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59 Cards in this Set

  • Front
  • Back
define macule
patch?
Macule: flat spot on skin measuring <1cm
Patch: >1cm
papule looks like?

nodule?
• Papule: nonpustular, nonvesicular lesion on skin <1cm
• Nodule: >1cm
vesicle are?

Bulla?
Vesicle: small blisters < 1cm
• Bulla:>1cm (some are tense some are flaccid)
Pustule: important?
Pustule: A collection of leukocytes in the epidermis

- acne, staph
Plaque:disease seen in?
Plaque: broad, elevated flat lesions > 1cm
psorias
What are secondary lesions?
adjective to describe the primary lesion
• Scale, Crusts • Erosion • Fissure • Eschar
atopic dermatitis
cheeks spairing oral area
papular erythematous rash
allergic shiners
After knowing lesion is erythematous what next?
whether non-scaling or scaling
After knowing lesion is erythematous and that it is non-scaling what is next?
1. localized with spepsis
2. localized without sepsis
3. generalized +- systemic signs
After knowing lesion is erythematous and that it is non-scaling what is next and 1. localized with spepsis what could it be?
cellulitis
After knowing lesion is erythematous and that it is non-scaling what is next and 1. localized without spepsis what could it be?
insect bits, acne, hemanigioma
After knowing lesion is erythematous and that it is non-scaling what is next and 1. generalized with/without systemic signs what could it be?
urticaria
erythema nodosum
viral exanthemas
annular erythemas
After knowing lesion is erythematous and that it is scaling... what is next?
Is it...
papulosquamous
eczematous
After knowing lesion is erythematous and that it is scaling and papulosquamous
pityriasis
psoriasis
tinea corporis
syphillis
After knowing lesion is erythematous and that it is scaling and eczematous
atopic dermatitis
contact dermatitis
scabies
others
Acute, rapidly spreading nonsuppurative infection of the skin and underlying soft tissue NOT including the muscle
cellulitis
clinical findings of cellulits
commonly on extremity
tender, warm poorly demarcated boggy plaque
differential of cellulitis
– Venous thrombosis
– Gout
– Lipodermatosclerosis
– Chronic stasis dermatitis
25 yr old f painful erythematous nodules on anterior surface of both legs and extensor surface both arms with pain and swelling lower leg and ankles
poorly defined borders 2-6 diameter, hard nodular, painfull
erythema nodosum
erythema nodosum associated with?
cocidioidomycosos, histoplasma
Sarcoidosis
anterior portion of shin
lesion of subcutaneous fat
classic description of psoriasis?

What is skin sign?
silky- silver scales
neutrophil collections in stratum corneum (munro microabsesses)

- auspitz sign- push on skin and scales pull off
5 p's of lichen planus
psoriasis
postular
puriritic
painful
Flat topped papules
Flat topped papules with a classic white reticular pattern on the suface
lichen planus
- associated with HepC
classic "hearald patch plaque" followed by a rash that follows cleavage line
pityriasis rosea with "christmas tree"
microscopic findings for psoriasis?
downward extension of basal layer
-extension of papillary drmis close to surface of epithelium
Varicella- zoster usually has what podrome?
radicular pain and itchng before rash occurs
morphologic term used to describe a specific class of dermatologic conditions containing mainly papules and scale ( squamous) in their diagnostic description
papulosquamous
what is genetic status and gene of psoriasis vulgaris
HLA B-13 Auto dom, immune T cell reaction
scaley white plaques often seen over elbows/knees made worse by what drug?
psoriasis vulgaris made worse by lithium, B-blockers
seborrheic dermatitis caused by?
p. ovale often M. furfer
Corynebacterium minutissimum – gram positive rod, part of the normal skin flora
causes what seen in the arm pits and tropics
erythrasma
Red/brown scaly macules with an erosive collarette-like scale
diagnosed with?
erythrasma use wood's lamp
Lichen planus associated with which disease?

What lesion shows up 50% of the time in LP? increase risk of?
hep C

- oral mucosa produces a fine, white net-like lesion (wickham's striae)
increase risk of SCC
rose colored plaque on trunk.... herald patch (rash on lines of cleavage)
When doe we usually see this?
pityriasis rosea (shows christmas tree" rash)


spring and fall
MCC tinea corporis
T. rubrum
with nail and hand involvement with tinea what is treatment?
must give topical and oral antifungal
Reddish-orange scaling plaques of unknown etiology with palmoplantar keratoderma and follicular keratotic papules
pityriasis rubra pilaris
AD
How many types of pityriiasis rubra?
6 types
Cutaneous T cell lymphoma
scattered pink erythematous plaque (salmon colored) seen in T-cell lymphoma
Scaling plaques which mimic eczema
• Itchy
• Multiple different shades of red-brown
• Round, oval annular or bizarre shape
could be t-cell lymphoma
Erythematous papule or plaque with modest
amount of scale
• Hypopigmented or hyperpigmented
• Scarred
• Mucosal, palms and soles
discoid lupus
cornerstone of treatment for discoid lupus
antimalarials!
GA (granuloma annulare) occurs most often on? has strong associated with?
dorsum of hands and feet associated with DM
drugs that cause...
a. photoxic drug eruption
b. accumulation of silver
c. over dosage pupura
a. tetracyclines
b. sliver nitrate
c. pupura with coumadin
Define vesicle

Define Bulla

Define Vesiculobullous
Vesicle- a blister less than 1cm in size
• Bulla- a blister greater than 1cm in size
• Vesiculobullous- blisters between <1cm to >1cm
Highly contagious gram positive bacterial infection of the superficial layers of the skin Staphylococcus aureus group 2 phage 71/GABHS

30% nares small percentage groin, hand, rectum, pharynx
impentigo
Where does scolded skin syndrome occur?
blister at granular layer of the of the epidermis due to splitting of the desmosomes
IgG auto Ab and type II hypersensativity basal cells sees tombstone
+nikolsky sign is what?
pemphigus vulgaris

- outer epidermis separates from the basal layer with minimal pressure
Flaccid bulla on the skin with an erosion in the oral mucosa
• + Nikolsky’s sign
• + Asboe-Hansen sign- lateral pressure on the bulla will spread the bulla to uninvolved skin
pemphigus vulgarist
HSV2 is dormant in where?
sensory ganglia
shows multinucleated squamous cells with eosinophilic intranuclear inclusions
• “oval teardrop on an erythematous base”
• “dew drop on a rose pedal”
varicella zoster (chicken pox)
varicella zoster aka chicken pox spares what usually?
distal extremity
Chronic, autoimmune, subepidermal blistering disease that RARELY involves the oral mucosa
bullous pemphigoid
- involvement of the subepidermis
• Subacute or acute formation of tense bulla
• UV radiation or drug induced
• Bullous, vesicular, urticarial, acral in children
• Causes include genetic, age, epitope spreading
bullous pemphigoid
idiopathic photodermatoses relating to sun exposure with papules, vescicles, and plaques
MC seen in what population?
American Indians
UV-A induced ICAM-1
polymorphous light eruption
Immune mediates skin disease with a gluten sensitive enteropathy
How does this present clinically?
dermatitis herpetiformis
IgA-anti- IgA deposits at the tips of the dermal papillae

= super itching, symmetric blisters
targetoid or iris shaped macules or
vesiculopapules on the palms or soles
erythema multiforme
- sufa other meds
- myco pneumonia or HSV if recurrent
Extensive full thickness skin detachment could have 80% mortality if untreated
toxic epidermal necrolysis
toxic epidermal necrolysis treatment?
compared to scalded skin syndrome?
put em in burn unit

- staph scolded skin separates upper layer of the epidermis, this shit separates dermis/epidermis