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13 Cards in this Set

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What is a seizure

Transient occurrence of signs and symptoms resulting from abnormal excessive or synchronous neuronal activity in the brain

What are the classifications for epileptic seizures

Two main-Focal and generalised seizures


Febrile seizures


Reflex seizures


Acute symptomatic seizures


Unprovoked seizures


Remote symptomatic seizures

Focal seizures

Seizures with EEG changes suggesting limitation to one cerebral hemisphere


1 with and without loss of consciousness

What are generalised seizures

Seizures with EEG changes suggesting synchronous involvement of all or both hemispheres

What is a Febrile seizure

Seizures occurring in 6months to 6 year olds which are associated with temperatures greater than 38 degrees that are not the results of CNS infection or any metabolic imbalance in the absence of a history of afebrile seizure

Classification of Febrile seizures

Simple febrile- primary generalised tonic clonic seizures associated with fever which do not last greater than 15 minutes not recurring withing 24 hours with a positive family history, no permanent EEG changes seen


Complex- focal seizures which are prolonged greater than 15 minutes recurring withing 24 hours and no positive family history, risk of epilepsy.

Investigations in a convulsing child

Random blood sugar


Full blood count


Septic screen


Lumbar puncture


EEG


Imaging CT

Causes of convulsions in the child

Neonatal period


Hypoglycemia


Hypocalemia


Hypoxic ischemic encephalopathy


CNS infection


Septicemia


Inborn errors of metabolism


Developmental malformations


Pyridoxine dependency


Intracranial bleeding


POSTNEONATAL


Febrile convulsions


Epilepsy syndrome


CNS infections


Metabolic causes


Space occupying lesion


Drugs: Phenytoin carbon monoxide salicyclates


Manage the convulsion

Secure an airway


Administer O2 via mask or nasal prongs


Ensure circulatory access and start IV fluids


Check RBS and treat if hypoglycemic


Take bloods for culture and sensitivity


Abort seizure with Phenobarbital


Rule out CNS infections

What is status epilepticus

Prolonged single seizures or multiple seizures occurring for greater than 30 minutes without regaining of consciousness in between

What is impending status epilepticus

Any seizure lasting greater than 5 minutes

Complications of status epilepticus

Mental retardation


Focal neurological deficits


Behavorial disorders


Clonic epilepsy

First line antiepileptics and side effects

Carbamazepine - hepatitis, rash, GI symptoms


Phenytoin- Hirsutism, gingival hyperplasia, hypercalcemia, nystagmus


Sodium valproate- hepatic necrosis


Phenobarbital- hypoventilation


Ethosuximide- photophobia, leukopenia, drug dyscrasia


Lamotrigine- Stevens-Johnson Syndrome