Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
22 Cards in this Set
- Front
- Back
|
Gregor Mendel
|
monk, father of genetics, experimented with pea plants
most influential in history |
|
|
Sir William Henry Bragg
Sir Lawerence Bragg |
discovered that we can de3duce the atomic structure of crystals from their X-ray diffraction patterns.
this helped watson and Crick |
|
|
Frederick Griffith
|
studied difference b/w disease causing strain of the pneumonia causing bacteria and a strain that didnt cause pneumonia
he was able to induce a non-pathogenic strain of the bacterium streptocus pneumoniae to become pathogenic |
|
|
Luria Delbruck Experiment
(Fluctuation Test) |
1943
demonstrated that genetic mutations arise in absence of selection, rather than being a response to selection won nobel in 1969 |
|
|
Cold Springs Harbor: Phage Group
|
Delbruck and Luria studied T phages
the phages attacked E coli and were made of DNA and proteins tried to figure out if DNA or proteins made genes |
|
|
Erwin Chargaff
|
1950- analyzed the base composition of DNA in a # of organisms
He found that DNA composition varies from one species to another, making DNA a more credible candidate for the genetic material than protein |
|
|
Chargaffs Rules
|
Cytosine-Guanine and Adenine-Thymine
this aided Watson and Crick in the discovery of the structure |
|
|
Avery, Macleod, and McCarty
|
worked on mystery of inheritence, continuing Frederick Griffiths work
experiment: bacteria are able to transfer genetic material thru a liquid medium tp ptjer nacteroa, transforming them. therefore, if bacteria transform when an organic molecule is placed in a liquid with them, then that molecule holds genetic information |
|
|
Alfred Hershey
|
worked w/ bacterophages with Luria and Delbruck in 1940.
observed that when two different strains of bacteriophage have infected the same bacteria, the two viruses can exchange genetic material |
|
|
Rosy "Bitch" Franklin
|
Took photo 51 at Kings in 1952 that helped watson and crick confirm the helical structure of DNA
it was published in Nature, along with some of her other work in 1953 |
|
|
Kings College
|
largest college of the University of London, with huge scientific charters
|
|
|
Johann Frederick Miescher
|
1869-identified a weakly acidic substance of unkown funcion in the nuclei of human white blood cells (DNA)
|
|
|
Robert Feulgen
|
German chemist who odeveloped a method for staining DNA known as the Feulgen Stain
Discovered that DNA is in the chromosomes |
|
|
DNA
|
deoxyribonucleic acid, a nucleic acid. nucleic acids are made up of polynucleotide chains which are formed by many nucleotides bonded together
each nucleotide is made of 3 parts: the phosphate, the sugar, and the base |
|
|
Purines
|
Adenine and Guanine and Purines ( Andrew's Gay Pride)they are larger and have a double ring
|
|
|
pyramidines
|
Thymine and cytosine are pyrimadines ( Timmy cooks people) smaller and have a single ring
|
|
|
Nucleotides
|
have 3 components, a pentose sugar, an amino base, and a phosphate group
|
|
|
DNA polymerase
|
replicates DNA
|
|
|
helicases
|
unwinds (stretches) helix to allow DNA/RNA polymerase's entry
|
|
|
RNA polymerase
|
creates mRNA using sense strand
|
|
|
exons
|
tag start & stop places
|
|
|
introns
|
junk between exons
|
