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21 Cards in this Set

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  • Back

schizophrenia

delusions, hallucinations, disorganized speech, catatonic behavior, negative symptoms

brief psychotic disorder

sudden onset of psychotic symptoms, disorganized speech/behavior, duration is at least 1 episode a day for less than a month

schizophrenium disorder

schizophrenia-like psychoses that last at least 1 month and less than 6 months

schizoaffective disorder

major depressive episode or manic episode that occurs with symptoms of schizophrenia- 2 week period of delusions or hallucinations, mood symptoms present for over 50% of total duration of illness

delusional disorder

1 or more delusions for at least 1 month overall functioning not impaired, not odd behavior


-subtype: erotomania

delusions

erroneous belief that is fixed and firmly held despite clear evidence


-disturbance in content of thought


ex: made feelings, thought broadcasting, thought withdraw

hallucinations

sensory experiences that seem real, but occurs in absence of any external perceptual stimuli


-auditory is most common

disorganized speech

external manifestation of thought form, failure to make sense


-derailment, word salad


-neologisms: made up words

disorganized behavior

goal-directed activity disrupted, may not maintain minimal standard of hygiene

catatonia

striking behavior disturbances, may show a virtual absence of speech and movement, hold unusual posture

positive symptoms

excess or distortion in a normal repertoire of behavior and experience


-delusions and hallucinations

negative symptoms

absence of behaviors that are normally present


-emotions


-Alogia: lack of speech


Avolition: lack of desire, drive


Anhedonia: lack of pleasure

prevalence


male to female ratio


men onset


women onset

.5-1.5%


1.4:1


18-25


25-35 (estrogen protecting factor?)

risks and casual factors

-twins: increase for MZ than DZ twins


-molecular: unlikely its linked to 1 gene


-dopamine hypothesis: too much in neural synapses


serotonin: negative symptoms

cont.

-prenatal viral infection, rh incompatibility, early nutritional deficiency, birth complications, maternal stress


-urban living, immigration, cannabis abuse

diathesis-stress model

genetic factors--> brain


prenatal and perinatal events--> vulnerability-->



stress-->


developmental maturation process--> psychosis

clinical outcome of schizophrenia

38% function 15-25 years later



long-term institution is 12%



signs of illness with neg. symptoms is 33%

increased rates of mortality?

4x higher



suicide and cancer

treatment

antipsychotics- block dopamine receptors


-reduce positive symptoms


-psychoeducation


-CBT


-social skills training


-supported employment


-cognitive remediation

typical antipsychotic side effects

Tardive Dyskinesia


-marked involuntary movements of lips, tongue , hands and neck

Atypical

less likely to produce tardive dyskinesia


-60% stop using after 18 months