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18 Cards in this Set

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At what age and sex does diabetes Mellitus occur in dogs and cats?
dogs: 7-9 years 2X more likely in females than in males

cats: 8 years, neutered males are most commonly seen
What are the common presenting clinical signs of a patient with diabetes mellitus?
PU/PD
Polyphagia
Weight loss
What causes polyuria in diabetes patients?
the osmotic pull of glucose
What causes polyphagia in diabetes patients?
satiety center cells can't take up glucose without insulin
What are differential diagnoses for polyphagia and weight loss?
diabetes mellitus
Hyperthyroid
GI malabsorption/maldigestion
What signs can lead to a definitive diangosis of Diabetes Mellitus?
-PU/PD
-Polyphagia
-Weight loss
-fasting hyperglycemia >200mg/dl
-Glucosuria
What can you use to make emergency diagnosis of diabetes mellitus?
PCV, TP, BG, Azostix (BUN), urine dipstick
BG >200-250, glucose ++ on dipstick
Is it possible for a cat to have hyperglycemia and glucosuria and not have diabetes mellitus? What is next test?
Yes, due to stress
Measure fructosamine to see if hyperglycemia is ongoing
Is diabetes curable in dogs?
What is treatment?
Cats?
Are cataracts common in dogs? What is result?
No
Insulin inj 2x a day forever
May be transient or lifelong
Yes
Blindness
What type of insulin do you use on dogs?
Cats?
What is the dose?
Frequency?
Route?
Intermediate- Lente or NPH
Long acting- Glargine/Detemir or PZI
0.25-0.5 units/kg
BID
SQ
What is the short acting insulin? When is it used?
How is it delivered?
Novalin R
In hospital for procedures
IV
What dose do you start with?
How often do you need to monitor Blood glucose?
For how many days?
Low and work up to the correct level for that pt
3-5 times per day
First 3 days
What diet changes should you make in a dog with diabetes mellitus?
diets high in complex carbs
carb restricted diet, high protein
What should you let the treated diabetic patient do before initiating or changing insulin dose before assessing efficacy?
let the patient equilibrate for 7 days
you want to test their blood glucose curve
T/F

It is better to give insulin to a sick Diabetic Patient.
False
do not give insulin
What cells do not need insulin to take up glucose?
-CNS
-liver
-RBCs
-lens of the eye
-proximal renal tubule cells
-beta cells of the pancreas
What is the most common form of DM in the cat?
What causes it?
What can trigger this?
Non-insulin dependent
Impaired secretion of insulin and insulin resistance
Obesity, genetics, insular amyloid deposition
What is type III DM?
Medication or other disease interfere with insulin