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14 Cards in this Set
- Front
- Back
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Sources of Riboflavin B2
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Milk and milk products, Green veg, eggs, meat, very sml amounts of legumes and grains
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What are the forms of Riboflavin B1
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Free Riboflavin and Protein-bound (milk and eggs)
OR Coenzyme derivatives FMN (Flavin mononucteotide), FAD (Flavin adenine do nucleotide) OR Phosphorus bound riboflavin and amino acid bound FAD |
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What happens when FAD binds to cysteine or histidine
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It is not broken down or utilised by the body and therefore excreted unchanged
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What are the enzymes needed for the absorption of Riboflavin B2
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FAD (pyrophosphatase)
FMN (phosphatase) |
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FAD is the predominant what in the tissue
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Flavoenzyme
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Free riboflavin traverses most cell membranes by a carrier-mediated process requiring a riboflavin binding protein except where
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The brain, where only FAD is transported via high-affinity
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What hormones increase conversion of Riboflavin B2 to its flaveoenzymes
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ACTH, Aldosterone and thyroid hormone
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What can be the result of sever Riboflavin B2 deficiency
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It can interfere with coenzyme reactions involving energy production, Vit B6 metabolism, synthesis of Niacin from Tryptophan
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Where are the highest concentration stores of Riboflavin B2
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Liver, Kidney and Heart
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What are agonists of Riboflavin B2
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Bile
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What are antagonist of Riboflavin B2
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Alcohol
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How is Riboflavin transported through the Brush Border
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Active transport (RFT2) and Passive Diffusion (high concentration)
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How is Riboflavin B2 transported across the Basolateral Border
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Active Transport
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Riboflavin B2 can be transported by what through
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Plasma and Albumin
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