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213 Cards in this Set

  • Front
  • Back
the coelom is an embryonic cavity that divids into:

(4)
1. pericardial cavity

2 and 3: pleural cavities

4. peritoneal cavity
what do the pleuropericardial folds do?

(2)
1. separate the pleural and pericardial cavities

2. produce fibrous pericardium
what do the pleuroperitoneal membranes do?
1. partition the pleural and peritoneal cavities

2. contribute to the diaphragm
the right and left sides of the ceolom are brought together via:
body folding

- dorsal mesentery now in between the two sides
the somatic LPM is found laterally, on both sides of the ceolom; it forms:
the parietal serous membrane
the splanchnic LPM, found medially, forms the:
visceral serous membrane
after being brought caudally, the septum transversum separates:
the primitive pericardial cavity from the primitive peritoneal cavity

- ***pericardioperitoneal canals connect the two and provide continuity***
mesoderm covering the lung buds =>
visceral pleura
phrenic nerves are contained within:
pleuropericardial folds
***what forms the fibrous membrane?***
***pleuropericardial folds*** fused together
what are the 4 structures that make up the diaphragm?
1. septum transversum

2. mesentery of esophagus

3. pleuroperitoneal membrane

4. myoblasts from body wall / C3-C5 somites
**Congenital Diaphragmatic Hernia =
failure of pleuroperitoneal folds to close

- generally occurs on left side

- contents of abdomen come up into thorax

=> lung can't develop as well
multiple rib fractures (2 or more ribs broken in 2 places) =>
flail chest with paradoxical movement
paradoxical movement =
breathe in - rib segments come out

- breathe out ==> rib segments come in
thoracic outlet syndrome =
compression of neurovascularture due to narrowed thoracic aperture
thoracic aperture is bounded by:
sternum, vertebra, and first ribs
stypmtoms of TOS =

(3)
1. pain in neck and shoulder

2. numbness/weakness

3. decreased pulse
causes of TOS =
trauma, cervical rib, other things
example of a type of TOS:
costoclavicular syndrome
treatment for TOS =

(2)
1. PT (usually)

2. surgery (occasionally)
11 intercostal spaces and 1 subcostal - IC space 1 is under:
rib 1,

and so on
sternal angle is found at
rib 2

- used to locate 2nd IC space
IC VAN travels within:
costal groove, on inferior aspect of every rib
main action of all intercostal muscles =
keep ribcage stable during breathing
external IC's :

(2)
1. down and in

2. function during inspiration - *elevate* the ribs
internal IC's:

(2)
1. down and out

2. funtion during expiration; depress the ribs
(innermost intercostals ~
vertical orientation)
***ALL intercostals are innervated by:***
IC nerves 1 - 11
subcostal muscles:

(2)
1. found posteriorly

2. depress the ribs
transversus thoracis:

(2)
1. found inside anterior aspect of rib cage

2. depress costal cartilage
IC nerves =
ventral rami

- and therefore contain all 4 somatic/autonomic types
T2 ~
intercostobrachial nerve - cutaneous to medial arm

(called the lateral cutaneous branch of T2)
T3 through T6 are:
typical IC nerves
T7 - T11 innervate:
the abdominal wall
T12 =
subcostal nerve
***T4 dermatome ~
plane of nipples
***T10 dermatome ~
plane of belly button
***IC nerve block: preferred site of injection*** =
**costal angle (that is, posterior thorax)**
needle decompression =
removal of fluid (air or liquid) from lungs

- **MUST avoid IC VAN)**
***preferred sites for needle decompression =

(3)
2nd, 3rd, or 5th IC space
anterior IC arteries: 2 sources of origin:
upper 6 originate from internal thoracic artery

lower 5, from the musculophrenic artery
posterior IC arteries: 2 sources of origin:
upper 2 originate at the superior thoracic artery,

lower 9 from the thoracic aorta
3 major branches of the internal thoracic artery:
1. anterior IC's (1-6)

2. superior epigastric artery

3. musculophrenic artery
IC veins drain into:
azygous and hemiazygous veins => vena cavae
the pleural cavities are separated by:
the mediastinum (cavity)
pleural cavities are lined by:
the pleura - outer parietal, inner visceral, and potential space in b/w
superior mediastinum = area above
T4/T5
the superior mediastinum contains:

(5)
1. thymus

2. great vessels

3. trachea

4. esophagus

5. nerves
inferior mediastinum =
anterior, middle, and posterior mediastinums
the anterior mediastinum is very
small
middle mediastinum contains:

(2)
1. heart

2. origin of greater vessels
the posterior mediastinum contains:

(4)
1. aorta

2. thoracic duct

3. azygous/hemiazygous

4. sympathetic trunks
middle mediastinum also called:
Thorax 2

- posterior mediastinum also called Thorax 3
***4 masses of the anterior mediastinum:***
1. enlarged thymus

2. enlarged thyroid

3. teratoma

4. lymphoma
***middle mediastinum masses:***

(4)
1. lymph nodes

2. aortic aneurysm

3. vascular dilation

4. cysts
****signs and symptoms of both anterior and middle mediastinal masses:****
1. retrosternal pain

2. cough/dyspnea

3. SVC syndrome

4. choking sensation
pericardium is double-walled;

external portion =

internal portion =
external = fibrous pericardium

internal = serous pericardium
fibrous pericardium:

(2)
1. sticks to diaphragm and sternum along with serous pericardium

2. pain is conveyed by the phrenic nerve
serous pericardium also consists of 2 layers:
1. parietal

2. visceral


also has a potential space
***visceral serous pericardium is also called:***
epicardium
***what does the transverse pericardial sinus do?***
**separates arteries from veins**
***how is the oblique pericardial sinus formed?***
by reflection onto the pulmonary veins of the heart
***cardiac tamponade =
**blood** in the pericardial space => heart can't fully expand
signs of cardiac tamponade:

(3)
1. engorgement of jugular vein

2. muffled heart sounds

3. dec. in diff. between systolic and diastolic BP
pericardiocentesis =
drainage of blood to treat cardiac tamponade

- occurs in IC space near sternum
axillary tail =
lateral extension of the breast
line of nipples ~
4th IC space
breasts consist of:

(3)
1. glandular tissue

2. adipose

3. CT septa
another name for glandular tissue =
mammary glands
areola =
area around nipple
glandular tissue =
10-20 lobes, each with lactiferous duct and lactiferous sinus
retromammary space =
loose CT that separates breasts from fascia of pec major and serratus anterior
what attaches mammary glands to the overlying dermis?
suspensory ligaments
metastasis =
spread
BC uses
the lymph system to spread
***axillary nodes ~
75% of lymph drainage of the breast
25% of lymph drainage of breast occurs via:

(3)
1. parasternal lymph nodes (medial)

2. opposite breast (~***spread of cancer***)

3. abdominal nodes
20-30 axillary nodes are divided into 5 groups:
1. ***pectoral/anterior***

2. humeral/lateral

3. subscapular/posterior

4. central

5. apical
***which collection of nodes receives the majority of lymph from breast tissue?***
the **pectoral/anterior** nodes
***which lymph collection receives lymph from all the other ones?***
the **apical nodes**
all nodes drain to apical nodes =>
right lymphatic or left thoracic duct => venous system
BC => tumor => block of lymph channels => edema =>
"orange peel" look of overlying skin
what causes nipple retraction/deviation or dimpling of breast tissue?
tumor pulls on suspensory ligaments
mastectomy ~ potential for:
damage to long thoracic nerve => winged scapula
coronary sulcus =
sulcus between atria and ventricles

- encircles the heart
the right coronary artery is found in:
the coronary sulcus
3 main branches of the right coronary artery:
1. branch to SA node

2. acute marginal branch

3. posterior interventricular artery
the left coronary artery is also called:
the left main artery
3 branches of the left main artery (left coronary):
1. anterior interventricular (LAD)

2. circumflex

3. obtuse marginal
LAD =
left anterior descending
***the left coronary artery supplies:***

(4)
1. most of LA

2. most of LV

3. most of the septum

4. AV bundles
vessels used for coronary artery bypass grafts (CABG):

(3)
1. great saphenous vien (watch for valves)

2. internal thoracic artery

3. radial artery
***coronary sinus corresponds to:***
veins
venae cordis minimae drain into atria ________
directly
what is the septomarginal trabecula, and what is it unique to?
septal limb + moderator band;

unique to the RV
tricuspid valves' names =
anterior, posterior, and septal
papillary muscles ~
*passive* shutting of valves via pressure difference
papillary muscles connect:
chorda tendinae to myocardium

- chordae tendinae attach to valves
pulmonary valve (off of RV) ~
3 semilunar cusps

as is the aortic valve
mitral valve leaflet names' =
anterior and posterior
hyperplasia =
inc. in amount of cells
LV hypertrophy = result of:

(2)
1. HTN

2. aortic/mitral valve disease
all of the valves are in the same:
plane
50% of the time, the artery failure that causes MI =
LAD artery
***cardiac skeleton =
rigid CT around each valve
***purposes of cardiac skeleton =

(2)
1. attachement site for cusps

2. barrier to electrical activity from atria to ventricles
2 types of infacrts:
1. transmural

2. subendocardial
subendocardial infarct =
infarct limited to interior 1/3 of the ventricular wall
transmural infarct =
infarct across the entire ventricular wall
blood carries
sound
auscultory locations: pulmonary valve ~
left, 2nd IC space, just lateral to sternum
auscultory locations: aortic valve ~
right, 2nd IC space, just lateral to sternum
auscultory locations: tricuspid valve ~
lower part of sternum, slightly left
auscultory locations: mitral valve ~
left, 5th IC space, away from sternum
SA node (pacemaker) =>
AV node (pause) => Bundle of His (in septum) => Purkinje fibers (around ventricles)
cardiac plexus =
collection of parasympathetic and sympathetic nerves

- located at bifucation of trachea, just superior to heart
**lub =

(S1)
closing of AV valves
**dub =

(S2)
closing of semilunar valves

(pulmonic, aortic)
heat initiates its own heart rate; the ANS:
modifies it
in the embryo: blood islands, located cranially, coalesce to form:
*2* endocardial tubes => fusion => heart tube
myocardium secretes:
cardiac jelly

- helps heart beat during development
layers of the heart:

(5)
fibrous membrane =>

check
what is the outermost layer of the heart?
epicardium
another name for epicardium =
visceral pericardium

check
crista terminalis =
crest that separates pectinali muscles from sinus venarum

**in RA**
***septum transversum =>***
***epi***cardium
4 main regions of the heart =
1. bulbous cordis (truncus and conus arteriosus)

2. ventricle (becomes 2 ventricles)

3. atrium (becomes 2 atria)

4. sinus venosus
***truncus arteriosus becomes:
great vessels
***conus arteriosus becomes:
outflow of **ventricles**
the sinus venosus becomes:
the sinus venarum of the RA
where does the septum primum grow?
in the common atrium, partially separating it into two parts
***what grows to the right of the septum primum?***
the septum secundum
***what is the opening of the septum secondum?***
the foramen ovale

(flow goes through foramen secundum afterward)
***septum primum =
valve for the foramen ovale
**myocardium is formed from:
***endocardium*** (innermost layer)
atrial septal defects =
defects in the development of septum primum or secundum
atrial septal defects are found in most:
chromosomal abnormalities
what partitions the AV canal into 2 AV canals (in the embryo)?
endocardial cushions
muscular IV septum begins growing from the bottom - first stage.

second stage =
conotruncal cushions fuse with this muscular septum, creating the final IV septum
Tetralogy of Fallot is the most common:
cause of cyanotic heart disease
symptoms of Tetralogy of Fallot:

(4)
1, pulmonary stenosis

2. overriding aorta

3. IV septal defect

4. RV hypertrophy
common cause of heart defects =
incomplete septation
phrenic nerve:

(3)
1. on both sides

2. *between* parietal pleura and pericardium

3. has motor AND sensory components
the somatic motor portion of the phrenic nerve innervates:
the diaphragm
the general sensory portion of the phrenic nerve innervates:

(3)
1. *central* diaphragm

2. mediastinal pleura

3. pericardium
***lower/lateral aspects of the diaphragm are innervated by:***
lower IC nerves - especially costal pleura

(sensory ONLY - somatic motor of phrenic controls all muscular funtion)
prime muscles of inspiration =

(2)
1. diaphragm

2. external IC's
accessory muscles of inspiration =

(2)
SCM, scalenes
major drive of inspiration =
**relaxation of lungs and ribs (a passive process)
*forced* expiration is accomplished by:

(2)
1. internal IC's

2. abdominals
**parietal pleura is innervated by a general sensory nerve; this means:
it's sensitive to pain
the visceral pleura is innervated by:
a VSN

- doesn't feel pain
what reflects at the hilum?
mediastinal parietal pleura

- enclosing vessels in roots and becoming visceral pleura
lung don't fill entire cavity => pleural recesses. what are their names?

(3)
contodiaphragmatic (one on each side)

and

costomedial recess (on **left**)
**expansion into the pleural recesses occurs during:***
**forced** inspiration
simple pneumothorax =
air in pleural cavity

- can be open or closed
open pneumothorax ~
air entered form outside
closed pneumothorax ~
air came form lung itself
tension pneumothorax =
air enters pleural cavity on each inspiration, but can't exit

=> ST adhering visceral pleura to lung is broken

=> **lung collapses** due to natural elasticity
symptoms of tension pneumothorax:

(3)
1. diminished breath sounds on affected side

2. distended neck veins

3. **tracheal deviation**
treatment of tension pneumothorax =

(2)
needle decompression (to make it simple pneumothorax)

or chest tube
right lung:

(2)
3 lobes (sup, middle, inf),

2 fissures (horizontal and oblique)
left lung:

(3)
2 lobes, 1 (oblique) fissure, 1 lingula
**right main bronchus is wider and straighter:** =>
inhaled foreign bodies tend to lodge here
how should lungs look on x-rays?
*black*
COPD =

(3)
chronic bronchitis, asthma, or emphysema
emphysema =
permanent enlargement of airways/destruction of bronchiole walls by inflammation
effect of emphysema:
**decreased elasticity of lungs** => airways collapse during expiration => patients have to force air out => barrel chest due to hypertrophy of internal IC's
**idiopathic pulmonary fibrosis** =
chronic, restrictive lung disease

- CT squeezes alveoli => hard to get air ***IN***
2 facets of idiopathic pulm fibrosis:
1. men affected more than women

2. diagnosed b/w 30 and 50 years
bronchopulmonary segments: each gets its own:

(2)
1. segmental bronchus

2. pulmonary artery


- but veins run *in between*
each bronchopulmonary segment is:
functionally independent

- can remove one without affecting rest of lung
what do pulmonary arteries carry?**
de-oxygenated blood
pulmonary embolism occurs because:
lungs naturally filter blood clots
95% of the time, thromboemboli originate from:
deep leg veins
3 major causes of pulmonary embolism:
1. venous stasis

2. trauma

3. **coagulation** disorders
60% of pulm embolisms are small - called:
silent pulm. embolisms
symptoms of lesser pulmonary embolism:

(4)
1. tachypnea

2. anxiety

3. dyspnea

4. vague substernal pressure
massive embolization =>
occlusion of vessels => infarct
bronchiol arteries come off of
aorta or its branches

- run with bronchi, provide O2 to pulmonary tissue
where do bronchiol veins drain into?
the azygous system
the pulmonary plexus ~
the cardiac plexus
the vagus nerve is ______ than the phrenic
deeper
superficial and deep lymph nodes of the lungs drain into:
the tracheobronchiol lymph nodes

=> **bronchomediastinal** trunks
signs/symptoms of posterior medistinal masses =

(3)
1. pain

2. neurologic symptoms

3. difficulty swallowing
esophagus is innervated by:
both sympathetic AND parasympathetic nerves
azygous vein:

(3)
1. ~ **right** side

2. receives all right IC veins

3. empties into **SVC**
hemiazygous vein:

(2)
1. *left* side

2. receives lower 4 *post.* IC veins
accessory hemiazygous vein:

(2)
1. left side

2. receives *middle* 4 *posterior* IC nerves
the thoracic duct is located between:
the aorta and the azygous vein

- runs up the esophagus, ends up on the left side on top
thoracic splanchnic nerves innervate:
organs of the abdomen
what keeps the diaphragm alive?
C3, C4, C5
paranchyma =
lung tissue
left lobes officially has ____ segments
8

- right has 10
foregut =
tube that will form parts of the digestive system
respiratory diverticulum =
ventral outpocketing of foregut
the respiratory diverticulum will become:

(2)
1. trachea

2. lungs
what separates the respiratory diverticulum from the foregut?
the ***tracheoesophageal*** ridge

**which means it will separate trachea from esophagus**
the distal end of the respiratory diverticulum becomes:
the lungs buds

- rest of it becomes trachea
the tracheoesophageal septum may fail to form in the proper location; ==>

(2)
1. esophageal fistula

2. esophageal atresia
fistula =
abnormal opening
atresia =
abnormal closure
**only the *lining* of the respiratory tree comes from the:
endoderm

- the remaining tissues come from the ***splanchnic mesoderm***
what directs the branching of the bronchial buds?
**the splanchnic mesoderm**

=> primary, secondary, and tertiary bronchi

- completed in childhood
alveoli go from cuboidal cells to
flat cells
**the diaphragm is HIGH;**
"chest" trauma can actually be an abdominal injury
**lungs are big** - found above:
clavicles, and below xiphoid
the heart takes up a lot of
space in the chest
3 risks of subclavian venous line placement:
1. pneumothorax

2. subclavian artery injury

3. brachial plexus injury
to pinpoint needle decmpression:
mid-calvicular line by 2nd IC space
what do chest tubes do?
drain blood from the lungs
X-ray: Span of heart (cardiac silhouette) should be less than half:
the diameter of the thorax
- If greater, it’s probably a cardiomegaly or pericardial effusion
x-ray: a sharp border is probably formed by a:
fissure

=> Fissure ~ volume loss

=> pneumothorax, hemothorax