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30 Cards in this Set

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Terpenes

Largest group of secondary metabolites


Structure based around 5 carbon isoprene units


Help plants adapt and thrive in environment


Helps plants make them more disease resistant


Some by attracting pollinators


Some by promoting growth


Terpenes from yew tree formed taxol which is a chemotherapy drug. Terpenes from sweet Annie is found to treat malaria. The specific terpene is called Artemisinin


Monoterpenes

Menthol - peppermint


Borneol - rosemary


Pinene - pine


Thymol - thyme


Linalool - lavender


Mucolytic


Antiseptic


Anti microbial


Decongestant


Stimulant


Tonic activity

2 isoprene units

Iridoids

Adapted monoterpene


Bitter tasting


Prime the digestive system to promote digestive secretions


Most bitter herbs will have iridoids


Iridoids that form glycosides are sedatives, antimicrobials, mucolytes, diuretics and laxatives



Sesquiterpenes

Combines with lactone forms sesquiterpene lactones.


Antimicrobial


Anti inflammatory


Cardio protective


Immunostipulants


Tumour inhibition


Cytotoxic


Chamazulene - lowers fever and is anti inflammatory found in Chamomile & Yarrow. Makes essential oils blue


Zingiberne - digestive and stomach calming found in ginger.

3 isoprene units

Sesquiterpene lactone

Alantolactone - found in elecampane is an expectorant, cholagogue, antimicrobial and urinary antiseptic


Parthenolide - found in feverfew is an antimicrobial and anti migraine


Diterpenes

Cardio vascular tonics


Pain relieving


Anti inflammatory


Anti microbial


Anti fungal


Expectorant


Some are bitter: carnosal disterpene is found in sage and ginkgolide disterpene is found in ginkgo Biloba


Grindelic avid found in Grindelia contributes to respiratory use and marrubin found in white horsechestnut is an expectorant

4 isoprene units

Saponis

Foam in water


Soapwart


Wild yam


Liquorice


Astragalus


Marigold


Blue cohosh


Poke root


Dandelion


High saponins are said to protect plant from disease


Expectorant


Anti microbial


Anti fungal


Anthelmintic


Strengthens capillaries


Adaptogenic


Tonic


Immunomodulating


Hormone balancing


Cholesterol lowering


Liver protecting


Emetic in high doses


Irritant of the mucous membranes

Containes 6 isoprene units

Triterpenoid Saponins

Have active constituents such as:


Aescin


Glycyrrhizin


Glycyrrhetic acid


Steroidal saponins


Aescin

Tonic effect and strengthening blood vessels


Horse chestnut tree conkers cream helps piles and varicose veins


Glycyrrhizin

Liquorice


Very sweet


Stimulates activity of interferons which are anti viral agents and immune response


Expectorant


Antiulcerogenic


Glycyrrhetic Acid

Antiulcerogenic


Anti inflammatory


Mineralocorticoid action


People with high blood pressure are given liquorice


Glycyrrhetic Acid

Antiulcerogenic


Anti inflammatory


Mineralocorticoid action


People with high blood pressure are given liquorice


Steroidal Saponins

Used to make foam in extinguishers


Tonic for cardio vascular system


Lily of the valley and foxglove have a long history of heart medication


Diasgenin found in fenugeek, bethroot and wild yam help produce steroidal molecules like progesterone


Resins

Produced by trees


Pine resin is common, acts like a sealant, glue varnish.


Pine resin good for wounds as it is antiseptic and anti inflammatory. Also good for eczema.


Damiana resin has nervine properties


Myrrh is antimicrobial


Grindelia is an expectorant


Best medium to use with resin is a strong alcohol.


Oleoresins

Resins mixed with volatile/essential oils found in trees


Turpentine is an oleoresin that has a very pungent odour.


Oleoresins are also found in Ginger.


Ginger tincture needs high percentage of alcohol to extrct the oleoresin




Balsams

Resins mixed with constituents


Example are cinnamic or benzonic acid esters.


Most commonly used balsam is Tolu balsam which is used in cough syrups and cough sweets


Gum Resins

This is the amalgamation of resins with gum which are extracted from plants such as myrrh.




Polyphenols

Phenolic compounds are the sensory character to herbs, they contribute to colour & flavour.


The colour of a plant is a polyphenol, the taste is an iridoid terpene, small is the monoterpene.


Polyphenols are grouped according to the number of carbon atoms present.


Antimicrobial and antiseptic, was the first surgical antiseptic

taste, smell, colour
Salicin

Analgestic polyphenol found in meadowsweet and willow.


Doesnt cause gastric irritation like asprin.


Anti inflammatory, anti rheumatic and often given to people with joint issues.


Salicylic acid is associated with gastric issues.

Pain killer

Arbutin


Small polyphenol molecule


Found in bilberry and bearberry


Is antimicrobial and renowned for urinary antiseptic properties.


Gallic Acid

Phenolic acid primarily known as an astringent.


Anti inflammatory


anti microbial


and opens up the airways


Usnic acid

Phenolic acid which is found in linchen usnea


Antibactieral


Phenylpropanoids

Very fragrant


Anethole found in fennel and anise - antispasmodic


Myristian found in nutmeg, cinnamon and parsley - hallucinogen


Curcumin found in turmeric - anti inflammatory and anti cancer properties


Coumarins

Fragrant phenylpropanoid similar to cut grass.


Found in meadow sweet leaves, melilot (anti inflammatory, vascular tonic) sweet woodruff, red clover, angelica (anti spasmodic) horse chestnut (anti inflammatory, vascular tonic).


Coumarins have vascular tonic nature




Quinones

Type of polyphenol


Red, yellow, orange and sometimes black


Plants such as madder root and alkanet often used as dyes


Napthoquinones

Type of quinone


has yellow pigments found in henna dye


contributes to laxative action


antimicrobian properties


Sundews napthoquinone is plumbagin


Pav D'arco's napthoquinone is lapachol


Anthraquinones


Are a powerful laxative found in Aloe, Senna, Buckthorn and Cascara Sagrada.


Work by stimulating and irritating the digestive lining and the body reacts by trying to expel the contents.


Not to be given to pregnant women.


One of St Johns Wort's active contituents ia an anthraquinone called Hypercin - Hypercin has anti viral properties.


Not all contituents within a groupd need to behave the same




Flavonoids

Two phenyl rings & a heterocylic ring connected by carbon atoms.


Often combine with other molecules and may have a different name, other names include:


flavones


isoflavones


catechins


anthocyanidins


flavanonols


flavanones


Anthocyanidins causes the blue andred in berries and petals and is a flavonoid


For someone who needs an increase in flavonoids herbalists will give marigold, violets, red clover, yarrow, hawthorn, shepherds purse and berries such as bilberries and elderberries.



Share c6-c3-c6 structure
Flavonoid therapeutic action





antioxidant


stengthening to capillaries and larger blood vessels


anti inflammatry


sedative


antispasmodic


immunomodulating


cardi-modulators


connective tissue regenerators


liver protectors


cholagogues


diuretics


antimicrobials


antineoplastics


Best known for their abililty to strengthen and protect the cardiovascular system


The best are oligomeric procyaniclins found in berries, in particular bilberries as they help manage inflammation, rebuild collagen which is damaged by extensive inflammation and helo modulate the immune system




Tannins

Astringent


2 categories: condensed (proanthyocyanidins) and hydrolysable.


Tannins tone and tighten mucous membranes by precipitating the proteins present in the membranes and can refuce secretions


Treat:


Diarrhoea


reduce inflammation


reduce mucous productions


used internally and externally to manage bleeding


Can interact with:


polysaccharides, carbohydrates, cell membranes and microbes and with enzymes.


Can hibit microbes and enzymes with a high concentration.


Do not give a high dose of astringent for too long



used to tan leather