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12 Cards in this Set

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The reduction of circulating hemoglobin resulting in a decrease in oxygen-carrying capacity of the red blood cells (RBCs).
Anemia
What are 4 causes of anemia?
1. Impaired or decreased production of RBCs
2. Nutritional deficiencies
3. Metabolic disturbances
4. Increased erythocyte destruction
What lab value is the true indicator of the physiological potential of blood to transport oxygen to tissue?
Hemoglobin
What is the difference b/t direct and indirect Coombs testing?
Direct Coombs test identifies antibodies on the SURFACE OF THE RED CELLS whereas Indirect Coombs identifies antibodies in the SERUM
What is the standard treatment for anemia?
LR, IR, PRBC transfusion of 10 ml/kg
Children receiving radiation therapy need to maintain hemoglobin levels of ____or higher to get maximum benefit from therapy.
10 gm/dL
What is considered neutropenia for an infant up to 2 yo?
ANC 1000 or less
What is considered neutropenia in children greater than 2 yo?
ANC 1500 or less
The risk for serious bacterial infection is increase when the ANC is below?
500
How is ANC calculated?
(%bands+%segs) x WBC
A patient with F/N should have the following diagnostic work up done:
1. History and PE
2. Blood cultures from all lumens and possibly peripheral
3. UA and urine culture
4. Stool cx (if diarrhea present)
5. CXR (at discretion of the provider)
What is the recommended dose and duration of treatment for GCSF following chemotherapy?
5-10 micrograms/kg starting 1-5 days post chemotherapy x 10-14 days