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52 Cards in this Set
- Front
- Back
List the three components of a reflex.
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Afferent signal (input), processor/controller, efferent signal (ouput), effector organ
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What generates the afferent signal for a cardiovascular reflex?
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Mechanoreceptors (stretch receptors)
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What serves as the processor/controller for a cardiovascular reflex?
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Brainstem is the primary integrator
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What are the 3 effector systems which are the pathways for efferent signal?
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Sympathetic NS, Parasympathetic NS, and endocrine system
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What is the name given to mechanoreceptors in the walls of the arteries?
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baroreceptors
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What is the name given to mechanoreceptors in the walls of the heart chambers?
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cardiopulmonary receptors
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What are the 2 effector targets?
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Heart and blood vessels
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How does the kideny participate in long term regulation of the CV system?
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Adjusts blood volume
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What receptor types, which effect the CV system are sensitive to blood chemistry?
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Chemoreceptors
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Where is the highest concentration of the most sensitive baroreceptor found?
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In the carotid sinus at the bifurcation of the internal and external carotid arteries
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Besides the carotid sinus list two other locations where baroreceptors can be found.
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Other parts of the carotid artery and around the aortic arch
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Define: the pressure differential across the wall of the vessel.
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transmural pressure
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What is the critical parameter measured by baroreceptors?
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transmural pressure
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An increase in mean arterial blood pressure will result in an ____ in the rate of nerve impulse generation of the baroreceptor (sinus nerve).
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Increase
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True/False, systolic and diastolic pressure difference produce the same sinus nerve response.
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False, impulse generation is greater during rises in pressure (systole) than during decreases (diastole)
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If the wall is stiffened by contraction of smooth muscle, what is the effect on the sensitivity of the baroreceptors?
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Sensitivity will decrease because the transmural pressure will not change.
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Mechanoreceptors are a type of _________ receptor.
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Stretch
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When the wall of the carotid artery expands (or contracts) how does the baroreceptor respond?
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Increases impulse generation
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Locate the primary locus for integration of the cardiovascular reflex system in the brain.
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Upper medulla
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List the four major areas for cardiovascular control in the brain.
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Upper medulla, hypothalamus (temperature reg, volume etc), cortical areas (i.e. blushing), and spinal cord (primitive reflexes)
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True/False, in the upper medulla when the more laterally located sympathetic nervous system is activated, the more medially located parasympathetic (vagal) nervous system is simultaneously inhibited.
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TRUE
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What nervous system is the dominant effector in baroreflex responses?
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Sympathetic NS
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Sympathetic nervous activity is directly __________ to the amount of baroreceptor input to the brain.
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opposite
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What nervous system is activated by rising blood pressure and results in decreased heart rate and reduces the contractile state of the heart?
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Parasympathetic NS
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What are the two fold effects of the sympathetic NS on the venous system?
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1. decreasing of reservoir space (venous volume) 2. Increase venous return to the heart (by increasing mean systemic filling pressure and/or decreasing the resistance to venous return.)
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An increase in sympathetic activity will cause an _________ in vascular resistance.
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Increase
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A decrease in sympathetic activity will cause a ___________ in vascular resistance.
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Decrease
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An increase in sympathetic activity creates a ___________ heart.
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hypereffective
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Heart rate is __________ with increased sympathetic activity.
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increased
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What two effects does sympathetic activity have on the heart?
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Increases heart rate and makes the heart hypereffective
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Will the parasympathetic Nervous system cause a small or great depression in contractile state?
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Small depression
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An increase in parasympathetic activity will cause a ___________ in heart rate.
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decrease
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What is the primary endocrine organ involved in the baroreceptor reflex?
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Adrenal gland
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What are the two hormones released by the adrenal medulla which both effect blood pressure?
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Norepinephrine and epinephrine
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What two effects does epinephrine have on the myocardium?
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increases heart rate and contractile state
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What neurotransmitter is shared by the adrenal medulla and the sympathetic nervous system?
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norepinephrine
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What does Renin (produced by the kidneys) stimulate?
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The formation of angiotensin
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What is the effect of angiotensin on the blood vessels?
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Very strong angiotensin
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What two conditions need to be met for the kidney to release renin?
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Low blood pressure and/or sympathetic activity is elevated
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Vasopressin is a vasoconstrictor or a vasodilator?
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Vasoconstrictor
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What brain structure releases vasopressin?
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hypothalamus
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What is the short term and long term purported function of the atrial mechanoreceptor reflex?
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short-term vasoconstriction (through release of vasopressin, aka ADH) and long-term response for fluid conservation.
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Describe the components of the atrial mechanoreceptor reflex.
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Stretch receptors located in the walls of both the left and the rigth atria, consisting of a type A and Type B. Send information to brain and modulate the release of vasopressin.
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When are Type A atrial mechanoreceptor reflex receptors active?
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During atrial contraction (called such because they are associated with the "a" wave of atrial pressure)
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When are Type B atrial mehcanoreceptor reflex receptors active?
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During atrial filling (called such because they are associated with the "v" wave in atrial pressure)
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Besides the baroreceptor reflex and the atrial mechanoreceptor reflex, list two other cardiovascular reflexes.
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CNS Ishemic reflex and Diving reflex
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What elicits the CNS Ishemic reflex?
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When the blood pressure falls below 40 mmHg (inadequate for brain perfusion)
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What is the dominant reflex effect of the CNS ischemic reflex?
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sympathetic vasconstriction (additionally, an increase in heart rate)
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If CSF pressure approaches within 30-40 mmHg what occurs?
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CNS Ishemic reflex (as well as cushing response and sometimes accompanies by a vagally induced bradycardia)
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Describe the Cushing response/reflex.
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When CSF pressure > Mean Arterial Pressure, sympathetic nervous system activated resulting in a sudden change in blood pressure causing the baroreceptors to induce bradycardia (Cushing's triad)
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Describe the diving reflex.
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Elicited by exposing the nasopharynx to wet cold stimuli, trigeminal nerve carries signal and induces bradycardia and vasoconstriction (especially in the abdominal organs).
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What is the use of the diving reflex?
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Conserves energy while diving, increasing submersion time/depth, may be used clinically to retard tachycardia
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