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19 Cards in this Set

  • Front
  • Back
What is the agent that causes salmon poisoning disease? What transmits it?
Neorickettsia helminthoeca
-Helminth transmitted rickettsial disease of Canidae
Neorickettsia helminthoeca are closely related to ___ and ____, but are more closely related to ______.
-closely related to Ehrlichia and anaplasma
-more closely related to Neorickettsia risticii which causes potomac horse fever
What disease is very similar to salmon poisoning but is not as severe? How are they different?
Elokomin fluke fever
-potentially another strain of N. helminthoeca
-Wider host range and low mortality
Do cats get rickettsial disease?
NOPE
What is the distribution of salmon poisoning disease?
Western slopes of the cascades
-we have it here
*What is the vector for Neorickettsia helminthoeca?
Trematode Nanophyetus salmincola
-harbors all stages of N. helminthoeca
What 3 hosts are required for completly of the trematode life cycle (Nanophyetus salmincola)?
1) Snail (coastal areas)
2) fish
-salmonids, some non-salmonids and giant salamander
3) Mammal or bird
-dogs develop disease
How are dogs infected with Neorickettsia helminthoeca?
Eating metacercariae infested fish
How long does it take for adult trematodes to develop in a dog that ate a metacercariae infested fish?
6 days
What happens after the adult trematodes develop in a dog?
Adults attach to intestine and inoculate the rickettsia
-may cause mild enteritis
Where do Neorickettsia go once they enter the blood stream?
Lymph nodes, spleen, thymus, liver, lungs, brain
-cause of death not known
*** How long is the incubation period of salmon poisoning disease?
5-*7 days
What is one of the primary signs of salmon poisoning disease?
Higher fever (104-107.6) that normalizes in 4-8 days
-patients often hypothermic before they die
-progressive vomiting and diarrhea
How does the course of Elokomin fluke fever vary from salmon poisoning disease?
-Incubation: 5-12 days
-Fever in plateau lasting 4 to 7 days
What are the lab changes associated with salmon poisoning disease?
non-specific
-thrombocytopenia (88%)
-Eosinophilia (77%)
What are 2 methods used to diagnose salmon poisoning disease?
1) Trematode eggs can be identified in feces
2) FNA of affected lymph nodes
-intracytoplasmic rickettsia in mononuclear cells
When can you find the trematode eggs in a fecal when trying to diagnose salmon poisoning disease?
5-8 days after ingestion of infected fish
-direct smear or washing sedimentation techniques
What is the therapy for salmon poisoning disease?
-Supportive therapy
-Antibiotics for rickettsia (tetracycline)
-praziquantel for the N. salmincola
-in-hospital
What are 2 ways to prevent salmon poisoning disease?
1) Avoid raw fish
-Metacercariae can remain viable for months in rotting fish carcasses
2) freezing fish at -20 C for 24 hours kills the metacercariae and the rickettsia