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5 Cards in this Set

  • Front
  • Back
What are the steps in viral replication?
Attachment, Entry, uncoating, replication, assembly, release
What is required for infection?
Adhesion is required for infection and is mediated by cell receptor virion binding molecules.
Can a cell be susceptable but not permissive?
Yes, a cell can have receptors to bind a virion but not have the intracellular machinery to allow the virus to replicate. So that cell would be susceptable but not permissive.
Regarding replication, dsDNA and ssDNA viruses both use DNA-dep DNA pol, but how do their replication cycles differ?
Since only dsDNA can be read by DNA polymerase, ssDNA must first be converted to double stranded DNA before the DNA polymerase can work.
Explain the replication strategy of gapped dsDNA.
Gapped DNA repaired

dsDNA transcribed to mRNA by DNA dep RNA pol

mRNA uses REVERSE TRANSCRIPTASE to make DNA with gaps

some mRNA is packaged