S1 - Falcon - Microbiology High Yield

Front 1

MCC of Post-Viral Lobar Pneumonia

(esp. in the nosocomial setting)

Back 1

- Staphylococcus Aureus

Front 2

MCC of Septic arthritis

MCC of Septic arthritis in kids and people over 50

Back 2

N. Gonorrheae
(monoarticular)

S. Aureus

Front 3

S. Aureus

- what are the effects of a Superantigen

Back 3

Increases PROLIFERATION of
- CD4 T cells
- APC cells

Increases SECRETION of
- CD4 T cell cytokines

(e.g.- TNF-a, IFN-gamma, IL-1, IL-2)

Front 4

S. Aureus

- list the Superantigen Exotoxins

Back 4

- Enterotoxins (heat labile)

- TSS Toxin

(NOTE: Exfoliatin released by S. aureus, but is NOT superantigen)

Front 5

ENDOCARDITIS BUGS:

- Prosthetic heart valves

- MCC of Subacute Bacterial Endocarditis (SBE)

- Undamaged heart valve

- IV Drug users

- Tricuspid

Back 5

- Staph. epidermitis

- Strep. viridans

- Staph. aureus

- Staph. aureus

- Staph. aureus

Front 6

Cornyebacterium Diphtheria Toxin

- what is the MOA of the toxin

- Rx of choice?

- Prevention how?

Back 6

- inhibits protein synthesis by ADP ribosylation of EF-2

- Erythromycin & Antitoxin

- Diphtheria Toxoid immunization

Front 7

Psuedomonas Aeruginosa

- name of toxin that inhibits Protein synthesis

- MOA of the toxin

Back 7

- Exotoxin A

- inhibits protein synthesis by ADP ribosylation of EF-2

Front 8

Neisseria Gonorrheae

- gram?

- what is the primary toxin?

Back 8

- Gram Negative Diplococci

- LOS
(not LPS as in N. meningitidis)

Front 9

Neisseria Gonorrheae

- oxidase?

- thus contains?

Back 9

- Oxidase positive

- contains cytochrome c

Front 10

Neisseria Gonorrheae

- media for culture

- list virulence factors

Back 10

- Chocolate agar
(Modified Thayer Marten)

- Capsule
- LOS
- IgA protease
- Pili

Front 11

Neisseria Gonorrheae

- ferments what sugar?

- what about for N. Meningitis?

Back 11

- Glucose only

- N. meningitidis ferments Glucose & Maltose

Front 12

Neisseria Gonorrheae

- genetic resistance to Rx?

Back 12

- Plasma mediated PCNase strains

Front 13

Neisseria Gonorrheae

- initial symptoms

- Rx?
(what if allergic to primary tx?)

Back 13

- discharge in first week after sex

- Ceftriaxone
(spectinomycin if allergic to PCN)

Front 14

Francisella Tularensis

- gram & morphology?

- infects what cells?

Back 14

- Gram Negative Rod

- Survives in Macrophages for prolonged period of time

Front 15

Francisella Tularensis

- Primary virulence factor

- Primary vector

- Primary reservoir

Back 15

- Capsule (antiphagocytic)

- Ticks

- wild rabbits

Front 16

Francisella Tularensis

- MC transmission

Back 16

- cleaning animal hides

Front 17

Francisella Tularensis

- requires what for growth?

Back 17

- cysteine

Front 18

Francisella Tularensis

- Rx

Back 18

- Streptomycin