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8 Cards in this Set

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Oldest antifungal, only used topically:

How to treat oral thrush in infants, older kids, mothers:

Drug for topical or vaginal fungal infections, OTC:

DOC for systemic fungal infections:
Nystatin

infants - apply to infant
child - "Swish and swallow"
mother - Fluconazole PO, clean nipple

Miconazole (Monistat)

Ampho B
Major toxicity for ketoconazole?

Itraconazole is used for what infections?

Terbinafine (Lamisil):
indications, AFE, ADR's:

Drug that has low efficicacy by itself, but may be beneficial in combination:
hepatic

hair, nails

onychomycosis, PO/topical, ADR's - GI, taste, allergic, HEPATIC

Ciclopirox
Given PO/IV, DI's with warfarin, phenytoin, single oral dose for vaginal candidiasis:

Only antifungal indicated in pregnancy:

Antifungal for ophthalmic use:
Fluconazole (Diflucan)

fluconazole

Natamycin
12 y/o, fever, fatigue, fleeting joint pain, rash with active border/central clearing, lives in Connecticut:

Should you Gram stain or culture spirochetes?

Species of tick that transmits:

Tx?
Lyme disease - B. burgdoferi

No - don't grow or stain well

deer tick- Ixodes sp.

Doxycycline
12 y/o, ulcer on wrist, lymph node swelling, fever, HA, muscle aches, played with rabbits:

What tick species?

What systems affected?

Tx?

Most common type?
tularemia - F. tularensis

Dermacentor sp.

lymph, blood, maybe lungs/GI, +rash

Streptomycin, Gent, Tet

ulceroglandular
44 y/o, fever, malaise, HA, myalgia, painful inguinal swelling, insect bite, buboes:

Bacteria appearance on slide?

Reservoir for Y. pestis?

Systems involved? Complications?

Tx?
plague - Y. pestis

G- bacilli, safety pin appearance

rodents (rat fleas)

skin entry, lymph nodes, sepsis, hemorrhagic illness, spleen, liver, lungs, CNS - complications of DIC

Streptomycin, PCN
6 y/o, fever, HA, myalgia, dry cough, petechial rash on extremities, including palms/soles, lives in NC:

Characteristics of bacteria?

Which tick species in Eastern and Western US? SW US?
RMSF - R. rickettsii

Obligate intracellular bacteria - Gram-, requires Coenzyme A, NAD, ATP (can't make own ATP)

E - dog tick (Dermacentor)
W - wood wick (Dermacentor)
SW - Lone Star tick - Amblyomma
Pathogenesis of RMSF:

Treatment?

28 y/o from Florida with fever, chills, HA, myalgia, tick bite, characteristic inclusion bodies in leukocytes:

Infectious form of Ehrlichia?

Treatment for Ehrlichiosis?
Vascular endothelial cells, creates foci, spread to smooth muscle --> increased vascular permeability --> edema, low proteins, decreased perfusion

Tet or Chloramphenicol

Ehrlichia

Elementary body

Tet, Doxy, chloramphenicol