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18 Cards in this Set
- Front
- Back
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Pt. is positve for HLA-B5701. What drug do you avoid?
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Abacavir
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Pt. is CCR5 negative. What drug do you NOT give?
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Maraviroc
MOA: CCR5 antagonist |
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What drug should you avoid during the 1st trimester of pregnancy?
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Efavirenz
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What 2 NRTI's are interchangeable and should not be given together?
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Emtrictiabine
Lamivudine |
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What drug has cross-resistance?
Which group does not? |
Does: NNRTI's
Does NOT: PI's |
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What do all PI drugs end in?
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-navir
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What NRTI is associated w/ lipodystrophy, peripheral neuropathy, and pancreatitis?
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stavudine (one to avoid in most circumstances)
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What two NRTI's given in combination are BAD NEWS for toxicity?
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Didanosine & Stavudine
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What two drugs increase bilirubin?
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Atazanavir
Indinavir |
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What is the main purpose of give ritanovir?
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"boosting" --> inhibits CYP3A4 and increases effectiveness of other PI's
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What is the MOA of Enfuvirtide?
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Fusion inhibitor (binds gp41)
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What are 4 drugs recommended to give during pregnancy?
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Zidovudine (NRTI)
Nevirapine (NNRTI) Lamivudine (NRTI) Lopinavir/r (PI) |
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What is the MOA of Raltegravir?
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inhibits integrase
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When should you start prophylaxis for pneumocystis pneumonia?
What is the DOC? Alternative? |
CD4 <200
DOC: TMP-SMX Alt: dapsone |
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When should you start prophylaxis for Toxoplasma gondii encephalitis?
What is the DOC? Alternative? |
CD4 <100
doc: TMP-SMX Alt: dapsone |
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When should you start prophylaxis for disseminated mycobacterium avium?
What is the DOC? Alternative? |
CD4 <50
DOC: Azithromycin or clarithromycin Alt: RFB |
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When should you start prophylaxis for coccidiodomycosis?
What is the DOC? Alternative? |
CD4 <250
DOC: fluconazole, itraconazole |
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When should you discontinue mucosal candidiasis prophylaxis?
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not applicaple.... just know that if you discontinue, do it after CD4.200
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