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9 Cards in this Set

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  • Back
Serum creatinine: what does it measure
this test measures the amount of creatinine in the blood.
What is creatinine
a catabolic product of creatine phosphate, which is used in skeletal muscle contraction
what does the daily production of creatinine depend on
muscle mass, which flucuates very little.
how is creatinine excreted?
entirely by the kidneys and is therefore directly proportional to renal excretory function
what causes a rise in creatinine
beside dehydration, only such renal disorders as glomerulonephritis, pylenephritis, acute tubular necrosis, and urinary obstruction will cause abnormal elevations in creatinine.
What is the difference between BUN and Creatinine
Unlike BUN, the creatinine level is affected very little by hepatic function.
Which rises first....BUN or creatinine
BUN rises first then creatinine rises.

Therefore, elevations in creatinine suggest chronicity of the disease process.
What are renal function studies
The creatinine level is interpreted in conjuction with the BUN test.

these tests are referred to as renal function studies.

The BUN/Creatinine ration is a good measurement of kidney and liver function
What can cause decreased levels (creatinine)
debilitation
Decreased muscle mass (e.g. muscular dystrophy, myasthenia gravis)