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10 Cards in this Set
- Front
- Back
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What percentage of people die with sepsis once diagnosed each year in the US?
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30-50%
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This is the circulating WBC responsible for releasing proinflammatory and procoagulant factors when stimulated by tissue released cytokines in sepsis
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monocyte (also macrophage in tissue)
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Necessary endogenous compound for activation of protein C, down regulated in sepsis
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thrombomodulin
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This syndrome is required along with a severe infection to correctly diagnose sepsis
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SIRS - Systemic Inflammatory Response Syndrome
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Low dosages of this compound can prove useful in treating septic shock when traditional vasopressive inotropes prove inadequate
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Vasopressin (ADH)
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In patients with sepsis and hypotension, we should first initiate this therapeutic strategy
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Fluid therapy (fluid challenge)
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As sepsis progresses and becomes more severe, the patient will manifest this syndrome, which may lead evetually to shock and death.
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MODS Multiple organ dysfunction syndrome
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The three physiologic systems always affected in sepsis, which actually progresses the pathology, include:
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Inflammatory system,
coagulantion system, and fibrinolytic systems |
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IN certain disorders including sepsis, both bleeding and coagulation can occur concurrently. This is known as:
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DIC Disseminated Intravascular Coagulopathy
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CHAOS in sepsis refers to an imbalance in immunity, inflammation, and coagulation. What does the A stand for in CHAOS?
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Apoptosis, as blood cells are consumed, apoptosis is accelerated to generate youthful WBCs. However, this is inadequate in sepsis
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