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15 Cards in this Set
- Front
- Back
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DOC for partial (simple and complex) as well as tonic-clonic seizures
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carbamazepine
phenytoin valproic acid |
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4 other drugs useful for tonic clonic seixures
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lamotrigine
topiramate valproic acid gabapentin |
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DOC for absence seizures
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ethosuximide
(also valproic acid) |
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used to treat status epilepticus
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benzodiazepine
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eclampsia
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Mg sulfate (benzo if refractory)
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common AE of epilepsy drugs
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diplopia, sedation, ataxia, nystagmus, dizziness
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AE of phenytoin
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gingival hyperplasia, hirsutism, getal hydantoin syndrome (cleft lip, congenital heart Dz, MR)
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which ani-epileptics are teratogens
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phenytoin, carbamazepine, valproic acid
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valproic acid results in what birth defect?
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spina bifida
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what seizure drugs cause SJS
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ethosuximide
lamotrigine carbamazepine phenytoin phenobarbitol |
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which seizure meds cause agranulocytosis
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carbazepine
(other drugs: clozipine, colchicine, PTU, methimazole) |
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hepatotoxic anti-epileptic
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valproic acid
carbamazepine |
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which drugs inhibit P450 (BCG PQRS)
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barbs
carbamazepine griseofulvin phenytoin quinidine rifampin St john's wort |
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which anti-epileptics block Na+ chanels
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carbamazepine
phenytoin lamotrigine topiramate valproic acid |
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which anti-epileptics work by potentiating the inhibitory effects of GABA
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valproic acid, barbs, benzos, gabapentin, topirimate
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