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5 Cards in this Set
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Increase in serum LDL above 190mg/dl
Acquired causes primary hypothyroidism Nephrotic syndrome |
type II
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A type II, familial lipoprotein disorder
Autosomal dominate Defiency in LDL receptors |
familial hypercholesterolemia
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A..Famial dysbetalipoproteinemia (remnant disease)
B. Defiency of apolipoprotein E 1) Decreased liver uptake of chylomicron remants and IDL Increased serum chlesterol and triglycerides |
Type 3 .Famial dysbetalipoproteinemia (remnant disease)
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a. increase in VLDL due to increase in synthesis or decreased catabolism
b. Acquired causes: Excess alcohol, progesterone OC, DM c. Familial. Autosomal dominate |
Type 4, most common
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a) Autosomal dominant
b) defiency in apolipoprotein B-48 and B-100 1) Defiency in chylomicrons, VLDL, and LDL 2) Decrease in serum cholestorl and triglycerides. |
Apolipoprotein B deficiency (abetalipoprteinemia) Type 5
Characterized by malabsorption, vitamin E defiency ataxia, hemolytic anemia with thory RBCs (acanthocytes. |