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6 Cards in this Set

  • Front
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SIRS

2+ of:


Temperature >38 or <36


HR >90


RR >20


WCC >12000 or <4000


SEPSIS - DEFINITION

Known or suspected infection PLUS meeting SIRS criteria

SEVERE SEPSIS

Sepsis with acute organ dysfunction

SEPTIC SHOCK

Inadequate organ perfusion due to severe sepsis causing vasodilation and fall in CO



Failing organ systems which need intervention eg noradrenaline

SEPSIS - PATHOPHYSIOLOGY

Overresponse to infection



Uncontrolled cascade



Microvascular thrombosis, neutrophil rolling and endothelial dysfunction

SEPSIS 6

3 in 3 out


Oxygen


IV antibiotics


IV fluids


Urine output


Blood cultures


Lactate