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29 Cards in this Set
- Front
- Back
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What is immunization?
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induction of an active immune response triggered by antigenic stimulation with a vaccine
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What is vaccination?
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attempt in immunization by giving a vaccine
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What is active immunization?
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induction of an active immune response in the host by administering a vaccine
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What is passive immunity?
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the administration of serum or immunoglobulins from one individual donor to recipient
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What is a humoral immunity?
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-induction of antibodies by B cells in response to exposure to antigen
- the first response is IgM |
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What is a cell mediated immunity?
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-cell mediated destruction
--requires antigen presentation to T cells |
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How long does it take for a response to develop after animals vaccinated resulting in immunization?
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first response take days to weeks to develop
second response takes minutes to hours |
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What is an infectious/living vaccine?
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attenuated/avirulent/modified live organism
usually core vaccines |
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What is a noninfectious or non living vaccine?
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inactivated/killed/dead
usually elective vaccines |
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T/F
Only noninfectious vaccines are recombinant? |
False
both live and dead vaccines are recombinant recombinant means high modification not a whole infectious agent present |
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What are the pros of a live vaccines?
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produces good CMI and long humeral immunity
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What are the cons of live vaccines?
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immunosuppression
vaccine induce mild disease Shedding in environment |
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What are the pros of a killed vaccine?
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safer than modified live vaccine
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What are the cons of a killed vaccine?
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have to give a larger antigenic dose to induce immunity,often have an adjuvant and produce weaker protection than modified life vaccine
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Where should you give your vaccine?
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low on the leg
rabies in the right others in left hind |
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What are reasons for vaccines not being 100% effective?
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improper storage
improper administration incubation of disease immunocompromised non responders improper dose vaccine interference persistent maternal antibodies Sick animal |
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What is important information do you record after administering a vaccination?
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date given
route given site manufacturer serial number batch of vaccine expiration date |
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What should you not used a modified live vaccine?
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in pregnant animals
in young animals (modified live intranasal is safe) |
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What are signs of local adverse reactions?
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mild swelling, irritation
firm granulomatous reactions fibrosarcoma |
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What signs do you see with systemic illness due to vaccine reactions?
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malaise
irritability fever last one to two days |
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What are Type I immunologic reactions?
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see facial edema
IgE response treat with glucocorticoids treat with epi if anaphylaxis |
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What are Type II reactions?
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antibody production against self
use immunosuppressive dose of glucocorticoids |
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What are Type III reactions
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immune complex desposition
canine adenovirus 1 - corneal edema serum sickness |
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What are the core vaccines in dogs?
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Distemper
Rabies Hepatitis Parvo |
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What are the elective vaccines in dogs?
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lepto
bordetella lyme parainfluenza |
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What are the core vaccines in cats?
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Rhinotracheitis
Calici Panleukopenia Rabies |
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What are the elective vaccines in cats?
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FIV
FeLV Chlamydia Bordetella |
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What is the core vaccine protocol in an animal that is colostrum deprived and under 3 weeks?
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active vax not recommended
passive immunity beneficial start vax at 3 weeks for every 3 weeks til 12 -16 weeks |
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What is the vaccine protocol in an animal that received colostrum?
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Start at 6-8 weeks
Give every 3-4 weeks Series ends at 16 weeks want to have vax present when maternal antibodies are down |
