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9 Cards in this Set
- Front
- Back
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Intensity of disease produced
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Virulence
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# of organisms required to cause clinical disease
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Infective dose
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Microorganism becomes more virulent with each transfer through same/host species
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Animal passage
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How does Infective Dose relate to Virulence?
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The number of organisms required to cause disease illustrates an inverse relationship because the Higher # of organisms (ID)=lower virulenceAnd the Lower ID=higher virulence
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To change, to weaken diseases ability to produce pathogen
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Attenuation
*Transposal of virulenceLed to vaccines* |
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Chemically altered but still effective becomes toxoid
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Attenuated Toxin
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Reflects age, nutrition, environment
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Resident flora
*Always present* |
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Opportunists that usually cause no disease
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Normal flora
*If conditions change such as immune compromised, chemo, radiation, advance age or youth, malnutrition or other disease* |
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Presence of microorganisms, multiplication but no invasion
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Colonization
*Normal flora, Transient flora* |
