Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
12 Cards in this Set
- Front
- Back
|
What cells stain with S-100?
Sweat duct got plugged, drop of fluid visible in the epidermis, or duct popped: Disease where the keratin doesn't shed, produces alligator-like pattern of scales: Dominant form is caused by what? |
melanocytes, Langerhans cells
heat rash, miliaria ichthyosis Defective synthesis of filaggrin |
|
|
Severe form of ichthyosis, includes people with defective K1 and K10 keratins, transglutaminases:
T-cells attack melanocytes, creates sharply circumscribed patches: When do you see urticaria pigmentosa? |
lamellar ichthyosis
vitiligo mastocytosis- hyperplasias of mast cells |
|
|
Hives are what type of immune injury?
Contact dermatitis is what type of immune injury? What does phytodermatitis result from? |
Type I - histamine causes vessel dilation, leakage into dermis
Type IV - APC is Langerhans cell "fruit mask", "Club Med" dermatitis - photosensitivity from psoralens in plants (limes, lemons, celery) |
|
|
T-cells attack epidermis and dermal vessels:
Serious form of EM, cebrile systemic illness with purpura and mucosal involvement: Dermatologic emergency, full-thickness necrosis of 30% or more epidermis: What is panniculitis? |
erythema multiforme
Stevens-Johnson syndrome Toxic Epidermal Necrolysis inflammation of fat under the dermis |
|
|
Tender red bumps on shins, fibrosis with mixed inflammatory infiltration:
Proliferation of epithelial cells, Auspitz's sign, Koebner's phenomenon: Immune system attacks basal layer, "5 P's": |
Erythema nodosum
psoriasis Lichen planus |
|
|
Butterfly rash, sharply circumscribed scaly, shiny, depigmented red patches, exacerbated by sunlight:
What do you see histologically? |
Discoid lupus
infiltrate of lymphocytes, hyperkeratosis (keratin plugs), hydropic change of basal layer |
|
|
Name for solid mass of sebum and keratin from a problem follicle in acne:
What are open and closed comedones? |
comedone
open - blackheads - oxidized lipid from exposure to air closed - buried plug, "whitehead" |
|
|
Autoimmune destruction of desmosomes of stratified squamous epithelium, +Nikolsky's sign, Auto-Ag is desmoglein 3:
Auto-Ag is the hemidesmosome, generally milder than pemphigus vulgaris: Pompholyx (dyshydrotic eczema) has been linked to what? |
Pemphigus vulgaris
bullous pemphigus nickel allergty |
|
|
Auto-Ab's against reticulin, seen in sprue patients, symmetric patches of vesicle clusters:
minor, self curing disease caused by pox-virus speading by touching: First sign of pityriasis rosea? What is impetigo? |
dermatitis herpetiformis
molluscum contagiosum herald patch Bacterial infection of the epidermis, usually Staph/Strep, honey-colored lesions, damages desmoglein |
|
|
"Flesh-eating" disease, caused by GAS, MRSA:
Classic presentation? One wrestler passes herpes to another: What produces SSS? |
necrotizing fasciitis
patient with intense pain disproportional to infection herpes gladiatorum Staph epidermolytic toxin A, B |
|
|
Neutrophils invade/damage upper dermis/epidermis, no underlying vasculitis, usually a paraneoplastic syndrome:
Flaky, oily dermatitis that tends to occur in the nasolabial folds, center of the chest, scalp: World's mildest disease, common faint skin eruption of upper torso: |
Sweet's syndrome
seborrheic dermatitis Tinea versicolor |
|
|
Favorite sites for scabies?
Localized, generalized loss of hair for no obvious reason: Masses of tri-G and cholesterol-laden macrophages: Why do people have curly hair (best guess)? |
Fingers, penis
alopecia areata Xanthomas more transglutaminase cross-linking on one side |
