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14 Cards in this Set
- Front
- Back
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**drug of choice to treat nephrotoxicity from cisplatin
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**amifostine
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**drug of choice to treat cardiotoxicity from doxorubicin
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**dexrazoxane
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**drug of choice to treat systemic toxicity from methotrexate
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**Leucovorin
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**drug of choice to treat hemorrhagic cystitis from Ifosphamide
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**Mesna
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two EPO stimulating agents
used for treatment of anemia in patients **what blood tests should be monitored? |
Epoetin alpha
Darbepoetin alpha **retic and RBC count |
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black box warning for epoetin alpha and darbepoetin alpha
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increased risk of CV reactions in patients w/ Hgb > 12
increased DVT in pre-op patients increased risk of tumor/disease progression in cancer patients |
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common side effect of epoetin alpha and darbepoetin alpha
what supplement should they take? |
iron deficiency anemia
iron |
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**two drugs that stimulate the production of granulocytes
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**Filgrastim and Pegfilgrastim
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**drug that stimulates the production of granulocytes and macrophages
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**Sargramostim
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**drug used to treat thrombocytopenia in patients
major side effect of this drug? |
Oprelvekin (IL-11)
fluid retention |
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4 drugs used to treat highly emetogenic chemotherapy pts
what is their MoA? |
Dolasetron
Granisetron Ondansetron Palonosetron serotonin type 3 receptor antagonists in the brain and the gut |
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most important drug for treatment of moderately emetogenic chemotherapy pts
what is its MoA |
Aprepitant
NK1 receptor antagonist |
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premier standard of care for chemotherapy induced nausea and vomiting (CINV)
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5-HT3 receptor antagonist
NK1 receptor antagonist corticosteroid lorazepam (+/-) |
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Hyperuricemia treatments associated w/ chemotherapy agents?
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Allopurinol - xanthine oxidase inhibitor
Probenecid - Blocks uric acid tubular reabsorption |
