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10 Cards in this Set
- Front
- Back
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What are the major events of hemostasis? (4)
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Vascular constriction, platelet plug formation, fibrin formation, fibrinolysis
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What is the average life span of platelets?
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7-10 days
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What are the predominant mediators of platelet production? (3)
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Thrombopoetin, IL-6, IL-11
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What is the primary defect in von Willebrand's disease?
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Failure of platelet aggregation
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Which congenital factor deficiency is associated with delayed bleeding after initial hemostatis?
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Factor XIII
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What is the most common intrinsic platelet defect?
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Storage pool disease
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Which clotting factors are consumed during coagulation?
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Factor I (Fibrinogen), Factor II (prothrombin), Factor V (proaccelerin), Factor VIII (antihemophilic factor), and platelets
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Fresh whole blood is a poor source of which two clotting factors?
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Platelets and factor VIII
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Which two clotting factors are unstable in banked whole blood
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Factors V and VIII (and platelets--24hrs)
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What is the most common clinical manifestation of a hemolytic transfusion reaction?
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Oliguria or Hemaglobinuria
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