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24 Cards in this Set
- Front
- Back
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What are the gonads initial appearance in an embryo?
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genital ridges
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Where do primordial germ cells originate? Where do they move?
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Yolk sac, move to genital ridges
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What two tissue types make up the formative gonads?
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intermediate mesoderm and coelomic epithelium (splanchnic LPM)
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What grows from the coelomic epithelium and penetrates the underlying mesenchyme (intermediate mesoderm)?
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Primitive sex cords
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In males, what happens with the sex cords?
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They turn into testis cords and pinch off, forming seminiferous tubules and rete testis.
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What is responsible for producing testosterone? What week?
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Interstitial cells of Leydig Week 8
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The mesonephric (Wolffian) duct is left around in males. What does it become?
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Vas deferens and epididymis
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What do the mesonephric tubules become in males?
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Efferent ductules (connect epididymis and testes
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What germ layer do the prostate and bulbourethral glands originate from?
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endoderm of urogenital sinus
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Where do the seminal vesicles branch from?
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Mesonephric ducts (future vas deferens)
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After primitive sex cords develop in the ovary, what happens to them?
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Dissociate and corticol cords take their place (which go on to form follicular cells)
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Which duct largely degenerates in females?
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Mesonephric (Wolffian) ducts
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Which duct largely degenerates in males?
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Paramesonephric ducts
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What two purposes do the paramesonephric ducts serve?
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Form P. tubercle to connect uterovaginal canal; also forms uterine tubes (fallopian tubes)
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What are the two small remnants of the paramesonephric ducts in males?
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appendix testis, prostatic utricle
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What are the three structures that start off the external genitalia?
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Genital tubercle, genital swelling, cloacal fold (which splits into urogenital and anal folds)
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What is external genitalia development dependent upon?
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Testosterone
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What germ layer is the inside of the tip of the glans penis made of?
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Ectodermal cord
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What is the presentation if there is failure to canalize the ectodermal cord or fusion of the urethral folds?
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Hypospadias (1/300 male births)
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What is the name of the condition where the testes fail to descend?
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Cryptorchidism
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What developmental defect can cause a congenital hernia?
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patent vaginal process (where descent of testes occurs)
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When coelomic fluid is trapped in the scrotum, it is called what?
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Hydrocele
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In a female, what doe the urethral folds form?
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Labia minora
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What causes uterine defects?
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Failed fusion of paramesonephric ducts
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