Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
9 Cards in this Set
- Front
- Back
|
Lab test results for Shigella
|
G- rod
Gas - H2S - NM Lac - TSI alk/acid citrate - lys - |
|
|
what disease is caused by Shigella, and what are the symptoms?
|
Bacillary Dysentery
cramping, abdominal pain, diarrhea w/ blood and mucous bacteria invade mucosal cells of distal ileum and colon, inflammation and ulceration occurs, but bact rarely penetrate wall or bloodstream 200> cause disease |
|
|
What are the virulence factors of Shigella?
|
Heat labile exotoxin (shiga neurotoxin) *S. dysenteriae*
B subunit binds, A subunit inhibits protein synthesis and alters the epithelial cells' ability to transport electrolytes, leading to fluid accumulation in intestine. also neurotoxin can result in convulsions/coma extrachomosomal "invasins" mediate intracellular spread of organism |
|
|
What is shigellosis?
|
disease with asymptomatic carriers, resides in the gall bladder and GI tract.
symptoms: fever, cramps, watery->mucous->bloody diarrhea spread by the 5 F's: fingers, flies, fomites, food, feces S. dysenteriae is severe, S. sonnei is mild Treat with fluids and ampicillin |
|
|
How do you differentiate S. dystenteriae?
|
mannitol -
|
|
|
How do you differentiate S. flexneri?
|
Raffinose delayed
|
|
|
How do you differentiate S. boydii?
|
mannitol +
orn - raffinose - |
|
|
How do you differentiate S. sonnei?
|
orn +
ONPG + |
|
|
Describe Edwardsielleae
|
found in nature, fish
Edwardsiella tarda H2S + causes gastroenteritis and wound infections |
