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5 Cards in this Set

  • Front
  • Back
Increase in serum LDL above 190mg/dl
Acquired causes
primary hypothyroidism
Nephrotic syndrome
type II
A type II, familial lipoprotein disorder
Autosomal dominate
Defiency in LDL receptors
familial hypercholesterolemia
A..Famial dysbetalipoproteinemia (remnant disease)
B. Defiency of apolipoprotein E
1) Decreased liver uptake of chylomicron remants and IDL
Increased serum chlesterol and triglycerides
Type 3 .Famial dysbetalipoproteinemia (remnant disease)
a. increase in VLDL due to increase in synthesis or decreased catabolism
b. Acquired causes: Excess alcohol, progesterone OC, DM
c. Familial. Autosomal dominate
Type 4, most common
a) Autosomal dominant
b) defiency in apolipoprotein B-48 and B-100 1) Defiency in chylomicrons, VLDL, and LDL 2) Decrease in serum cholestorl and triglycerides.
Apolipoprotein B deficiency (abetalipoprteinemia) Type 5
Characterized by malabsorption, vitamin E defiency
ataxia, hemolytic anemia with thory RBCs (acanthocytes.