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2 Cards in this Set
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Biological effects of TNF and Il-1 in sepsis include
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Fever
Hypotension Acute phase protein response Induction of IL-6 and IL-8 Coagulation activation Fibrinolytic activation Leukocytosis Neutrophil degranulation and augmented antigen expression (TNF) Increased endothelial permeability (TNF) Stress hormone response Enhanced gluconeogenesis (TNF) Enhanced lipolysis (TNF) |
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Direct effects of invading microorganisms or their toxic products thatcontribute to the pathogenesis of sepsis include?
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Among the potentially offending factors are endotoxin, cell wall components of bacteria (peptidoglycan, muramyl dipeptide, and lipoteichoic acid), and bacterial products such as staphylococcal enterotoxin B, toxic shock syndrome toxin-1, Pseudomonas exotoxin A, and M protein of hemolytic group A streptococci
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