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59 Cards in this Set
- Front
- Back
define macule
patch? |
Macule: flat spot on skin measuring <1cm
Patch: >1cm |
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papule looks like?
nodule? |
• Papule: nonpustular, nonvesicular lesion on skin <1cm
• Nodule: >1cm |
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vesicle are?
Bulla? |
Vesicle: small blisters < 1cm
• Bulla:>1cm (some are tense some are flaccid) |
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Pustule: important?
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Pustule: A collection of leukocytes in the epidermis
- acne, staph |
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Plaque:disease seen in?
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Plaque: broad, elevated flat lesions > 1cm
psorias |
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What are secondary lesions?
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adjective to describe the primary lesion
• Scale, Crusts • Erosion • Fissure • Eschar |
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atopic dermatitis
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cheeks spairing oral area
papular erythematous rash allergic shiners |
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After knowing lesion is erythematous what next?
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whether non-scaling or scaling
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After knowing lesion is erythematous and that it is non-scaling what is next?
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1. localized with spepsis
2. localized without sepsis 3. generalized +- systemic signs |
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After knowing lesion is erythematous and that it is non-scaling what is next and 1. localized with spepsis what could it be?
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cellulitis
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After knowing lesion is erythematous and that it is non-scaling what is next and 1. localized without spepsis what could it be?
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insect bits, acne, hemanigioma
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After knowing lesion is erythematous and that it is non-scaling what is next and 1. generalized with/without systemic signs what could it be?
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urticaria
erythema nodosum viral exanthemas annular erythemas |
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After knowing lesion is erythematous and that it is scaling... what is next?
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Is it...
papulosquamous eczematous |
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After knowing lesion is erythematous and that it is scaling and papulosquamous
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pityriasis
psoriasis tinea corporis syphillis |
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After knowing lesion is erythematous and that it is scaling and eczematous
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atopic dermatitis
contact dermatitis scabies others |
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Acute, rapidly spreading nonsuppurative infection of the skin and underlying soft tissue NOT including the muscle
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cellulitis
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clinical findings of cellulits
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commonly on extremity
tender, warm poorly demarcated boggy plaque |
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differential of cellulitis
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– Venous thrombosis
– Gout – Lipodermatosclerosis – Chronic stasis dermatitis |
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25 yr old f painful erythematous nodules on anterior surface of both legs and extensor surface both arms with pain and swelling lower leg and ankles
poorly defined borders 2-6 diameter, hard nodular, painfull |
erythema nodosum
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erythema nodosum associated with?
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cocidioidomycosos, histoplasma
Sarcoidosis anterior portion of shin lesion of subcutaneous fat |
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classic description of psoriasis?
What is skin sign? |
silky- silver scales
neutrophil collections in stratum corneum (munro microabsesses) - auspitz sign- push on skin and scales pull off |
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5 p's of lichen planus
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psoriasis
postular puriritic painful Flat topped papules |
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Flat topped papules with a classic white reticular pattern on the suface
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lichen planus
- associated with HepC |
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classic "hearald patch plaque" followed by a rash that follows cleavage line
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pityriasis rosea with "christmas tree"
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microscopic findings for psoriasis?
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downward extension of basal layer
-extension of papillary drmis close to surface of epithelium |
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Varicella- zoster usually has what podrome?
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radicular pain and itchng before rash occurs
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morphologic term used to describe a specific class of dermatologic conditions containing mainly papules and scale ( squamous) in their diagnostic description
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papulosquamous
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what is genetic status and gene of psoriasis vulgaris
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HLA B-13 Auto dom, immune T cell reaction
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scaley white plaques often seen over elbows/knees made worse by what drug?
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psoriasis vulgaris made worse by lithium, B-blockers
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seborrheic dermatitis caused by?
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p. ovale often M. furfer
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Corynebacterium minutissimum – gram positive rod, part of the normal skin flora
causes what seen in the arm pits and tropics |
erythrasma
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Red/brown scaly macules with an erosive collarette-like scale
diagnosed with? |
erythrasma use wood's lamp
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Lichen planus associated with which disease?
What lesion shows up 50% of the time in LP? increase risk of? |
hep C
- oral mucosa produces a fine, white net-like lesion (wickham's striae) increase risk of SCC |
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rose colored plaque on trunk.... herald patch (rash on lines of cleavage)
When doe we usually see this? |
pityriasis rosea (shows christmas tree" rash)
spring and fall |
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MCC tinea corporis
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T. rubrum
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with nail and hand involvement with tinea what is treatment?
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must give topical and oral antifungal
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Reddish-orange scaling plaques of unknown etiology with palmoplantar keratoderma and follicular keratotic papules
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pityriasis rubra pilaris
AD |
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How many types of pityriiasis rubra?
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6 types
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Cutaneous T cell lymphoma
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scattered pink erythematous plaque (salmon colored) seen in T-cell lymphoma
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Scaling plaques which mimic eczema
• Itchy • Multiple different shades of red-brown • Round, oval annular or bizarre shape |
could be t-cell lymphoma
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Erythematous papule or plaque with modest
amount of scale • Hypopigmented or hyperpigmented • Scarred • Mucosal, palms and soles |
discoid lupus
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cornerstone of treatment for discoid lupus
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antimalarials!
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GA (granuloma annulare) occurs most often on? has strong associated with?
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dorsum of hands and feet associated with DM
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drugs that cause...
a. photoxic drug eruption b. accumulation of silver c. over dosage pupura |
a. tetracyclines
b. sliver nitrate c. pupura with coumadin |
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Define vesicle
Define Bulla Define Vesiculobullous |
Vesicle- a blister less than 1cm in size
• Bulla- a blister greater than 1cm in size • Vesiculobullous- blisters between <1cm to >1cm |
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Highly contagious gram positive bacterial infection of the superficial layers of the skin Staphylococcus aureus group 2 phage 71/GABHS
30% nares small percentage groin, hand, rectum, pharynx |
impentigo
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Where does scolded skin syndrome occur?
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blister at granular layer of the of the epidermis due to splitting of the desmosomes
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IgG auto Ab and type II hypersensativity basal cells sees tombstone
+nikolsky sign is what? |
pemphigus vulgaris
- outer epidermis separates from the basal layer with minimal pressure |
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Flaccid bulla on the skin with an erosion in the oral mucosa
• + Nikolsky’s sign • + Asboe-Hansen sign- lateral pressure on the bulla will spread the bulla to uninvolved skin |
pemphigus vulgarist
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HSV2 is dormant in where?
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sensory ganglia
shows multinucleated squamous cells with eosinophilic intranuclear inclusions |
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• “oval teardrop on an erythematous base”
• “dew drop on a rose pedal” |
varicella zoster (chicken pox)
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varicella zoster aka chicken pox spares what usually?
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distal extremity
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Chronic, autoimmune, subepidermal blistering disease that RARELY involves the oral mucosa
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bullous pemphigoid
- involvement of the subepidermis |
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• Subacute or acute formation of tense bulla
• UV radiation or drug induced • Bullous, vesicular, urticarial, acral in children • Causes include genetic, age, epitope spreading |
bullous pemphigoid
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idiopathic photodermatoses relating to sun exposure with papules, vescicles, and plaques
MC seen in what population? |
American Indians
UV-A induced ICAM-1 polymorphous light eruption |
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Immune mediates skin disease with a gluten sensitive enteropathy
How does this present clinically? |
dermatitis herpetiformis
IgA-anti- IgA deposits at the tips of the dermal papillae = super itching, symmetric blisters |
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targetoid or iris shaped macules or
vesiculopapules on the palms or soles |
erythema multiforme
- sufa other meds - myco pneumonia or HSV if recurrent |
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Extensive full thickness skin detachment could have 80% mortality if untreated
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toxic epidermal necrolysis
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toxic epidermal necrolysis treatment?
compared to scalded skin syndrome? |
put em in burn unit
- staph scolded skin separates upper layer of the epidermis, this shit separates dermis/epidermis |