Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
40 Cards in this Set
- Front
- Back
|
Herpes on a Tzanck test. See multi-nucleated giant cell. Not characateristic of a specific herpes virus.
|
What is this cytology?
|
|
|
What are the characteristics of an acute primary HSV infection?
|
Painful bilateral genital ulcers, dysuria, systemic symptoms (fever), local PAIN, headache
|
|
|
What are the characteristic ulcers in syphilis?
|
Painless, shallow ulceration
|
|
|
What are the characteristics of secondary syphilis?
|
Salmon-colored rash involving palms and soles.
|
|
|
Secondary syphilis (this is condyloma lata)
(condyloma accuminata are the warts of HPV) |
What is this lesion a sign of?
|
|
|
What are manifestations of tertiary syphilis?
|
Gummas
Acute syphilitic meningitis Meningovascular syphilis General paresis Tabes dorsalis Aortic aneurysm Hutchinson's teeth |
|
|
What is the treatment for syphilis?
|
Benzathine penicillin (long-acting injection in buttock)
No resistance yet. If allergic --> doxycycline |
|
|
What organism causes Chancroid?
|
Hemophilus decruyi
|
|
|
Hemophilus ducreyi, the cause of chancroid.
See "school of fish" appearance |
What organism is this?
|
|
|
What is the lesion progression in chancroid?
|
Erythematous papule --> pustule --> ulcer
Confined to genital area and draining LN Ulcer is 102 cm, painful, typically single in men, multiple in women Inguinal lymphadenitis is common in men, not in women. Nodes may liquefy and turn into buboes |
|
|
What is the treatment of chancroid?
|
Azithromycin, ceftriaxone, ciprofloxacin, erythromycin
Aspirate buboes, treat partners |
|
|
What is the clinical course of lymphogranuloma venereum?
|
Primary - Vesicle, papule or ulcer not bothersome
Secondary - regional lymphadenopathy, fever, headache, myalgias "groove sign" in men, inguinal region Tertiary - suppurative adenitis, bubo, fibrosis |
|
|
How does LGV cause lymphadenopathy?
|
Direct extension from primary site to LN, binds epithelial cells, causes necrosis within nodes, followed by abscess formation
Results in inflammation and fibrosis |
|
|
How is LGV treated?
|
Doxycycline or erythromycin, or Azithromycin
Aspiration of buboes |
|
|
Syphilis
Incubation Early lesion # lesions Depth Adenopathy Pain |
9-90 days
Papule One Deep or superficial Firm, nontender, bilateral Uncommon |
|
|
Herpes
Incubation Early lesion # lesions Depth Adenopathy Pain |
2-7 days
Vesicle Multiple Superficial Firm, tender Tender |
|
|
Chancroid
Incubation Early lesion # lesions Depth Adenopathy Pain |
1-14 days
Pustule Multiple Excavated Tender, may suppurate Very tender |
|
|
LGV
Incubation Early lesion # lesions Depth Adenopathy Pain |
3-6 weeks
Papule, pustule, or vesicle One Superficial or deep Tender, may suppurate Tender |
|
|
What are the two main causes of urethral discharge?
|
Chlamydia trachomatis
Neisseria gonorrhoeae |
|
|
What is the microscopic appearance of Neisseria gonorrhoeae?
|
non-motile gram-negative diplococcus
|
|
|
What are the available tests for N. gonorrhea, and what are their sensitivities?
|
Gram stain (95% in symptomatic, 50-70% in asymptomatic)
DNA probe - 89-95% LCR/PCR - 90-98% |
|
|
What are the manifestations of gonorrhea in females?
|
Cervicitis (vaginal discharge, friable mucosa, pain is atypical)
Anorectal itching, discharge Pharyngitis PID Perihepatitis Disseminated GC infxn - arthritis |
|
|
What drugs are used to treat GC?
|
Third generation cephalosporins, quinolones
Treat presumptively for chlamydia, too. Resistance to fluoroquinolones in HI and CA |
|
|
What STD may cause joint swelling and pain?
|
Gonorrhea
|
|
|
What is the most common cause of the increasing number of tubal pregnancies and infertility problems in women in the US?
|
Asymptomative chlamydia infection
|
|
|
What are the clinical features of chlamydia in women?
|
Cervicitis with vaginal discharge and abdominal pain, may be friable or edematous
Dysuria-pyuria syndrome Perihepatitis (Fitzhugh-Curtis) PID |
|
|
What is Reiter's syndrome?
|
inflammatory syndrome (etiology unknown) predominantly in males; characterized by arthritis and conjunctivitis and urethritis
|
|
|
Can you see chlamydia in gram stain?
|
No - all you can see are inflammatory cells
|
|
|
Which types of HPV cause visual genital warts?
|
6 and 11
|
|
|
Which types of HPV are associated with cervical dysplasia?
|
16, 18, 31, 33, 35
|
|
|
What lesions are associated with HPV?
|
Cutaneous warts
Condyloma acuminatum (anogenital warts) - well-circumscribed, expophytic papules Anogenital malignancies |
|
|
What is bacterial vaginosis?
|
decrease in concentration of H2O2 producing lactobacilli and increase in Gardnerella vaginalis and other species (unknown etiology)
|
|
|
Clue cell - mottled because G. vaginalis is sticking to it. No WBCs.
|
What does this cytology indicate?
|
|
|
What is the discharge like in bacterial vaginosis?
|
Thin, homogeneous, milky white or gray, adherent, often increased. "Fishy" odor (amines). Less acidic than normal.
|
|
|
What is the discharge like in Trichomonas Vaginitis?
|
Yellow-green, frothy, adherent, increased. Fishy odor may be present. Itching, dysuria.
|
|
|
What is the discharge like in Candida vulvovaginitis?
|
White, cottage cheese-like, sometimes increased. No odor.
|
|
|
What is the treatment for bacterial vaginosis?
|
Metronidazole po 7 days, or cream
Topical intravaginal clindamycin cream |
|
|
What are the findings in trichomonas vaginalis?
|
vulvar erythema, frothy yellow discharge, vaginal wall inflammation, strawberry cervix
|
|
|
Trichomonas vaginalis
|
What is this?
|
|
|
What are the vaginal pHs associated with:
Normal Bacterial Vaginosis Trichomonas vaginitis Candida Vulvovaginitis |
3.8-4.2
>4.5 >4.5 <= 4.5 |
