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15 Cards in this Set
- Front
- Back
Approximately 50% of the filtered urea is reabsorbed by the ____ tubule via ____ ____ and ___ mechanisms.
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proximal, transcellular, paracellular simple diffusion
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In the loop of henle, distal tubule and cortical collecting duct urea concentration _____.
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increases
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Urea concentration in the loop of henle increases because of _____ via _____ diffusion.
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secretion, facilitated (created by medullary collecting duct)
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Urea concentration in the distal tubule and collecting duct _____ due to ____.
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increases, urea impermeability and water reabsorption
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Cells of the ____ collecting duct are permeable to urea and favor _____.
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medullary, reabsorption
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The driving force for facilitated diffusion of urea into the loop of henle is created by ____.
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medula collecting ducts reabsorption of urea
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At very low flow rates where water reabsorption is ___, urea excretion is ___.
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high, high (BUN rises)
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Creatine unlike Urea is independent of ____ rate, and therefore BUN to creatine will be ____ during hemorrhage.
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flow, elevated
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Glucose reabsorption is coupled to ____ via the ______ on the apical membrane of the ____.
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Na, Na/glucose cotransporter (SGLT1 & 2), proximal tubule
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Non charged forms of weak acids and bases cross the epithelial membrane through ____.
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passive diffusion
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PTH ____ phosphate reabsorption by _____.
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inhibits, lowering transport maxima (endocytic removal of NaPi tranporters through phosphoryation by PKC and PKA)
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Vitamin D ____ phosphate reabsorption.
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stimulates (increases NaPi transporters)
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Ca is reabsorbed by paracellular mechanisms in the _____ tubule.
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proximal (positive lumen)
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Ca reabsorption in the thick ascending limb and distal tubule through _____ mechanism via ____ on the apical membrane.
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transcellular, ECaC, (basolateral Ca-ATPase and Na/Ca exchanger efflux)
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PTH and vitamin D ____ Ca reabsorption, by ____ and ____, respectively.
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increase, opening apical Ca-channels, Ca-binding protein that decreases ionic Ca favoring influx
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