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8 Cards in this Set
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Oldest antifungal, only used topically:
How to treat oral thrush in infants, older kids, mothers: Drug for topical or vaginal fungal infections, OTC: DOC for systemic fungal infections: |
Nystatin
infants - apply to infant child - "Swish and swallow" mother - Fluconazole PO, clean nipple Miconazole (Monistat) Ampho B |
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Major toxicity for ketoconazole?
Itraconazole is used for what infections? Terbinafine (Lamisil): indications, AFE, ADR's: Drug that has low efficicacy by itself, but may be beneficial in combination: |
hepatic
hair, nails onychomycosis, PO/topical, ADR's - GI, taste, allergic, HEPATIC Ciclopirox |
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Given PO/IV, DI's with warfarin, phenytoin, single oral dose for vaginal candidiasis:
Only antifungal indicated in pregnancy: Antifungal for ophthalmic use: |
Fluconazole (Diflucan)
fluconazole Natamycin |
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12 y/o, fever, fatigue, fleeting joint pain, rash with active border/central clearing, lives in Connecticut:
Should you Gram stain or culture spirochetes? Species of tick that transmits: Tx? |
Lyme disease - B. burgdoferi
No - don't grow or stain well deer tick- Ixodes sp. Doxycycline |
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12 y/o, ulcer on wrist, lymph node swelling, fever, HA, muscle aches, played with rabbits:
What tick species? What systems affected? Tx? Most common type? |
tularemia - F. tularensis
Dermacentor sp. lymph, blood, maybe lungs/GI, +rash Streptomycin, Gent, Tet ulceroglandular |
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44 y/o, fever, malaise, HA, myalgia, painful inguinal swelling, insect bite, buboes:
Bacteria appearance on slide? Reservoir for Y. pestis? Systems involved? Complications? Tx? |
plague - Y. pestis
G- bacilli, safety pin appearance rodents (rat fleas) skin entry, lymph nodes, sepsis, hemorrhagic illness, spleen, liver, lungs, CNS - complications of DIC Streptomycin, PCN |
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6 y/o, fever, HA, myalgia, dry cough, petechial rash on extremities, including palms/soles, lives in NC:
Characteristics of bacteria? Which tick species in Eastern and Western US? SW US? |
RMSF - R. rickettsii
Obligate intracellular bacteria - Gram-, requires Coenzyme A, NAD, ATP (can't make own ATP) E - dog tick (Dermacentor) W - wood wick (Dermacentor) SW - Lone Star tick - Amblyomma |
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Pathogenesis of RMSF:
Treatment? 28 y/o from Florida with fever, chills, HA, myalgia, tick bite, characteristic inclusion bodies in leukocytes: Infectious form of Ehrlichia? Treatment for Ehrlichiosis? |
Vascular endothelial cells, creates foci, spread to smooth muscle --> increased vascular permeability --> edema, low proteins, decreased perfusion
Tet or Chloramphenicol Ehrlichia Elementary body Tet, Doxy, chloramphenicol |