Sem 4 Week 11 Lecture 5

Front 1

Size of breast doesnt represent capacity

Back 1

for lactation.

Front 2

Alveoli converge via milk ducts to

Back 2

Nipples

Front 3

Epithelial cells

Back 3

produce milk

Front 4

Myoepithelial cells

Back 4

Contract to eject milk

Front 5

Estrogen

Back 5

Duct growth

Front 6

Progesterone

Back 6

Gland growth

Front 7

Terminal alveoli are called

Back 7

Mammary gland lobules

Front 8

Before puberty,

Back 8

no glandular tissue(immature breasts ,rudimentary duct-like structures)

Front 9

Then,under influence of O & P,

Back 9

mature non-pregnant breasts with ducts + alveoli(small & NON SECRETORY)

Front 10

Then under influence of O,P and prolactin,placental hormones,

Back 10

branching of ducts + enlargement of alveoli(still not secretory because oestradiol & Progesterone PREVENT IT)

Front 11

PRL conc. before puberty

Back 11

LOW(Prolactin Inhibiting hormone from hypothalamus is dominant)

Front 12

Estrogen has inhibitory actions on

Back 12

PIH(dopamine)--> allow PRL to increase.

Front 13

Stimulation of mammary growth

Back 13

-PRL
-Estrogen
-Progesterone
-hCG
-hCSsomatomammotropin
-placental lactogen

Front 14

PRL

Back 14

-critical for milk production
-mammary growth/dev.
-generates enz. for milk production at parturition.

Front 15

During pregnancy,

Back 15

-Oxytocin:increase sensitivity of myoepithelial cells
-estrogen: stimulates PRL release & blocks action of PRL
-Progesterone : blocks action of PRL

Front 16

During pregnancy,breasts are ready to work but can't produce milk until

Back 16

Oestrogen and Progesterone removed after delivery of baby.

Front 17

PRL released after birth is released in response to

Back 17

Suckling

Front 18

At parturition,

Back 18

PRL levels fall to basal levels.

Front 19

Milk production

Back 19

PRL

Front 20

Milk ejection

Back 20

Oxytocin

Front 21

Baby suckling produce milk for

Back 21

NEXT feed

Front 22

Hormones that play a permissive role in milk production

Back 22

-cortisol
-insulin
-parathyroid hormone
-GH

Front 23

Oxytocin acts on uterus to

Back 23

return it to normal size.

Front 24

Lacatating woman will have milk let down even when

Back 24

baby is not crying.

Front 25

Milk letdown usually stimulated by

Back 25

Baby crying

Front 26

Stress inhibits

Back 26

Ovulation--> decreased GnRH--> decreased LH and FSH--> no build up of endothelial lining--> no ovulation.

Front 27

Oxytocin acts on

Back 27

Contraction of myoepithelial cells.

Front 28

Colostrum

Back 28

-first 40 hrs(upto 3 days)
-thicker in consistency
-precursor to breast milk

Front 29

Compared to breast milk,colostrum has high conc. of

Back 29

-Proteins
-Sodium
-Chloride
-Fat-soluble vitamins
-Antibodies

Front 30

and low conc. of

Back 30

-lactose
-K+
-Fat
-Water soluble vitamins

Front 31

Breast milk contains

Back 31

-water
-protein
-fat
-lactose
-vitamins
-minerals
-immunol. qualities

Front 32

Benefits of breast milk

Back 32

-Best nutrition
-Protection from infections(gatsro)
-Mother infant bonding
-uterine involution
-decreased breast cancer
-decreased SIDS
-contraception

Front 33

Complete infertility during

Back 33

Lactational amenorrhea

Front 34

Frequency

Back 34

of feeding is crucial in the above(every 2-4 hrs)

Front 35

What kind of pill used in lactating women for contraception ?

Back 35

Progesterone

Front 36

Women dont ovulate during pregnancy as

Back 36

O & P have inhibited GnRH

Front 37

Suckling inhibits

Back 37

GnRH

Front 38

Usually you ovulate before you menstruate.

Back 38

True