Salivary Glands Histo - Nbde I

Front 1

Largest salivary gland?

Back 1

Parotid gland

Front 2

Where does the duct of the parotid gland open?

Back 2

Opposite Max 2nd molar

Front 3

Where does duct of submandibular gland open?

Back 3

Sublingual caruncle

Front 4

Smallest of major salivary glands?

Back 4

Sublingual glands

Front 5

Sublingual glands open into floor of mouth via?

Back 5

Many small ducts & at sublingual caruncle

Front 6

Minor salivary glands are present throughout oral mucosa EXCEPT?

Back 6

Anterior palate & gingiva

Front 7

Minor salivary glands are what type of glands?

Back 7

Mostly mucus
-Except tongue: von Ebner's glands

Front 8

Salivary glands arise from?

Back 8

Oral epithelium (ectoderm)

Front 9

Secretory end pieces of salivary glands are known as?

Back 9

Acini

Front 10

What is the function of acini?

Back 10

Secrete primary saliva into common lumen

Front 11

Serous cells produce?

Back 11

Fluid rich in proteins & glycoproteins

Front 12

Serous acini & cell shape?

Back 12

Serous acini = spherical
cells = pyramidal

Front 13

Secretory granules of serous cells are located?

Back 13

Apically

Front 14

What membrane modifications are present on serous cells? (5)

Back 14

1. Short microvilli
2. Lateral interdigitations
3. Basal infolding - increease SA
4. Junctional complexes, hemidesmosomes, gap junctions
5. Intercellular caniculi- finger like projectsions of lumen

Front 15

Mucous cells produce?

Back 15

Mucins = glycoproteins

Front 16

Secretory end pieces of mucous cells are what shape?

Back 16

Tubular

Front 17

Mucous acini are sometimes associated with?

Back 17

Serous demilunes

Front 18

Large quantities of mucins are located where in the mucous cell?

Back 18

Apically

Front 19

Which cells lack intercellular caniliculi?

Back 19

Mucous cells

Front 20

Myoepithelial cells are contractile cells similar to smooth muscle but are derived from?

Back 20

Myoepithelial cells --> epithelium (ectoderm)

Smooth muscle cells --> mesenchyme (mesoderm)

Front 21

Myoepithelial cells are found where?

Back 21

Surround acini & intercalated ducts
Between basal lamina & secretory cells or ducts

Front 22

Myoepithelial cells are attached by?

Back 22

hemidesmosomes

Front 23

What are the roles of myoepithelial cells?

Back 23

1. Support secretory cells
2. Maintain duct patency
3. Signal to acinar cells
4. Tumor suppressor activity?

Front 24

Intercalated ducts begin?

Back 24

Within acinus

Front 25

What receives primary salivary from secretory cells?

Back 25

Intercalated ducts

Front 26

Intercalated ducts are lined by?

Back 26

Simple cuboidal epithelial cells

Front 27

What do intercalated ducts add to saliva? (2)

Back 27

1. Lysozyme
2. Lactoferrin

Front 28

What receives primary saliva from intercalated ducts?

Back 28

Striated ducts

Front 29

What forms a major portion of the duct system?

Back 29

Striated ducts

Front 30

Striated ducts have what type of cells?

Back 30

Columnar cells

Front 31

Basal striations of striated ducts are due to?

Back 31

Mitochondria & membrane infoldings

Front 32

What ducts are located in CT septa between lobules?

Back 32

Excretory ducts

Front 33

Tuft cells w/ long stiff microvilli & apical vesicles are found?

Back 33

Excetory ducts

Front 34

Glands are surrounded by?

Back 34

Capusle

Front 35

Divide glands into lobes & lobules
Transmit blood vessels, nerves & excretory ducts

Back 35

Septa

Front 36

What type of cells are found in CT of glands? (7)

Back 36

1. Fibroblasts
2. Macrophages
3. Dendritic cells
4. Mast cells
5. Plasma cells (IgA)
6. Adipose cells
7. granulocytes/lymphocytes

Front 37

Preganglionic parasympathetics come from what nuclei?

Back 37

Superior & inferior salvitory nuclei

Front 38

Preganglionic parasympathetics run w/ which nerves?

Back 38

Submandibular & sublingual -- VII
Parotid IX

Front 39

Postganglionic parasympathetics synapse in?

Back 39

Submandibular or otic ganglion

Front 40

Which nerves do postganglionic parasympathetics run w/?

Back 40

Lingual or auriculotemporal

Front 41

What is action of substance P & VIP?

Back 41

Induce secretion-- modulate effects of Ach & norepi, might affect bloodflow

Front 42

What is the action of neuropeptide Y & CGRP?

Back 42

Regulate blood flow

Front 43

Which salivary gland is pure serous?

Back 43

Parotid gland

Front 44

Which salivary gland has fat cells between acini, numerous long intercalated ducts & numerous striated ducts?

Back 44

Parotid gland

Front 45

Which salivary gland is mixed but mostly serous?

Back 45

Submandibular

Front 46

Which salivary gland is mixed but mostly mucous?

Back 46

Sublingual

Front 47

Minor salivary glands are mostly what type of gland?

Back 47

Mucous

Front 48

What type of glands are located on tongue associated w/ circumvallate papilla?

Back 48

von Ebner's glands

Front 49

Primary saliva is ____tonic?

Back 49

Isotonic

Front 50

What happens w/ the macromolecular components of primary saliva? (4)

Back 50

1. Modified, condensed & packaged by Golgi
2. Stored in secretory granules in apical part
3. When stimulated fuse w/ apical membrane & released by exocytosis

Front 51

Saliva is modified by?

Back 51

Duct cells

Front 52

What happens to Na & Cl during modification of saliva?

Back 52

Na & Cl are reabsorbed

Front 53

What is secreted into saliva during modification?

Back 53

K & HCO3

Front 54

Diseases that infect & replicated within salivary glands? (5)

Back 54

1. CMV
2. EBV
3. Herpes 6 & 7
4. Mumps
5. Bacterial infections