Sem 4 Week 7 Lecture 5

Front 1

Non declarative learning is also known as

Back 1

Implicit learning

Front 2

Non-declarative learning can be divided into 2 main groups

Back 2

-Non associative learning
-Associative learning

Front 3

Non-associative learning

Back 3

-HABITUATION: reduction in responding to a repeatedly delivered stimulus
-SENSITISATION: enhancement or augmentation of a response produced by the presentation of a strong stimulus

Front 4

Associative learning

Back 4

-Classical Pavlovian conditioning paradigm--> temporal correlation ensures that the conditioned stimulus (bell) provides info abt the unconditioned stimulus (food)
-learning abt relations between events in organism's environment

Front 5

Declarative memory

Back 5

Explicit memory

Front 6

Declarative memory deals with

Back 6

Facts & events

Front 7

Which part of the brain responsible for declarative(explicit memory) ?

Back 7

-Hippocampus
-Medial temporal lobe
-Diencephalon

Front 8

Non associative learning is related to

Back 8

Reflex pathways

Front 9

Basic associative learning is assoc. with

Back 9

-Emotional responses
-Skeletal musculature

Front 10

Region of brain responsible for basic assoc. learning

Back 10

-Amygdala
-Cerebellum

Front 11

What are the 2 other subgroups of Non-declarative learning?

Back 11

-Skills and habits(striatum,motor cortex,cerebellum)
-Priming(neocortex)

Front 12

pt H.M

Back 12

Bilateral resection of medial structures of temporal lobes to treat severe epilepsy

Front 13

Pt H.M

Back 13

-profound impairments of recent memory in absence of other intellectual loss
-able to hold immediate impressions in his mind but as soon as attention diverted,they were lost
-old memories from childhood intact

Front 14

H.M showed improvement

Back 14

in a task involving implicit learning of skilled mvts(but had no explicit of having done the task before)

Front 15

What are the brain areas lesioned in H.M ?

Back 15

-Hippocampus
-Entorhinal cortex
-perirhinal cortex
-Amygdala

Front 16

Entorhinal cortex

Back 16

-an important memory center in the brain
-forms the main input to the hippocampus and is responsible for the pre-processing (familiarity) of the input signals

Front 17

During flashing of pictures at H.M.

Back 17

activation of medial temporal lobe.

Front 18

Hebb's synaptic plasticity

Back 18

-When an axon of cell A excites cell B and repeatedly & persistently takes part in firing it,some growth processes or metabolic changes occur in one or both cells---> A's efficiency as one of the cells firing B is INCREASED.

Front 19

Bliss and Lomo's synaptic plasticity theory:

Back 19

A brief high frequency train of AP within specific inter-neuronal pathways--> increase in synaptic strength(LONG TERM POTENTIATION)

Front 20

In induction of LTP,

Back 20

there is insertion of 1 additional AMPA receptor in post-synaptic terminal.

Front 21

Disorders involving learning & memory deficits

Back 21

-Mental retardation/learning disorders
-Alzheimer's disease
-Dementia
-Huntington's
-Amnesia
-Depression
-Schizo
-Addiction

Front 22

In huntington's,

Back 22

DNA expansion causes brain degeneration.

Front 23

In huntington's mice,

Back 23

Hippocampal LTP deficits

Front 24

What mediates experience-dependent plasticity in healthy and diseased brain ?

Back 24

Gene-environment interactions

Front 25

What delays onset and progression of disease in HD mice ?

Back 25

Environmental enrichment

Front 26

Disruption of synaptic function and plasticity

Back 26

may lead to disorders of learning and memory.