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18 Cards in this Set
- Front
- Back
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Neisseria Gonorrhea bacteria
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Gram negative diplococci
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Gonorrhea Pathogenesis
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1. Bacteria attaches to cervix or urethra mucosal epithelial cells
2. Phagocytosis of bacteria, mucosal cells damaged 3. Leads to inflammation and recruitement of WBC 4. Abscesses can form and purulent exudates are secreted |
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Chlamydia Trachomatis Bacteria
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Intracellular gram negative bacterium; contain inclusion bodies in which bacteria replicates
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Chlamydia Pathogenesis
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1. Bacteria enters cervix or urethral epithelial cells
2. Replication of bateria occurs in vesicles 3. Infectious particles are released from epithelial cells and move onto new cells 4. Symptoms can result from inflammation |
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Treponema Pallidum (Syphillis)
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Spirochete
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Syphillis Pathogenesis (Primary)
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1. Bacteria comes into contact with cutaneous surfaces/mucous membranes
2. Single, painless, indurated lesion appears (chancre), heals in 1-8 weeks w/o drugs |
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Syphillis Pathogenesis (Secondary)
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1. Bacteria spreads through body
2. Generalized skin lesions, often on palms and soles 3. Systemic symptoms can occur- fever, malaise, headache, arthralgias (joint pain) 4. lesions will resolve in 4-10 weeks |
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Syphillis Pathogenesis (Tertiary)
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1. Bacteria can infect organs of body
(neurosyphillis- infects CNS) |
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Herpes Simplex Virus 1&2 Pathogenesis
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1. Infected secretion come into contact with mucosal surface
2. virus invades and undergoes replication 3. spreads to peripheral sensory nerve cells 4. Latency- virus stored in nerve cells dormant; stress, trauma, immunocompromise may activate it |
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Difference between HSV 1 and HSV 2?
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HSV 1: oral herpes; causes genital lesions through sexual activity
HSV 2: genital herpes; cause oral lesions through sexual activity |
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HSV 1: Primary Infection
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1+ fluid filled lesions present
Pharyngitis Fever/Swollen Lymph nodes Mouth pain/Blisters - resolve in 2-8 days |
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HSV 1: Recurrence/Reactivation
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Burning and itching (prodrome) 24hrs before lesions reoccur
Lip lesions are common Mouth pain and blisters resolve in 8 days |
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HSV 2: Primary Infection
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Commonly asymptomatic
Multiple, pus filled painful lesions 7-10 days onset 2-4 weeks healing time Flulike symptoms |
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HSV 2: Recurrence
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Prodrome 24 hours prior to lesion reoccurence
Less severe, fewer lesions 7-10 day onset 7 day healing |
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Diagnosis of Chlamydia/Gonorrhea
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Rapid Antigen Testing
Gram stain/culture of specimen |
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Diagnosis of HSV 1/2
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Tissue culture
HSV DNA detection through PCR |
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Diagnosis of Syphillis
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Microscopic examination of lesion material
Serologic studies |
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Complications of Chylamidia/Gonorrhea
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Female infertility
Neonatal Infection (also through HSV/Syphillis) |
