal of schlemm or tobecular meshwork
wide angle or open angle glaucoma
some identifiable cause such as tumors or trauma to the eye, not really common
secondary glaucoma
infantile glaucoma, may affect canal of schlemm, may or may not be correctable, extremely rare
congenital glaucoma
decrease IOP by increasing drainage of aqueous humor, used in combo with miotic agent
sympathomimetic agents
decrease formation of aqueous humor, may increase drainage a small amount
alpha 2 adrenergic receptor agonist
reduce IOP formation by reducing availability of HCO3-
carbonic anhydrase inhibitors
decrease IOP by increasing drainage of aqueous humor
prostaglandin analogs
underdosing
myasthenic crisis
overdosing
cholinergic crisis
removes source of antibodies in combination with plasmapheresis
thymectomy
decline in memory and cognitive function
dementia
filaments present in cytoplasmic space
tangles
clusters of degernating neurons associated with amyloid protein
neuritic plaques
more direct effect will effect not only early on but longer into the disease
M1 receptor agonists
pupil dialation
mydriasis
paralysis of accomodation
cycloplegia
use to suppress HCl acid secretion to allow ulcers to heal
H2 receptor inhibitors